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“It is concluded that nasogastric suction should not be used routinely following abdominal surgery." This is the concluding statement from a paper presented at the Pacific Coast Surgical Association and published in the American Journal of Surgery more than 50 years ago (Am. J. Surg 1957;94:257-61).

Since then innumerable randomized controlled trials and meta-analyses have confirmed that nasogastric tubes inserted prophylactically after abdominal surgery, even when gastrointestinal anastomoses have been constructed, are unnecessary. So how did this incontrovertible evidence impact my practice and that of most of my surgical colleagues? Not at all, at least not for many years. We continued our routine of torturing postoperative patients with nasogastric tubes because it had been drummed into us during residency and because we were uncomfortable not doing so. But why did we persist after convincing evidence to the contrary emerged?

Unfortunately it is not uncommon that even when good evidence exists, we fail to incorporate it into decision-making.  The comfort we enjoy with our standard way of doing things is often preferred to the discomfort – cognitive dissonance – we experience when confronted with mounting empirical evidence that challenges our beliefs. All too often, the cognitive dissonance is reduced by holding on to those notions with which we are most comfortable and ignoring or rejecting new information no matter how valid.

What is the harm? In the case of prophylactic nasogastric tubes, considerable discomfort has unnecessarily complicated the postoperative courses of millions of patients. Many trials have shown that aspiration and pneumonia, the adverse events for which the tubes were placed to prevent, occurred more frequently in patients with than those without nasogastric tubes.

Prophylactic gastric decompression is but one of many practices that have been continued long after their efficacy was disproven. How many radical mastectomies were performed after modified radical mastectomy, and then later partial mastectomy with radiation were shown with irrefutable data to provide equal survival with less disfigurement and fewer complications such as arm lymphedema? For many years after the indications for tonsillectomy were narrowed, this procedure continued to be more commonly done than was appropriate based on the evidence available.

Some hold on to their cherished habits more persistently and longer than others. In order to maintain consonance and avoid the stress of dissonance, I have known surgeons who have retained nearly all of the practices they learned from their mentors during residency long past their utility. Such individuals may insist that they alone prep their patients and that long outmoded suture and instruments be maintained on the operating room supply list. When new, and often proven to be superior, instruments, sutures, and pathways of care for their patients are introduced in their institutions, they find it difficult or even impossible to change.

In an era when the few controlled trials and meta-analyses available were buried within a surgical literature that was difficult to access and the term evidence-based surgery was not yet a part of our lexicon, such a rigid posture was often tolerated. I would hope that in most institutions and departments of surgery this is no longer the case. We live in a time when the imperatives of renewal and reevaluation of our practices are increasing. Therefore, reviewing new evidence, even that which goes against our established notions, and incorporating new proven methods, are essential to maintaining the highest standard of patient care.

Although many gray areas remain and there is often more than one best way to manage a surgical patient, our treatments should be based on the best evidence available rather than on what we learned 5, 10, or even 30 years ago. Fortunately, such evidence is now readily accessible. A notable example is “Evidence-based decisions in surgery,” surgical practice guidelines recently introduced by the American College of Surgeons (ACS) under the guidance of Dr. Lewis Flint.

“Evidence-based decisions in surgery” presently consists of 15 modules of the most common diseases and conditions encountered by general surgeons. These modules can be easily accessed by ACS Fellows on any mobile device at the point-of-care (http://ebds.facs.org). Surgical recommendations along with the strength of evidence (weak, moderate, or strong) for each are presented in an easy-to-interpret format. The modules have been developed by American College of Surgeons staff and been peer-reviewed by the Best Practices Workgroup of the College’s Board of Governors and by representatives of the Advisory Council for General Surgery. A consensus of the reviewers was used to determine the content of each module. It is emphasized that the purpose of these modules is to guide rather than dictate decision-making.

 

 

In addition to the strength of evidence for each recommendation, a clinical decision algorithm for a typical patient, suggested talking points for patient education, and key references on which the recommendations are based are also provided. Although clinical practice guidelines have been developed by a number of specialty surgical societies, I have found none that are as easy to digest and use in a busy clinical practice as “Evidence-based decisions in surgery.

So we no longer have an excuse to hold on to our cherished and venerable practices that are outmoded and possibly not in the best interest of our patients. The information needed to do it right is virtually one click of a mouse away. Try applying “Evidence-based decisions in surgery” in your practice. I am convinced you will find them valuable as you make decisions for the most appropriate care of your patients.

 

Dr. Rikkers is Editor in Chief of ACS Surgery News

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“It is concluded that nasogastric suction should not be used routinely following abdominal surgery." This is the concluding statement from a paper presented at the Pacific Coast Surgical Association and published in the American Journal of Surgery more than 50 years ago (Am. J. Surg 1957;94:257-61).

Since then innumerable randomized controlled trials and meta-analyses have confirmed that nasogastric tubes inserted prophylactically after abdominal surgery, even when gastrointestinal anastomoses have been constructed, are unnecessary. So how did this incontrovertible evidence impact my practice and that of most of my surgical colleagues? Not at all, at least not for many years. We continued our routine of torturing postoperative patients with nasogastric tubes because it had been drummed into us during residency and because we were uncomfortable not doing so. But why did we persist after convincing evidence to the contrary emerged?

Unfortunately it is not uncommon that even when good evidence exists, we fail to incorporate it into decision-making.  The comfort we enjoy with our standard way of doing things is often preferred to the discomfort – cognitive dissonance – we experience when confronted with mounting empirical evidence that challenges our beliefs. All too often, the cognitive dissonance is reduced by holding on to those notions with which we are most comfortable and ignoring or rejecting new information no matter how valid.

What is the harm? In the case of prophylactic nasogastric tubes, considerable discomfort has unnecessarily complicated the postoperative courses of millions of patients. Many trials have shown that aspiration and pneumonia, the adverse events for which the tubes were placed to prevent, occurred more frequently in patients with than those without nasogastric tubes.

Prophylactic gastric decompression is but one of many practices that have been continued long after their efficacy was disproven. How many radical mastectomies were performed after modified radical mastectomy, and then later partial mastectomy with radiation were shown with irrefutable data to provide equal survival with less disfigurement and fewer complications such as arm lymphedema? For many years after the indications for tonsillectomy were narrowed, this procedure continued to be more commonly done than was appropriate based on the evidence available.

Some hold on to their cherished habits more persistently and longer than others. In order to maintain consonance and avoid the stress of dissonance, I have known surgeons who have retained nearly all of the practices they learned from their mentors during residency long past their utility. Such individuals may insist that they alone prep their patients and that long outmoded suture and instruments be maintained on the operating room supply list. When new, and often proven to be superior, instruments, sutures, and pathways of care for their patients are introduced in their institutions, they find it difficult or even impossible to change.

In an era when the few controlled trials and meta-analyses available were buried within a surgical literature that was difficult to access and the term evidence-based surgery was not yet a part of our lexicon, such a rigid posture was often tolerated. I would hope that in most institutions and departments of surgery this is no longer the case. We live in a time when the imperatives of renewal and reevaluation of our practices are increasing. Therefore, reviewing new evidence, even that which goes against our established notions, and incorporating new proven methods, are essential to maintaining the highest standard of patient care.

Although many gray areas remain and there is often more than one best way to manage a surgical patient, our treatments should be based on the best evidence available rather than on what we learned 5, 10, or even 30 years ago. Fortunately, such evidence is now readily accessible. A notable example is “Evidence-based decisions in surgery,” surgical practice guidelines recently introduced by the American College of Surgeons (ACS) under the guidance of Dr. Lewis Flint.

“Evidence-based decisions in surgery” presently consists of 15 modules of the most common diseases and conditions encountered by general surgeons. These modules can be easily accessed by ACS Fellows on any mobile device at the point-of-care (http://ebds.facs.org). Surgical recommendations along with the strength of evidence (weak, moderate, or strong) for each are presented in an easy-to-interpret format. The modules have been developed by American College of Surgeons staff and been peer-reviewed by the Best Practices Workgroup of the College’s Board of Governors and by representatives of the Advisory Council for General Surgery. A consensus of the reviewers was used to determine the content of each module. It is emphasized that the purpose of these modules is to guide rather than dictate decision-making.

 

 

In addition to the strength of evidence for each recommendation, a clinical decision algorithm for a typical patient, suggested talking points for patient education, and key references on which the recommendations are based are also provided. Although clinical practice guidelines have been developed by a number of specialty surgical societies, I have found none that are as easy to digest and use in a busy clinical practice as “Evidence-based decisions in surgery.

So we no longer have an excuse to hold on to our cherished and venerable practices that are outmoded and possibly not in the best interest of our patients. The information needed to do it right is virtually one click of a mouse away. Try applying “Evidence-based decisions in surgery” in your practice. I am convinced you will find them valuable as you make decisions for the most appropriate care of your patients.

 

Dr. Rikkers is Editor in Chief of ACS Surgery News

“It is concluded that nasogastric suction should not be used routinely following abdominal surgery." This is the concluding statement from a paper presented at the Pacific Coast Surgical Association and published in the American Journal of Surgery more than 50 years ago (Am. J. Surg 1957;94:257-61).

Since then innumerable randomized controlled trials and meta-analyses have confirmed that nasogastric tubes inserted prophylactically after abdominal surgery, even when gastrointestinal anastomoses have been constructed, are unnecessary. So how did this incontrovertible evidence impact my practice and that of most of my surgical colleagues? Not at all, at least not for many years. We continued our routine of torturing postoperative patients with nasogastric tubes because it had been drummed into us during residency and because we were uncomfortable not doing so. But why did we persist after convincing evidence to the contrary emerged?

Unfortunately it is not uncommon that even when good evidence exists, we fail to incorporate it into decision-making.  The comfort we enjoy with our standard way of doing things is often preferred to the discomfort – cognitive dissonance – we experience when confronted with mounting empirical evidence that challenges our beliefs. All too often, the cognitive dissonance is reduced by holding on to those notions with which we are most comfortable and ignoring or rejecting new information no matter how valid.

What is the harm? In the case of prophylactic nasogastric tubes, considerable discomfort has unnecessarily complicated the postoperative courses of millions of patients. Many trials have shown that aspiration and pneumonia, the adverse events for which the tubes were placed to prevent, occurred more frequently in patients with than those without nasogastric tubes.

Prophylactic gastric decompression is but one of many practices that have been continued long after their efficacy was disproven. How many radical mastectomies were performed after modified radical mastectomy, and then later partial mastectomy with radiation were shown with irrefutable data to provide equal survival with less disfigurement and fewer complications such as arm lymphedema? For many years after the indications for tonsillectomy were narrowed, this procedure continued to be more commonly done than was appropriate based on the evidence available.

Some hold on to their cherished habits more persistently and longer than others. In order to maintain consonance and avoid the stress of dissonance, I have known surgeons who have retained nearly all of the practices they learned from their mentors during residency long past their utility. Such individuals may insist that they alone prep their patients and that long outmoded suture and instruments be maintained on the operating room supply list. When new, and often proven to be superior, instruments, sutures, and pathways of care for their patients are introduced in their institutions, they find it difficult or even impossible to change.

In an era when the few controlled trials and meta-analyses available were buried within a surgical literature that was difficult to access and the term evidence-based surgery was not yet a part of our lexicon, such a rigid posture was often tolerated. I would hope that in most institutions and departments of surgery this is no longer the case. We live in a time when the imperatives of renewal and reevaluation of our practices are increasing. Therefore, reviewing new evidence, even that which goes against our established notions, and incorporating new proven methods, are essential to maintaining the highest standard of patient care.

Although many gray areas remain and there is often more than one best way to manage a surgical patient, our treatments should be based on the best evidence available rather than on what we learned 5, 10, or even 30 years ago. Fortunately, such evidence is now readily accessible. A notable example is “Evidence-based decisions in surgery,” surgical practice guidelines recently introduced by the American College of Surgeons (ACS) under the guidance of Dr. Lewis Flint.

“Evidence-based decisions in surgery” presently consists of 15 modules of the most common diseases and conditions encountered by general surgeons. These modules can be easily accessed by ACS Fellows on any mobile device at the point-of-care (http://ebds.facs.org). Surgical recommendations along with the strength of evidence (weak, moderate, or strong) for each are presented in an easy-to-interpret format. The modules have been developed by American College of Surgeons staff and been peer-reviewed by the Best Practices Workgroup of the College’s Board of Governors and by representatives of the Advisory Council for General Surgery. A consensus of the reviewers was used to determine the content of each module. It is emphasized that the purpose of these modules is to guide rather than dictate decision-making.

 

 

In addition to the strength of evidence for each recommendation, a clinical decision algorithm for a typical patient, suggested talking points for patient education, and key references on which the recommendations are based are also provided. Although clinical practice guidelines have been developed by a number of specialty surgical societies, I have found none that are as easy to digest and use in a busy clinical practice as “Evidence-based decisions in surgery.

So we no longer have an excuse to hold on to our cherished and venerable practices that are outmoded and possibly not in the best interest of our patients. The information needed to do it right is virtually one click of a mouse away. Try applying “Evidence-based decisions in surgery” in your practice. I am convinced you will find them valuable as you make decisions for the most appropriate care of your patients.

 

Dr. Rikkers is Editor in Chief of ACS Surgery News

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Primary care management of persons infected with HIV

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According to the U.S. Preventive Services Task Force, 1.2 million Americans are living with human immunodeficiency virus infection, and there are 50,000 new cases per year. In 20%-25% of those new cases, patients are unaware of having HIV infection. The recommendation for HIV screening by the USPSTF in 2013 is that all patients between 15 and 65 years of age should receive screening. The HIV Medicine Association of the Infectious Diseases Society of America released updated evidence-based guidelines for primary care management of persons infected with HIV.

Initial assessment

The new guidelines emphasize that all new patients who present to the office with an existing HIV infection undergo a comprehensive assessment, including a complete history, physical, and specific testing. The history must include the date of HIV diagnosis and approximate date of infection. Review the patient’s highest viral load, lowest CD4 count, and past and current treatment regimens; and document any history of opportunistic infections or HIV-related comorbidities. Note any chronic medical conditions, such as cardiovascular disease, diabetes mellitus, and/or renal or liver dysfunction that may impact future treatment regimens for HIV. A general discussion of the person’s understanding of their HIV infection may uncover any mental illness, economic burdens, and lack of social support that may present barriers to treatment adherence.

Testing

The guidelines recommend specific testing that should be performed on initial visit and subsequent further monitoring. It is suggested that the CD4 count be documented and the HIV viral load be quantified in patients who already have the diagnosis of HIV infection. In newly diagnosed patients with HIV infection, it is recommended that you get a CD4 cell count, viral load, and HIV genotype/resistance testing to help choose future antiretroviral therapies. The initial assessment should include testing for possible coexisting conditions, including other sexually transmitted infections: gonorrhea, chlamydia, and syphilis. The patient should be screened for hepatitis A, B, and C; toxoplasmosis; CMV; and tuberculosis. TB screening can be done with either the tuberculin skin test or interferon-gamma release assay.

It is also important to establish a baseline fasting comprehensive metabolic panel, complete blood count, urinalysis, creatinine clearance, and fasting lipid panel because HIV infection and certain antiretroviral therapy (ART) can have a negative effect on a range of organ systems.

Immunization and preventive health screening

Immunization should be routine for all patients with HIV infection. In addition to standard recommendations for all adults, the recommendations for patients with HIV include:

• Hepatitis A and hepatitis B vaccines series. Note that for hepatitis B vaccine, the dose is the 40-mcg dose that is used for immunocompromised patients. Patients should be tested for hepatitis A total, or IgG antibody, 1-2 months after the second dose of the HAV vaccine and HBsAb response 1-2 months after the third dose of the HBV vaccine.

• Pneumococcal vaccine. Patients should receive a dose of PCV13 (Prevnar 13), followed by a dose of PPV23 (Pneumovax) at least 8 weeks later. If a patient was previously vaccinated with PPV23, give PCV13 at least 1 year after PPV23.

• Influenza. Annual flu shot should be given.

• Varicella. Administer to HIV-infected persons with a CD4 count greater than 200 cells/mcL who do not have evidence of immunity to varicella.

• HPV. Indicated for females aged 9-26 years and males aged 9-26 years.

Ongoing monitoring

The main tests to follow in a patient with HIV infection to determine if treatment is successful are viral loads and CD4 counts. The viral load should be checked every 3-4 months after initial diagnosis or more frequently when beginning a new regimen. After 2-3 years of being treated and having their viral load successfully suppressed, a patient is considered stable, and the interval of time to test can be extended to every 6 months.

CD4 counts are a useful tool to assess for the need to start ART urgently as well as the effectiveness of ART. If the count drops below certain numbers, the CD4 count can determine the need for prophylactic therapy against opportunistic infections. For CD4 counts in a stable patient who has a suppressed viral load and an adequate CD4 response, the interval of time between monitoring can be extended to every 6-12 months. There are certain metabolic concerns that need frequent monitoring that are associated with the HIV infection itself and the different side effects of specific treatments. Renal function, complete blood count, lipid panel, fasting glucose, hemoglobin A1c, and liver function studies all require frequent monitoring.

Cervical cancer screening is important, and HIV patients are an exception to the newer lengthened screening interval recommendations. Women with HIV infection should have a pap smear at the time of HIV infection diagnosis, repeated at 6 months, then annually thereafter.

 

 

The bottom line

The prognosis of people living with HIV infection continues to improve because of new classes of treatment therapies. HIV infection has become a chronic illness, with which patients can live a long life if they take an active role in their treatment. For this reason, the primary care provider has a vital role in the management of HIV-infected persons. At each visit, the primary care provider should discuss the person’s HIV infection and emphasize the importance of adherence to ART, follow-up visits, and overall participation in their care.

References

Aberg J.A., et al. Primary Care Guidelines for the Management of Persons Infected With HIV: 2013 Update by the HIV Medicine Association of the Infectious Diseases Society of America. IDSA Guidelines 2013, 1-30.

Moyer, V., et al. Screening for HIV: U.S. Preventive Services Task Force Recommendation Statement. Ann. Int. Med., April 30, 2013, 1-10.

Dr. Skolnik is associate director of the family medicine residency program at Abington (Pa.) Memorial Hospital and professor of family and community medicine at Temple University, Philadelphia. Dr. Baranck is a second-year resident and will be one of next year’s chief residents in the Family Medicine Residency Program at Abington Memorial Hospital.

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According to the U.S. Preventive Services Task Force, 1.2 million Americans are living with human immunodeficiency virus infection, and there are 50,000 new cases per year. In 20%-25% of those new cases, patients are unaware of having HIV infection. The recommendation for HIV screening by the USPSTF in 2013 is that all patients between 15 and 65 years of age should receive screening. The HIV Medicine Association of the Infectious Diseases Society of America released updated evidence-based guidelines for primary care management of persons infected with HIV.

Initial assessment

The new guidelines emphasize that all new patients who present to the office with an existing HIV infection undergo a comprehensive assessment, including a complete history, physical, and specific testing. The history must include the date of HIV diagnosis and approximate date of infection. Review the patient’s highest viral load, lowest CD4 count, and past and current treatment regimens; and document any history of opportunistic infections or HIV-related comorbidities. Note any chronic medical conditions, such as cardiovascular disease, diabetes mellitus, and/or renal or liver dysfunction that may impact future treatment regimens for HIV. A general discussion of the person’s understanding of their HIV infection may uncover any mental illness, economic burdens, and lack of social support that may present barriers to treatment adherence.

Testing

The guidelines recommend specific testing that should be performed on initial visit and subsequent further monitoring. It is suggested that the CD4 count be documented and the HIV viral load be quantified in patients who already have the diagnosis of HIV infection. In newly diagnosed patients with HIV infection, it is recommended that you get a CD4 cell count, viral load, and HIV genotype/resistance testing to help choose future antiretroviral therapies. The initial assessment should include testing for possible coexisting conditions, including other sexually transmitted infections: gonorrhea, chlamydia, and syphilis. The patient should be screened for hepatitis A, B, and C; toxoplasmosis; CMV; and tuberculosis. TB screening can be done with either the tuberculin skin test or interferon-gamma release assay.

It is also important to establish a baseline fasting comprehensive metabolic panel, complete blood count, urinalysis, creatinine clearance, and fasting lipid panel because HIV infection and certain antiretroviral therapy (ART) can have a negative effect on a range of organ systems.

Immunization and preventive health screening

Immunization should be routine for all patients with HIV infection. In addition to standard recommendations for all adults, the recommendations for patients with HIV include:

• Hepatitis A and hepatitis B vaccines series. Note that for hepatitis B vaccine, the dose is the 40-mcg dose that is used for immunocompromised patients. Patients should be tested for hepatitis A total, or IgG antibody, 1-2 months after the second dose of the HAV vaccine and HBsAb response 1-2 months after the third dose of the HBV vaccine.

• Pneumococcal vaccine. Patients should receive a dose of PCV13 (Prevnar 13), followed by a dose of PPV23 (Pneumovax) at least 8 weeks later. If a patient was previously vaccinated with PPV23, give PCV13 at least 1 year after PPV23.

• Influenza. Annual flu shot should be given.

• Varicella. Administer to HIV-infected persons with a CD4 count greater than 200 cells/mcL who do not have evidence of immunity to varicella.

• HPV. Indicated for females aged 9-26 years and males aged 9-26 years.

Ongoing monitoring

The main tests to follow in a patient with HIV infection to determine if treatment is successful are viral loads and CD4 counts. The viral load should be checked every 3-4 months after initial diagnosis or more frequently when beginning a new regimen. After 2-3 years of being treated and having their viral load successfully suppressed, a patient is considered stable, and the interval of time to test can be extended to every 6 months.

CD4 counts are a useful tool to assess for the need to start ART urgently as well as the effectiveness of ART. If the count drops below certain numbers, the CD4 count can determine the need for prophylactic therapy against opportunistic infections. For CD4 counts in a stable patient who has a suppressed viral load and an adequate CD4 response, the interval of time between monitoring can be extended to every 6-12 months. There are certain metabolic concerns that need frequent monitoring that are associated with the HIV infection itself and the different side effects of specific treatments. Renal function, complete blood count, lipid panel, fasting glucose, hemoglobin A1c, and liver function studies all require frequent monitoring.

Cervical cancer screening is important, and HIV patients are an exception to the newer lengthened screening interval recommendations. Women with HIV infection should have a pap smear at the time of HIV infection diagnosis, repeated at 6 months, then annually thereafter.

 

 

The bottom line

The prognosis of people living with HIV infection continues to improve because of new classes of treatment therapies. HIV infection has become a chronic illness, with which patients can live a long life if they take an active role in their treatment. For this reason, the primary care provider has a vital role in the management of HIV-infected persons. At each visit, the primary care provider should discuss the person’s HIV infection and emphasize the importance of adherence to ART, follow-up visits, and overall participation in their care.

References

Aberg J.A., et al. Primary Care Guidelines for the Management of Persons Infected With HIV: 2013 Update by the HIV Medicine Association of the Infectious Diseases Society of America. IDSA Guidelines 2013, 1-30.

Moyer, V., et al. Screening for HIV: U.S. Preventive Services Task Force Recommendation Statement. Ann. Int. Med., April 30, 2013, 1-10.

Dr. Skolnik is associate director of the family medicine residency program at Abington (Pa.) Memorial Hospital and professor of family and community medicine at Temple University, Philadelphia. Dr. Baranck is a second-year resident and will be one of next year’s chief residents in the Family Medicine Residency Program at Abington Memorial Hospital.

According to the U.S. Preventive Services Task Force, 1.2 million Americans are living with human immunodeficiency virus infection, and there are 50,000 new cases per year. In 20%-25% of those new cases, patients are unaware of having HIV infection. The recommendation for HIV screening by the USPSTF in 2013 is that all patients between 15 and 65 years of age should receive screening. The HIV Medicine Association of the Infectious Diseases Society of America released updated evidence-based guidelines for primary care management of persons infected with HIV.

Initial assessment

The new guidelines emphasize that all new patients who present to the office with an existing HIV infection undergo a comprehensive assessment, including a complete history, physical, and specific testing. The history must include the date of HIV diagnosis and approximate date of infection. Review the patient’s highest viral load, lowest CD4 count, and past and current treatment regimens; and document any history of opportunistic infections or HIV-related comorbidities. Note any chronic medical conditions, such as cardiovascular disease, diabetes mellitus, and/or renal or liver dysfunction that may impact future treatment regimens for HIV. A general discussion of the person’s understanding of their HIV infection may uncover any mental illness, economic burdens, and lack of social support that may present barriers to treatment adherence.

Testing

The guidelines recommend specific testing that should be performed on initial visit and subsequent further monitoring. It is suggested that the CD4 count be documented and the HIV viral load be quantified in patients who already have the diagnosis of HIV infection. In newly diagnosed patients with HIV infection, it is recommended that you get a CD4 cell count, viral load, and HIV genotype/resistance testing to help choose future antiretroviral therapies. The initial assessment should include testing for possible coexisting conditions, including other sexually transmitted infections: gonorrhea, chlamydia, and syphilis. The patient should be screened for hepatitis A, B, and C; toxoplasmosis; CMV; and tuberculosis. TB screening can be done with either the tuberculin skin test or interferon-gamma release assay.

It is also important to establish a baseline fasting comprehensive metabolic panel, complete blood count, urinalysis, creatinine clearance, and fasting lipid panel because HIV infection and certain antiretroviral therapy (ART) can have a negative effect on a range of organ systems.

Immunization and preventive health screening

Immunization should be routine for all patients with HIV infection. In addition to standard recommendations for all adults, the recommendations for patients with HIV include:

• Hepatitis A and hepatitis B vaccines series. Note that for hepatitis B vaccine, the dose is the 40-mcg dose that is used for immunocompromised patients. Patients should be tested for hepatitis A total, or IgG antibody, 1-2 months after the second dose of the HAV vaccine and HBsAb response 1-2 months after the third dose of the HBV vaccine.

• Pneumococcal vaccine. Patients should receive a dose of PCV13 (Prevnar 13), followed by a dose of PPV23 (Pneumovax) at least 8 weeks later. If a patient was previously vaccinated with PPV23, give PCV13 at least 1 year after PPV23.

• Influenza. Annual flu shot should be given.

• Varicella. Administer to HIV-infected persons with a CD4 count greater than 200 cells/mcL who do not have evidence of immunity to varicella.

• HPV. Indicated for females aged 9-26 years and males aged 9-26 years.

Ongoing monitoring

The main tests to follow in a patient with HIV infection to determine if treatment is successful are viral loads and CD4 counts. The viral load should be checked every 3-4 months after initial diagnosis or more frequently when beginning a new regimen. After 2-3 years of being treated and having their viral load successfully suppressed, a patient is considered stable, and the interval of time to test can be extended to every 6 months.

CD4 counts are a useful tool to assess for the need to start ART urgently as well as the effectiveness of ART. If the count drops below certain numbers, the CD4 count can determine the need for prophylactic therapy against opportunistic infections. For CD4 counts in a stable patient who has a suppressed viral load and an adequate CD4 response, the interval of time between monitoring can be extended to every 6-12 months. There are certain metabolic concerns that need frequent monitoring that are associated with the HIV infection itself and the different side effects of specific treatments. Renal function, complete blood count, lipid panel, fasting glucose, hemoglobin A1c, and liver function studies all require frequent monitoring.

Cervical cancer screening is important, and HIV patients are an exception to the newer lengthened screening interval recommendations. Women with HIV infection should have a pap smear at the time of HIV infection diagnosis, repeated at 6 months, then annually thereafter.

 

 

The bottom line

The prognosis of people living with HIV infection continues to improve because of new classes of treatment therapies. HIV infection has become a chronic illness, with which patients can live a long life if they take an active role in their treatment. For this reason, the primary care provider has a vital role in the management of HIV-infected persons. At each visit, the primary care provider should discuss the person’s HIV infection and emphasize the importance of adherence to ART, follow-up visits, and overall participation in their care.

References

Aberg J.A., et al. Primary Care Guidelines for the Management of Persons Infected With HIV: 2013 Update by the HIV Medicine Association of the Infectious Diseases Society of America. IDSA Guidelines 2013, 1-30.

Moyer, V., et al. Screening for HIV: U.S. Preventive Services Task Force Recommendation Statement. Ann. Int. Med., April 30, 2013, 1-10.

Dr. Skolnik is associate director of the family medicine residency program at Abington (Pa.) Memorial Hospital and professor of family and community medicine at Temple University, Philadelphia. Dr. Baranck is a second-year resident and will be one of next year’s chief residents in the Family Medicine Residency Program at Abington Memorial Hospital.

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Simplicity of ‘Neighbor Rosicky’ keeps the doctor in me going

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Simplicity of ‘Neighbor Rosicky’ keeps the doctor in me going

How often have you read "Neighbor Rosicky" by Willa Cather?

Really? You should. It’ll take maybe an hour, at most. You can likely find it free online.

It was an assignment for a college literature class I took in 1987. A lot of the things we read weren’t particularly memorable, but this one grabbed me. It’s a simple story about life, aging, and family, partially told through the eyes of a young doctor. At the same time it has both very little and a lot to do with being a doctor. It wasn’t my sole inspiration to become one, but it struck a chord that made me feel like it was the right thing for me.

At its heart and soul, it’s why, I believe, many of us become doctors. In the modern era, it’s also likely more fantasy than reality. But the basic theme is there: helping patients who genuinely need you and who appreciate what you do for them, even when the news isn’t good.

I’m sure there are still areas (though not many in the Western world) where medicine is more like the story. Besides, neurology is a pretty tech-dependent field. We couldn’t do our job without advanced imaging, electroencephalography, electromyography and nerve conduction velocity testing, etc.

But we still care for patients. For all the labels that get put on us (practitioners, providers, defendants, etc.) what we do now is still what the shamans did ages ago: try to help sick people with the tools that are available to us. And that, at the center of things, is what being a doctor is about.

It’s an idea that’s easy to lose sight of these days, with the endless forms for medication and test authorizations; news articles about how we’re overpaid, underpaid, inebriated, suicidal, or dangerous; and where there’s an emphasis on patient satisfaction that doesn’t necessarily involve clinical outcomes ("my migraines are better, but I was disappointed I wasn’t offered a beverage while waiting for the doctor").

So, I keep a copy of "Neighbor Rosicky" on my Kindle, and read it when I need to remind myself why I like this job. Sometimes even grateful patients forget to say thank you, and it’s good to remember that we are, for the most part, appreciated.

Dr. Block has a solo neurology practice in Scottsdale, Ariz.

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How often have you read "Neighbor Rosicky" by Willa Cather?

Really? You should. It’ll take maybe an hour, at most. You can likely find it free online.

It was an assignment for a college literature class I took in 1987. A lot of the things we read weren’t particularly memorable, but this one grabbed me. It’s a simple story about life, aging, and family, partially told through the eyes of a young doctor. At the same time it has both very little and a lot to do with being a doctor. It wasn’t my sole inspiration to become one, but it struck a chord that made me feel like it was the right thing for me.

At its heart and soul, it’s why, I believe, many of us become doctors. In the modern era, it’s also likely more fantasy than reality. But the basic theme is there: helping patients who genuinely need you and who appreciate what you do for them, even when the news isn’t good.

I’m sure there are still areas (though not many in the Western world) where medicine is more like the story. Besides, neurology is a pretty tech-dependent field. We couldn’t do our job without advanced imaging, electroencephalography, electromyography and nerve conduction velocity testing, etc.

But we still care for patients. For all the labels that get put on us (practitioners, providers, defendants, etc.) what we do now is still what the shamans did ages ago: try to help sick people with the tools that are available to us. And that, at the center of things, is what being a doctor is about.

It’s an idea that’s easy to lose sight of these days, with the endless forms for medication and test authorizations; news articles about how we’re overpaid, underpaid, inebriated, suicidal, or dangerous; and where there’s an emphasis on patient satisfaction that doesn’t necessarily involve clinical outcomes ("my migraines are better, but I was disappointed I wasn’t offered a beverage while waiting for the doctor").

So, I keep a copy of "Neighbor Rosicky" on my Kindle, and read it when I need to remind myself why I like this job. Sometimes even grateful patients forget to say thank you, and it’s good to remember that we are, for the most part, appreciated.

Dr. Block has a solo neurology practice in Scottsdale, Ariz.

How often have you read "Neighbor Rosicky" by Willa Cather?

Really? You should. It’ll take maybe an hour, at most. You can likely find it free online.

It was an assignment for a college literature class I took in 1987. A lot of the things we read weren’t particularly memorable, but this one grabbed me. It’s a simple story about life, aging, and family, partially told through the eyes of a young doctor. At the same time it has both very little and a lot to do with being a doctor. It wasn’t my sole inspiration to become one, but it struck a chord that made me feel like it was the right thing for me.

At its heart and soul, it’s why, I believe, many of us become doctors. In the modern era, it’s also likely more fantasy than reality. But the basic theme is there: helping patients who genuinely need you and who appreciate what you do for them, even when the news isn’t good.

I’m sure there are still areas (though not many in the Western world) where medicine is more like the story. Besides, neurology is a pretty tech-dependent field. We couldn’t do our job without advanced imaging, electroencephalography, electromyography and nerve conduction velocity testing, etc.

But we still care for patients. For all the labels that get put on us (practitioners, providers, defendants, etc.) what we do now is still what the shamans did ages ago: try to help sick people with the tools that are available to us. And that, at the center of things, is what being a doctor is about.

It’s an idea that’s easy to lose sight of these days, with the endless forms for medication and test authorizations; news articles about how we’re overpaid, underpaid, inebriated, suicidal, or dangerous; and where there’s an emphasis on patient satisfaction that doesn’t necessarily involve clinical outcomes ("my migraines are better, but I was disappointed I wasn’t offered a beverage while waiting for the doctor").

So, I keep a copy of "Neighbor Rosicky" on my Kindle, and read it when I need to remind myself why I like this job. Sometimes even grateful patients forget to say thank you, and it’s good to remember that we are, for the most part, appreciated.

Dr. Block has a solo neurology practice in Scottsdale, Ariz.

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Oppositional behavior

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Oppositional behavior

Introduction

All children learn to say "no" and want to experiment with asserting their will, but children who frequently refuse to comply are extremely challenging, making oppositional behavior one of the most common presentations to pediatricians and child psychiatrists.

 

 

Dr. Allison Hall

Case summary

A 4-and-a-half-year-old boy whose parents have been divorced for 2 years presents with a 2-year history of aggression toward other kids in day care, biting and kicking, and tantrums and defiance when he doesn’t want to do something, especially transition from one activity to another. These episodes are brief but have been increasing in frequency and severity, and recently, he has been hitting his mother when it is time to leave the playground. His parents have tried reasoning with him, providing warnings, time-outs, and counting to 3. "Nothing works." He argues constantly and gets irritable easily. He also has a high energy level and short attention span and sometimes gets anxious over small issues.

Discussion

Psychologists who systematically observe families that struggle with this kind of behavior often see a cycle of child refusal and parental frustration and desperate attempts to force the child to comply by finding the right punishment. Parents often repeat their instructions over and over without success, getting increasingly frustrated, sometimes yelling or hitting. When parents achieve success after yelling, they may end up thinking that it is only verbal, or even physical, aggression that will force the child to comply. Parents may also give up at other times, teaching the child that sometimes their refusals will help him to avoid a task. There can be gradual escalation in tantrums, yelling, or physical aggression on the part of both parents and the child over the years.

There are often underlying aspects of the child’s temperament and genetic make-up that contribute to this cycle. Aspects of temperament such as difficulties with transitions to new activities, quick negative emotional responses, and stubbornness contribute. Attention deficit/hyperactivity disorder (ADHD) and language difficulties are also common factors. Parents’ own personalities, emotional, and behavioral issues, and outside stressors affecting the family also increase the chance of entering this distressing cycle. In this case, the child’s behavior seemed to start or worsen after the stressor of the divorce, and he has some symptoms suggestive of ADHD as well as irritability and anxiety, which might be an adjustment response to the divorce, an aspect of his temperament, or a more clinical mood disorder.

When facing a complex picture such as this, it can be helpful to obtain general behavioral rating scales such as the Child Behavior Checklist (CBCL) or Behavior Assessment System for Children (BASC) from parents and teachers to assess how severe differing components of the presentation are in comparison to other children of the same age and sex. Developmental assessments including information from schools can help clarify cognitive and language issues that may play a role

In addition to addressing any underlying issues, the intervention best supported by evidence is training parents in behavioral skills to address the oppositional and impulsive behavior. Teaching parents specific skills to notice and reinforce good behaviors while decreasing reinforcement for bad behaviors improves the relationship and motivates children to behave better. The second part of this type of program involves replacing yelling and harsh punishments with mild consequences that are delivered calmly and very consistently.

These skills may sound simple but can be challenging to put in place. Specific programs that give parents abundant opportunities to practice and master the skills through practice with their child in session and role plays have repeatedly been demonstrated to improve compliance and relationships with the child. Specific, very-well-researched programs include Helping the Noncompliant Child, Parent Child Interaction Therapy, The Incredible Years, Triple P, Parent Management Training Oregon, Parent Management Training (Kazdin), and The Defiant Teen and The Defiant Child.

It can sometimes be difficult to find therapists experienced with these programs. It is worth inquiring about the specific programs therapists use or even encouraging therapists to get trained in a specific program. Manuals are readily available for Helping the Noncompliant Child, Parent Management Training (Kazdin), and The Defiant Child and The Defiant Teen among others. The Yale Parenting Center offers online or phone consultation. Information about training in all of the above programs is available online.

How we talk to parents about the complex factors that play into oppositional behavior sets the stage for treatment. Parents often feel overwhelmed, guilty, and defensive. I stress that the difficulties do not originate with the parent but are a mix of the stresses the family experiences, the child’s temperament and genetic make-up, and the parent’s own temperament, and parenting style. I emphasize how challenging children can be and that it is not obvious how to respond to these behaviors. And I stress that we want to address the issue in as many ways as we can and that parents are the most important people in their children’s lives. In the end, such programs often help parents feel empowered and closer to their children.

 

 

Dr. Hall is an assistant professor of psychiatry and pediatrics at the University of Vermont, Burlington. She provides periodic trainings in Helping the Noncompliant Child and the use of the manual Parent Management Training by Alan Kazdin but has no financial conflicts relevant to this article.

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Introduction

All children learn to say "no" and want to experiment with asserting their will, but children who frequently refuse to comply are extremely challenging, making oppositional behavior one of the most common presentations to pediatricians and child psychiatrists.

 

 

Dr. Allison Hall

Case summary

A 4-and-a-half-year-old boy whose parents have been divorced for 2 years presents with a 2-year history of aggression toward other kids in day care, biting and kicking, and tantrums and defiance when he doesn’t want to do something, especially transition from one activity to another. These episodes are brief but have been increasing in frequency and severity, and recently, he has been hitting his mother when it is time to leave the playground. His parents have tried reasoning with him, providing warnings, time-outs, and counting to 3. "Nothing works." He argues constantly and gets irritable easily. He also has a high energy level and short attention span and sometimes gets anxious over small issues.

Discussion

Psychologists who systematically observe families that struggle with this kind of behavior often see a cycle of child refusal and parental frustration and desperate attempts to force the child to comply by finding the right punishment. Parents often repeat their instructions over and over without success, getting increasingly frustrated, sometimes yelling or hitting. When parents achieve success after yelling, they may end up thinking that it is only verbal, or even physical, aggression that will force the child to comply. Parents may also give up at other times, teaching the child that sometimes their refusals will help him to avoid a task. There can be gradual escalation in tantrums, yelling, or physical aggression on the part of both parents and the child over the years.

There are often underlying aspects of the child’s temperament and genetic make-up that contribute to this cycle. Aspects of temperament such as difficulties with transitions to new activities, quick negative emotional responses, and stubbornness contribute. Attention deficit/hyperactivity disorder (ADHD) and language difficulties are also common factors. Parents’ own personalities, emotional, and behavioral issues, and outside stressors affecting the family also increase the chance of entering this distressing cycle. In this case, the child’s behavior seemed to start or worsen after the stressor of the divorce, and he has some symptoms suggestive of ADHD as well as irritability and anxiety, which might be an adjustment response to the divorce, an aspect of his temperament, or a more clinical mood disorder.

When facing a complex picture such as this, it can be helpful to obtain general behavioral rating scales such as the Child Behavior Checklist (CBCL) or Behavior Assessment System for Children (BASC) from parents and teachers to assess how severe differing components of the presentation are in comparison to other children of the same age and sex. Developmental assessments including information from schools can help clarify cognitive and language issues that may play a role

In addition to addressing any underlying issues, the intervention best supported by evidence is training parents in behavioral skills to address the oppositional and impulsive behavior. Teaching parents specific skills to notice and reinforce good behaviors while decreasing reinforcement for bad behaviors improves the relationship and motivates children to behave better. The second part of this type of program involves replacing yelling and harsh punishments with mild consequences that are delivered calmly and very consistently.

These skills may sound simple but can be challenging to put in place. Specific programs that give parents abundant opportunities to practice and master the skills through practice with their child in session and role plays have repeatedly been demonstrated to improve compliance and relationships with the child. Specific, very-well-researched programs include Helping the Noncompliant Child, Parent Child Interaction Therapy, The Incredible Years, Triple P, Parent Management Training Oregon, Parent Management Training (Kazdin), and The Defiant Teen and The Defiant Child.

It can sometimes be difficult to find therapists experienced with these programs. It is worth inquiring about the specific programs therapists use or even encouraging therapists to get trained in a specific program. Manuals are readily available for Helping the Noncompliant Child, Parent Management Training (Kazdin), and The Defiant Child and The Defiant Teen among others. The Yale Parenting Center offers online or phone consultation. Information about training in all of the above programs is available online.

How we talk to parents about the complex factors that play into oppositional behavior sets the stage for treatment. Parents often feel overwhelmed, guilty, and defensive. I stress that the difficulties do not originate with the parent but are a mix of the stresses the family experiences, the child’s temperament and genetic make-up, and the parent’s own temperament, and parenting style. I emphasize how challenging children can be and that it is not obvious how to respond to these behaviors. And I stress that we want to address the issue in as many ways as we can and that parents are the most important people in their children’s lives. In the end, such programs often help parents feel empowered and closer to their children.

 

 

Dr. Hall is an assistant professor of psychiatry and pediatrics at the University of Vermont, Burlington. She provides periodic trainings in Helping the Noncompliant Child and the use of the manual Parent Management Training by Alan Kazdin but has no financial conflicts relevant to this article.

Introduction

All children learn to say "no" and want to experiment with asserting their will, but children who frequently refuse to comply are extremely challenging, making oppositional behavior one of the most common presentations to pediatricians and child psychiatrists.

 

 

Dr. Allison Hall

Case summary

A 4-and-a-half-year-old boy whose parents have been divorced for 2 years presents with a 2-year history of aggression toward other kids in day care, biting and kicking, and tantrums and defiance when he doesn’t want to do something, especially transition from one activity to another. These episodes are brief but have been increasing in frequency and severity, and recently, he has been hitting his mother when it is time to leave the playground. His parents have tried reasoning with him, providing warnings, time-outs, and counting to 3. "Nothing works." He argues constantly and gets irritable easily. He also has a high energy level and short attention span and sometimes gets anxious over small issues.

Discussion

Psychologists who systematically observe families that struggle with this kind of behavior often see a cycle of child refusal and parental frustration and desperate attempts to force the child to comply by finding the right punishment. Parents often repeat their instructions over and over without success, getting increasingly frustrated, sometimes yelling or hitting. When parents achieve success after yelling, they may end up thinking that it is only verbal, or even physical, aggression that will force the child to comply. Parents may also give up at other times, teaching the child that sometimes their refusals will help him to avoid a task. There can be gradual escalation in tantrums, yelling, or physical aggression on the part of both parents and the child over the years.

There are often underlying aspects of the child’s temperament and genetic make-up that contribute to this cycle. Aspects of temperament such as difficulties with transitions to new activities, quick negative emotional responses, and stubbornness contribute. Attention deficit/hyperactivity disorder (ADHD) and language difficulties are also common factors. Parents’ own personalities, emotional, and behavioral issues, and outside stressors affecting the family also increase the chance of entering this distressing cycle. In this case, the child’s behavior seemed to start or worsen after the stressor of the divorce, and he has some symptoms suggestive of ADHD as well as irritability and anxiety, which might be an adjustment response to the divorce, an aspect of his temperament, or a more clinical mood disorder.

When facing a complex picture such as this, it can be helpful to obtain general behavioral rating scales such as the Child Behavior Checklist (CBCL) or Behavior Assessment System for Children (BASC) from parents and teachers to assess how severe differing components of the presentation are in comparison to other children of the same age and sex. Developmental assessments including information from schools can help clarify cognitive and language issues that may play a role

In addition to addressing any underlying issues, the intervention best supported by evidence is training parents in behavioral skills to address the oppositional and impulsive behavior. Teaching parents specific skills to notice and reinforce good behaviors while decreasing reinforcement for bad behaviors improves the relationship and motivates children to behave better. The second part of this type of program involves replacing yelling and harsh punishments with mild consequences that are delivered calmly and very consistently.

These skills may sound simple but can be challenging to put in place. Specific programs that give parents abundant opportunities to practice and master the skills through practice with their child in session and role plays have repeatedly been demonstrated to improve compliance and relationships with the child. Specific, very-well-researched programs include Helping the Noncompliant Child, Parent Child Interaction Therapy, The Incredible Years, Triple P, Parent Management Training Oregon, Parent Management Training (Kazdin), and The Defiant Teen and The Defiant Child.

It can sometimes be difficult to find therapists experienced with these programs. It is worth inquiring about the specific programs therapists use or even encouraging therapists to get trained in a specific program. Manuals are readily available for Helping the Noncompliant Child, Parent Management Training (Kazdin), and The Defiant Child and The Defiant Teen among others. The Yale Parenting Center offers online or phone consultation. Information about training in all of the above programs is available online.

How we talk to parents about the complex factors that play into oppositional behavior sets the stage for treatment. Parents often feel overwhelmed, guilty, and defensive. I stress that the difficulties do not originate with the parent but are a mix of the stresses the family experiences, the child’s temperament and genetic make-up, and the parent’s own temperament, and parenting style. I emphasize how challenging children can be and that it is not obvious how to respond to these behaviors. And I stress that we want to address the issue in as many ways as we can and that parents are the most important people in their children’s lives. In the end, such programs often help parents feel empowered and closer to their children.

 

 

Dr. Hall is an assistant professor of psychiatry and pediatrics at the University of Vermont, Burlington. She provides periodic trainings in Helping the Noncompliant Child and the use of the manual Parent Management Training by Alan Kazdin but has no financial conflicts relevant to this article.

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Bellis perennis

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Known also as the common daisy or English daisy, Bellis perennis is a perennial plant belonging to the Asteraceae or Compositae (aster, daisy, or sunflower) family. Native to Europe and North Africa, it has been used in traditional medicine in Europe since the Middle Ages to treat bruises, broken bones, muscle pain, cutaneous wounds, and rheumatism. Other skin applications include eczema, boils, inflammation, and purulent skin disease. In addition, B. perennis has been used in folk medicine to treat upper respiratory tract infections, gastritis, stomachache, diarrhea, bleeding, rheumatism, common colds, and headache (Pharm. Biol. 2014 March 12 [Epub ahead of print]; Pharm. Biol. 2012;50:1031-7; Chem. Pharm. Bull. [Tokyo] 2008;56:559-68; Chem. Pharm. Bull. [Tokyo] 2011;59:889-95; Lim, T.K. Edible Medicinal and Non-Medicinal Plants. Springer: Dordrecht, 2014, pp. 204-11).

Chemistry

Courtesy Wikimedia Commons/Gareth Davidson Bitplane/Creative Commons License
English daisies have been used throughout history to treat a variety of diseases.

B. perennis roots and flowers have been shown to contain several important bioactive constituents, including triterpene saponins, anthocyanins, flavonoids, polysaccharides, and polyacetylenes (Chem. Pharm. Bull. [Tokyo] 2008;56:559-68; SOFW J. 2005;131:40-9). In 2008, Morikawa et al. identified newly isolated triterpene saponins in B. perennis. These compounds, labeled as perennisosides I-VII, exhibited inhibitory activity on serum triglyceride elevation in olive oil–treated mice (J. Nat. Prod. 2008;71:828-35). That same year, Yoshikawa et al. isolated six new acylated oleanane-type triterpene oligoglycosides (perennisaponins A-F) from the flowers of B. perennis in addition to 14 saponins, 9 flavonoids, and 2 glycosides (Chem. Pharm. Bull. [Tokyo] 2008;56:559-68).

In 2011, Morikawa et al. isolated five new triterpene saponins (perennisosides VIII-XII) from the methanolic extract of B. perennis flowers. The extract was shown to suppress gastric emptying in olive oil–laded mice (Chem. Pharm. Bull. [Tokyo] 2011;59:889-95).

Early in 2014, Pehlivan et al. used bioassay-guided fractionation and isolation procedures to isolate an oleanane-type saponin from B. perennis that exhibited antitumor activity, the first such finding associated with B. perennis flowers. Tumor inhibition of 99% was achieved by the most active fraction at 3,000 mg/L (Pharm. Biol. 2014 March 12 [Epub ahead of print]).

Wound-healing capacity

In 2012, Karakas et al. studied the wound-healing activity displayed by the dried flowers of B. perennis in 12 male adult Wistar albino rats over a 30-day period. Six wounds were introduced onto each animal, with two treated topically once a day with a hydrophilic ointment containing an n-butanol fraction of B. perennis, two treated daily with the ointment minus the B. perennis fraction, and two untreated wounds used as control. Statistically significant differences were noted with 100% wound closure in the B. perennis group, 87% in the control group, and 85% in the other treatment group. The investigators concluded that their findings represented the first scientific confirmation supporting the traditional usage of B. perennis for wound healing. They noted that the topical administration of an ointment formulated with an n-butanol fraction of B. perennis flowers exhibits wound healing activity without inducing scars in a circular excision wound model in rats (Pharm. Biol. 2012;50:1031-7).

Antimicrobial activity against gram-positive and gram-negative bacteria, as well as anticancer activity against human leukemia cells in vitro, has also been associated with B. perennis (Lim, T.K. Edible Medicinal and Non-Medicinal Plants. Springer: Dordrecht, 2014, pp. 204-11).

Skin-lightening activity

Extracts of B. perennis are included in the product Belides that has been combined in a formulation with emblica and licorice for use as a skin-lightening agent. In 2010, Costa et al. conducted a monoblind clinical study to assess the clinical efficacy of the combination of Belides, emblica, and licorice 7%, compared with hydroquinone 2% for the treatment of epidermal or mixed melasma in 56 women aged 18-60 years. Subjects (ranging from Fitzpatrick skin type I to IV) exclusively used an SPF 35 sunscreen for 60 days before being selected for either the herbal combination cream treatment, applied twice daily, or the hydroquinone group, applied nightly.

Depigmentation was observed in 78.3% of the herbal combination group and 88.9% of the hydroquinone group, among the 23 volunteers in the herbal group and 27 in the hydroquinone group who completed the study. No statistically significant differences were found between the treatment regimens in ameliorating melasma, but fewer adverse cutaneous reactions were associated with the herbal treatment. The investigators found the combination of Belides, emblica, and licorice to be a safe and effective option for treating melasma (An. Bras. Dermatol. 2010;85:613-20). Previously, Belides was shown to be nearly twice as active as arbutin and an effective skin-lightening agent in a pilot study with human volunteers (SOFW J. 2005;131:40-9; Lim, T.K. Edible Medicinal and Non-Medicinal Plants. Springer: Dordrecht, 2014, pp. 204-11).

 

 

Conclusion

The roots and flowers of B. perennis have been used for many years in traditional medicine to treat various conditions, including skin disorders. While modern scientific interest has been piqued, the current body of evidence is meager. Much more research is necessary to determine the potential role of topical B. perennis in the dermatologic armamentarium. But recent data and the history of traditional use suggest that such research is warranted.

Dr. Baumann is chief executive officer of the Baumann Cosmetic & Research Institute in Miami Beach. She founded the cosmetic dermatology center at the University of Miami in 1997. Dr. Baumann wrote the textbook "Cosmetic Dermatology: Principles and Practice" (McGraw-Hill, April 2002), and a book for consumers, "The Skin Type Solution" (Bantam, 2006). She has contributed to the Cosmeceutical Critique column in Skin & Allergy News since January 2001 and joined the editorial advisory board in 2004. Dr. Baumann has received funding for clinical grants from Allergan, Aveeno, Avon Products, Galderma, Mary Kay, Medicis Pharmaceuticals, Neutrogena, Philosophy, Stiefel, Topix Pharmaceuticals, and Unilever.

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Known also as the common daisy or English daisy, Bellis perennis is a perennial plant belonging to the Asteraceae or Compositae (aster, daisy, or sunflower) family. Native to Europe and North Africa, it has been used in traditional medicine in Europe since the Middle Ages to treat bruises, broken bones, muscle pain, cutaneous wounds, and rheumatism. Other skin applications include eczema, boils, inflammation, and purulent skin disease. In addition, B. perennis has been used in folk medicine to treat upper respiratory tract infections, gastritis, stomachache, diarrhea, bleeding, rheumatism, common colds, and headache (Pharm. Biol. 2014 March 12 [Epub ahead of print]; Pharm. Biol. 2012;50:1031-7; Chem. Pharm. Bull. [Tokyo] 2008;56:559-68; Chem. Pharm. Bull. [Tokyo] 2011;59:889-95; Lim, T.K. Edible Medicinal and Non-Medicinal Plants. Springer: Dordrecht, 2014, pp. 204-11).

Chemistry

Courtesy Wikimedia Commons/Gareth Davidson Bitplane/Creative Commons License
English daisies have been used throughout history to treat a variety of diseases.

B. perennis roots and flowers have been shown to contain several important bioactive constituents, including triterpene saponins, anthocyanins, flavonoids, polysaccharides, and polyacetylenes (Chem. Pharm. Bull. [Tokyo] 2008;56:559-68; SOFW J. 2005;131:40-9). In 2008, Morikawa et al. identified newly isolated triterpene saponins in B. perennis. These compounds, labeled as perennisosides I-VII, exhibited inhibitory activity on serum triglyceride elevation in olive oil–treated mice (J. Nat. Prod. 2008;71:828-35). That same year, Yoshikawa et al. isolated six new acylated oleanane-type triterpene oligoglycosides (perennisaponins A-F) from the flowers of B. perennis in addition to 14 saponins, 9 flavonoids, and 2 glycosides (Chem. Pharm. Bull. [Tokyo] 2008;56:559-68).

In 2011, Morikawa et al. isolated five new triterpene saponins (perennisosides VIII-XII) from the methanolic extract of B. perennis flowers. The extract was shown to suppress gastric emptying in olive oil–laded mice (Chem. Pharm. Bull. [Tokyo] 2011;59:889-95).

Early in 2014, Pehlivan et al. used bioassay-guided fractionation and isolation procedures to isolate an oleanane-type saponin from B. perennis that exhibited antitumor activity, the first such finding associated with B. perennis flowers. Tumor inhibition of 99% was achieved by the most active fraction at 3,000 mg/L (Pharm. Biol. 2014 March 12 [Epub ahead of print]).

Wound-healing capacity

In 2012, Karakas et al. studied the wound-healing activity displayed by the dried flowers of B. perennis in 12 male adult Wistar albino rats over a 30-day period. Six wounds were introduced onto each animal, with two treated topically once a day with a hydrophilic ointment containing an n-butanol fraction of B. perennis, two treated daily with the ointment minus the B. perennis fraction, and two untreated wounds used as control. Statistically significant differences were noted with 100% wound closure in the B. perennis group, 87% in the control group, and 85% in the other treatment group. The investigators concluded that their findings represented the first scientific confirmation supporting the traditional usage of B. perennis for wound healing. They noted that the topical administration of an ointment formulated with an n-butanol fraction of B. perennis flowers exhibits wound healing activity without inducing scars in a circular excision wound model in rats (Pharm. Biol. 2012;50:1031-7).

Antimicrobial activity against gram-positive and gram-negative bacteria, as well as anticancer activity against human leukemia cells in vitro, has also been associated with B. perennis (Lim, T.K. Edible Medicinal and Non-Medicinal Plants. Springer: Dordrecht, 2014, pp. 204-11).

Skin-lightening activity

Extracts of B. perennis are included in the product Belides that has been combined in a formulation with emblica and licorice for use as a skin-lightening agent. In 2010, Costa et al. conducted a monoblind clinical study to assess the clinical efficacy of the combination of Belides, emblica, and licorice 7%, compared with hydroquinone 2% for the treatment of epidermal or mixed melasma in 56 women aged 18-60 years. Subjects (ranging from Fitzpatrick skin type I to IV) exclusively used an SPF 35 sunscreen for 60 days before being selected for either the herbal combination cream treatment, applied twice daily, or the hydroquinone group, applied nightly.

Depigmentation was observed in 78.3% of the herbal combination group and 88.9% of the hydroquinone group, among the 23 volunteers in the herbal group and 27 in the hydroquinone group who completed the study. No statistically significant differences were found between the treatment regimens in ameliorating melasma, but fewer adverse cutaneous reactions were associated with the herbal treatment. The investigators found the combination of Belides, emblica, and licorice to be a safe and effective option for treating melasma (An. Bras. Dermatol. 2010;85:613-20). Previously, Belides was shown to be nearly twice as active as arbutin and an effective skin-lightening agent in a pilot study with human volunteers (SOFW J. 2005;131:40-9; Lim, T.K. Edible Medicinal and Non-Medicinal Plants. Springer: Dordrecht, 2014, pp. 204-11).

 

 

Conclusion

The roots and flowers of B. perennis have been used for many years in traditional medicine to treat various conditions, including skin disorders. While modern scientific interest has been piqued, the current body of evidence is meager. Much more research is necessary to determine the potential role of topical B. perennis in the dermatologic armamentarium. But recent data and the history of traditional use suggest that such research is warranted.

Dr. Baumann is chief executive officer of the Baumann Cosmetic & Research Institute in Miami Beach. She founded the cosmetic dermatology center at the University of Miami in 1997. Dr. Baumann wrote the textbook "Cosmetic Dermatology: Principles and Practice" (McGraw-Hill, April 2002), and a book for consumers, "The Skin Type Solution" (Bantam, 2006). She has contributed to the Cosmeceutical Critique column in Skin & Allergy News since January 2001 and joined the editorial advisory board in 2004. Dr. Baumann has received funding for clinical grants from Allergan, Aveeno, Avon Products, Galderma, Mary Kay, Medicis Pharmaceuticals, Neutrogena, Philosophy, Stiefel, Topix Pharmaceuticals, and Unilever.

Known also as the common daisy or English daisy, Bellis perennis is a perennial plant belonging to the Asteraceae or Compositae (aster, daisy, or sunflower) family. Native to Europe and North Africa, it has been used in traditional medicine in Europe since the Middle Ages to treat bruises, broken bones, muscle pain, cutaneous wounds, and rheumatism. Other skin applications include eczema, boils, inflammation, and purulent skin disease. In addition, B. perennis has been used in folk medicine to treat upper respiratory tract infections, gastritis, stomachache, diarrhea, bleeding, rheumatism, common colds, and headache (Pharm. Biol. 2014 March 12 [Epub ahead of print]; Pharm. Biol. 2012;50:1031-7; Chem. Pharm. Bull. [Tokyo] 2008;56:559-68; Chem. Pharm. Bull. [Tokyo] 2011;59:889-95; Lim, T.K. Edible Medicinal and Non-Medicinal Plants. Springer: Dordrecht, 2014, pp. 204-11).

Chemistry

Courtesy Wikimedia Commons/Gareth Davidson Bitplane/Creative Commons License
English daisies have been used throughout history to treat a variety of diseases.

B. perennis roots and flowers have been shown to contain several important bioactive constituents, including triterpene saponins, anthocyanins, flavonoids, polysaccharides, and polyacetylenes (Chem. Pharm. Bull. [Tokyo] 2008;56:559-68; SOFW J. 2005;131:40-9). In 2008, Morikawa et al. identified newly isolated triterpene saponins in B. perennis. These compounds, labeled as perennisosides I-VII, exhibited inhibitory activity on serum triglyceride elevation in olive oil–treated mice (J. Nat. Prod. 2008;71:828-35). That same year, Yoshikawa et al. isolated six new acylated oleanane-type triterpene oligoglycosides (perennisaponins A-F) from the flowers of B. perennis in addition to 14 saponins, 9 flavonoids, and 2 glycosides (Chem. Pharm. Bull. [Tokyo] 2008;56:559-68).

In 2011, Morikawa et al. isolated five new triterpene saponins (perennisosides VIII-XII) from the methanolic extract of B. perennis flowers. The extract was shown to suppress gastric emptying in olive oil–laded mice (Chem. Pharm. Bull. [Tokyo] 2011;59:889-95).

Early in 2014, Pehlivan et al. used bioassay-guided fractionation and isolation procedures to isolate an oleanane-type saponin from B. perennis that exhibited antitumor activity, the first such finding associated with B. perennis flowers. Tumor inhibition of 99% was achieved by the most active fraction at 3,000 mg/L (Pharm. Biol. 2014 March 12 [Epub ahead of print]).

Wound-healing capacity

In 2012, Karakas et al. studied the wound-healing activity displayed by the dried flowers of B. perennis in 12 male adult Wistar albino rats over a 30-day period. Six wounds were introduced onto each animal, with two treated topically once a day with a hydrophilic ointment containing an n-butanol fraction of B. perennis, two treated daily with the ointment minus the B. perennis fraction, and two untreated wounds used as control. Statistically significant differences were noted with 100% wound closure in the B. perennis group, 87% in the control group, and 85% in the other treatment group. The investigators concluded that their findings represented the first scientific confirmation supporting the traditional usage of B. perennis for wound healing. They noted that the topical administration of an ointment formulated with an n-butanol fraction of B. perennis flowers exhibits wound healing activity without inducing scars in a circular excision wound model in rats (Pharm. Biol. 2012;50:1031-7).

Antimicrobial activity against gram-positive and gram-negative bacteria, as well as anticancer activity against human leukemia cells in vitro, has also been associated with B. perennis (Lim, T.K. Edible Medicinal and Non-Medicinal Plants. Springer: Dordrecht, 2014, pp. 204-11).

Skin-lightening activity

Extracts of B. perennis are included in the product Belides that has been combined in a formulation with emblica and licorice for use as a skin-lightening agent. In 2010, Costa et al. conducted a monoblind clinical study to assess the clinical efficacy of the combination of Belides, emblica, and licorice 7%, compared with hydroquinone 2% for the treatment of epidermal or mixed melasma in 56 women aged 18-60 years. Subjects (ranging from Fitzpatrick skin type I to IV) exclusively used an SPF 35 sunscreen for 60 days before being selected for either the herbal combination cream treatment, applied twice daily, or the hydroquinone group, applied nightly.

Depigmentation was observed in 78.3% of the herbal combination group and 88.9% of the hydroquinone group, among the 23 volunteers in the herbal group and 27 in the hydroquinone group who completed the study. No statistically significant differences were found between the treatment regimens in ameliorating melasma, but fewer adverse cutaneous reactions were associated with the herbal treatment. The investigators found the combination of Belides, emblica, and licorice to be a safe and effective option for treating melasma (An. Bras. Dermatol. 2010;85:613-20). Previously, Belides was shown to be nearly twice as active as arbutin and an effective skin-lightening agent in a pilot study with human volunteers (SOFW J. 2005;131:40-9; Lim, T.K. Edible Medicinal and Non-Medicinal Plants. Springer: Dordrecht, 2014, pp. 204-11).

 

 

Conclusion

The roots and flowers of B. perennis have been used for many years in traditional medicine to treat various conditions, including skin disorders. While modern scientific interest has been piqued, the current body of evidence is meager. Much more research is necessary to determine the potential role of topical B. perennis in the dermatologic armamentarium. But recent data and the history of traditional use suggest that such research is warranted.

Dr. Baumann is chief executive officer of the Baumann Cosmetic & Research Institute in Miami Beach. She founded the cosmetic dermatology center at the University of Miami in 1997. Dr. Baumann wrote the textbook "Cosmetic Dermatology: Principles and Practice" (McGraw-Hill, April 2002), and a book for consumers, "The Skin Type Solution" (Bantam, 2006). She has contributed to the Cosmeceutical Critique column in Skin & Allergy News since January 2001 and joined the editorial advisory board in 2004. Dr. Baumann has received funding for clinical grants from Allergan, Aveeno, Avon Products, Galderma, Mary Kay, Medicis Pharmaceuticals, Neutrogena, Philosophy, Stiefel, Topix Pharmaceuticals, and Unilever.

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Approach to newborns exposed to HSV at the time of delivery

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Recently the American Academy of Pediatrics issued recommendations that address management of asymptomatic newborns whose mothers have active herpes simplex virus (HSV) lesions noted at the time of delivery. Implementing these recommendations requires proactive coordination between the director of the laboratory and the obstetrical and pediatric providers to ensure success (Pediatrics 2013;131:e635-46).

Approximately 1,500 infants are diagnosed and treated for neonatal HSV infection each year in the United States. Most pediatricians are knowledgeable about the three forms of neonatal HSV infection and the role of prompt diagnosis and utilization of acyclovir. Even so, the outcomes of this disease may be devastating. Skin–eye–mucous membrane disease has the best prognosis (98% neurologically normal), as finding the culprit lesion generally ensures timely diagnosis and treatment. With central nervous system infection or disseminated disease, a skin lesion is not noted in 25%-40% of cases. So the diagnosis is sometimes delayed or missed initially because the initial presentations (seizures in CNS infection; sepsis picture or liver failure in disseminated disease) may sidetrack the provider into considering other working diagnoses, such as bacterial sepsis or metabolic disease. Neurologic sequelae occur in 25% of those with disseminated infection, but in upward of 70% in those with CNS disease.

Ideally, both the obstetrician and the pediatric provider play a role in ensuring appropriate care for the baby whose mother has active HSV lesions at time of delivery. Appropriate care includes preemptive treatment for neonatal HSV infection, which has the potential to improve outcomes and so should be a high priority for all providers.

The new guidance is evidence based and predicated on the availability of HSV typing of the HSV from the maternal lesion and type-specific serology. It allows the provider to define the newborn risk of acquiring HSV infection more explicitly and utilize preemptive evaluation/therapy. Providers should ensure that their hospital laboratory can perform such testing with reasonable turnaround time for results.

Obstetrical role and implications of testing

The obstetric provider should swab the maternal lesion for HSV polymerase chain reaction (PCR) assay/culture and typing (HSV-1 or HSV-2). These data can be utilized with maternal history and serologic results to calculate the neonatal risk for infection.

Calculation of relative neonatal risk

First episode, primary infection. Defined as the first maternal HSV episode with type-specific serology being negative, this makes the risk of neonatal infection approximately 50%. If maternal history of prior disease is negative AND either the maternal lesion test results or serology results are unavailable, follow the plan of care for first episode primary infection.

First episode, nonprimary infection. Defined as the first maternal episode but antibody to detected HSV type is not present (e.g., HSV-2 confirmed from lesion, with type 1 but NOT type 2 maternal antibody present; OR HSV-1 confirmed, with type 2 but NOT type 1 maternal antibody present), the risk of neonatal infection is approximately 25%.

Recurrent. If the mother has a history of genital herpes and the mother’s type-specific antibody is the same as the type detected in the lesions, the risk for neonatal infection is lower and approximately 2%.

Pediatrician’s role and plan of care

The first order of business is to identify neonates who demonstrate signs or symptoms suggestive of HSV infection at birth or in the perinatal period (whether or not any lesions were noted at time of delivery). In this case, all infants should undergo full evaluation for both viral and bacterial causes and should have prompt initiation of preemptive antiviral and antibacterial therapy. The evaluation of an ill-appearing infant at birth should include CBC; liver function studies; blood, urine, and cerebrospinal fluid examination with bacterial cultures of blood, urine, and cerebrospinal fluid, plus blood and cerebrospinal fluid HSV PCR. Also, HSV surface (conjunctivae, nasopharynx, and rectum) and lesion cultures are needed. Infectious disease consultation is recommended if HSV infection is confirmed. Acyclovir should continue for 14 days for skin–eye–mucous membrane disease or 21 days for CNS or disseminated infection. Further evaluation toward the end of therapy can determine if a longer course of therapy should be considered.

The recent guideline addresses care for those infants who are born to mothers with active HSV lesions noted at time of delivery, and should be initiated only if the infant is asymptomatic at birth.

In this situation, for babies whose mothers have primary infection (risk 50% for neonatal infection) or first episode, nonprimary infection (risk 25% for neonatal infection):

• Approximately 24 hours after the infant’s birth, obtain blood HSV DNA PCR and HSV surface cultures of conjunctivae, nasopharynx, and rectum as well as from the scalp electrode site if there was one.

 

 

• Cerebrospinal fluid examination with HSV DNA PCR testing should be obtained.

• Acyclovir (20 mg/kg per dose every 8 hours IV) should be initiated. Preemptive therapy (acyclovir 20 mg/kg per dose every 8 hours IV) should be continued for 10 days and until all studies are negative.

For babies whose mothers have recurrent infection:

• Cerebrospinal fluid examination may be deferred.

• But the rest of the workup should be completed and IV acyclovir initiated.

• IV acyclovir can be stopped at the time that studies are negative (usually at 48 hours, assuming negative results of blood PCR and preliminary negative surface cultures), with close follow-up of the infant.

Use of this guideline can improve care of infants only when the laboratory and the obstetrical and pediatric providers have established a good working relationship. This ensures the availability of necessary HSV studies, complete implementation, and proper interpretation of testing to guide the newborn’s care.

Dr. Jackson is chief of pediatric infectious diseases at Children’s Mercy Hospital, Kansas City, Mo., and professor of pediatrics at the University of Missouri–Kansas City. Dr. Jackson was a member of the AAP Committee on Infectious Diseases who wrote the AAP clinical report entitled "Guidance on Management of Asymptomatic Neonates Born to Women With Active Genital Herpes Lesions," but said she had no other conflicts of interest to disclose. E-mail her at [email protected].

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Recently the American Academy of Pediatrics issued recommendations that address management of asymptomatic newborns whose mothers have active herpes simplex virus (HSV) lesions noted at the time of delivery. Implementing these recommendations requires proactive coordination between the director of the laboratory and the obstetrical and pediatric providers to ensure success (Pediatrics 2013;131:e635-46).

Approximately 1,500 infants are diagnosed and treated for neonatal HSV infection each year in the United States. Most pediatricians are knowledgeable about the three forms of neonatal HSV infection and the role of prompt diagnosis and utilization of acyclovir. Even so, the outcomes of this disease may be devastating. Skin–eye–mucous membrane disease has the best prognosis (98% neurologically normal), as finding the culprit lesion generally ensures timely diagnosis and treatment. With central nervous system infection or disseminated disease, a skin lesion is not noted in 25%-40% of cases. So the diagnosis is sometimes delayed or missed initially because the initial presentations (seizures in CNS infection; sepsis picture or liver failure in disseminated disease) may sidetrack the provider into considering other working diagnoses, such as bacterial sepsis or metabolic disease. Neurologic sequelae occur in 25% of those with disseminated infection, but in upward of 70% in those with CNS disease.

Ideally, both the obstetrician and the pediatric provider play a role in ensuring appropriate care for the baby whose mother has active HSV lesions at time of delivery. Appropriate care includes preemptive treatment for neonatal HSV infection, which has the potential to improve outcomes and so should be a high priority for all providers.

The new guidance is evidence based and predicated on the availability of HSV typing of the HSV from the maternal lesion and type-specific serology. It allows the provider to define the newborn risk of acquiring HSV infection more explicitly and utilize preemptive evaluation/therapy. Providers should ensure that their hospital laboratory can perform such testing with reasonable turnaround time for results.

Obstetrical role and implications of testing

The obstetric provider should swab the maternal lesion for HSV polymerase chain reaction (PCR) assay/culture and typing (HSV-1 or HSV-2). These data can be utilized with maternal history and serologic results to calculate the neonatal risk for infection.

Calculation of relative neonatal risk

First episode, primary infection. Defined as the first maternal HSV episode with type-specific serology being negative, this makes the risk of neonatal infection approximately 50%. If maternal history of prior disease is negative AND either the maternal lesion test results or serology results are unavailable, follow the plan of care for first episode primary infection.

First episode, nonprimary infection. Defined as the first maternal episode but antibody to detected HSV type is not present (e.g., HSV-2 confirmed from lesion, with type 1 but NOT type 2 maternal antibody present; OR HSV-1 confirmed, with type 2 but NOT type 1 maternal antibody present), the risk of neonatal infection is approximately 25%.

Recurrent. If the mother has a history of genital herpes and the mother’s type-specific antibody is the same as the type detected in the lesions, the risk for neonatal infection is lower and approximately 2%.

Pediatrician’s role and plan of care

The first order of business is to identify neonates who demonstrate signs or symptoms suggestive of HSV infection at birth or in the perinatal period (whether or not any lesions were noted at time of delivery). In this case, all infants should undergo full evaluation for both viral and bacterial causes and should have prompt initiation of preemptive antiviral and antibacterial therapy. The evaluation of an ill-appearing infant at birth should include CBC; liver function studies; blood, urine, and cerebrospinal fluid examination with bacterial cultures of blood, urine, and cerebrospinal fluid, plus blood and cerebrospinal fluid HSV PCR. Also, HSV surface (conjunctivae, nasopharynx, and rectum) and lesion cultures are needed. Infectious disease consultation is recommended if HSV infection is confirmed. Acyclovir should continue for 14 days for skin–eye–mucous membrane disease or 21 days for CNS or disseminated infection. Further evaluation toward the end of therapy can determine if a longer course of therapy should be considered.

The recent guideline addresses care for those infants who are born to mothers with active HSV lesions noted at time of delivery, and should be initiated only if the infant is asymptomatic at birth.

In this situation, for babies whose mothers have primary infection (risk 50% for neonatal infection) or first episode, nonprimary infection (risk 25% for neonatal infection):

• Approximately 24 hours after the infant’s birth, obtain blood HSV DNA PCR and HSV surface cultures of conjunctivae, nasopharynx, and rectum as well as from the scalp electrode site if there was one.

 

 

• Cerebrospinal fluid examination with HSV DNA PCR testing should be obtained.

• Acyclovir (20 mg/kg per dose every 8 hours IV) should be initiated. Preemptive therapy (acyclovir 20 mg/kg per dose every 8 hours IV) should be continued for 10 days and until all studies are negative.

For babies whose mothers have recurrent infection:

• Cerebrospinal fluid examination may be deferred.

• But the rest of the workup should be completed and IV acyclovir initiated.

• IV acyclovir can be stopped at the time that studies are negative (usually at 48 hours, assuming negative results of blood PCR and preliminary negative surface cultures), with close follow-up of the infant.

Use of this guideline can improve care of infants only when the laboratory and the obstetrical and pediatric providers have established a good working relationship. This ensures the availability of necessary HSV studies, complete implementation, and proper interpretation of testing to guide the newborn’s care.

Dr. Jackson is chief of pediatric infectious diseases at Children’s Mercy Hospital, Kansas City, Mo., and professor of pediatrics at the University of Missouri–Kansas City. Dr. Jackson was a member of the AAP Committee on Infectious Diseases who wrote the AAP clinical report entitled "Guidance on Management of Asymptomatic Neonates Born to Women With Active Genital Herpes Lesions," but said she had no other conflicts of interest to disclose. E-mail her at [email protected].

Recently the American Academy of Pediatrics issued recommendations that address management of asymptomatic newborns whose mothers have active herpes simplex virus (HSV) lesions noted at the time of delivery. Implementing these recommendations requires proactive coordination between the director of the laboratory and the obstetrical and pediatric providers to ensure success (Pediatrics 2013;131:e635-46).

Approximately 1,500 infants are diagnosed and treated for neonatal HSV infection each year in the United States. Most pediatricians are knowledgeable about the three forms of neonatal HSV infection and the role of prompt diagnosis and utilization of acyclovir. Even so, the outcomes of this disease may be devastating. Skin–eye–mucous membrane disease has the best prognosis (98% neurologically normal), as finding the culprit lesion generally ensures timely diagnosis and treatment. With central nervous system infection or disseminated disease, a skin lesion is not noted in 25%-40% of cases. So the diagnosis is sometimes delayed or missed initially because the initial presentations (seizures in CNS infection; sepsis picture or liver failure in disseminated disease) may sidetrack the provider into considering other working diagnoses, such as bacterial sepsis or metabolic disease. Neurologic sequelae occur in 25% of those with disseminated infection, but in upward of 70% in those with CNS disease.

Ideally, both the obstetrician and the pediatric provider play a role in ensuring appropriate care for the baby whose mother has active HSV lesions at time of delivery. Appropriate care includes preemptive treatment for neonatal HSV infection, which has the potential to improve outcomes and so should be a high priority for all providers.

The new guidance is evidence based and predicated on the availability of HSV typing of the HSV from the maternal lesion and type-specific serology. It allows the provider to define the newborn risk of acquiring HSV infection more explicitly and utilize preemptive evaluation/therapy. Providers should ensure that their hospital laboratory can perform such testing with reasonable turnaround time for results.

Obstetrical role and implications of testing

The obstetric provider should swab the maternal lesion for HSV polymerase chain reaction (PCR) assay/culture and typing (HSV-1 or HSV-2). These data can be utilized with maternal history and serologic results to calculate the neonatal risk for infection.

Calculation of relative neonatal risk

First episode, primary infection. Defined as the first maternal HSV episode with type-specific serology being negative, this makes the risk of neonatal infection approximately 50%. If maternal history of prior disease is negative AND either the maternal lesion test results or serology results are unavailable, follow the plan of care for first episode primary infection.

First episode, nonprimary infection. Defined as the first maternal episode but antibody to detected HSV type is not present (e.g., HSV-2 confirmed from lesion, with type 1 but NOT type 2 maternal antibody present; OR HSV-1 confirmed, with type 2 but NOT type 1 maternal antibody present), the risk of neonatal infection is approximately 25%.

Recurrent. If the mother has a history of genital herpes and the mother’s type-specific antibody is the same as the type detected in the lesions, the risk for neonatal infection is lower and approximately 2%.

Pediatrician’s role and plan of care

The first order of business is to identify neonates who demonstrate signs or symptoms suggestive of HSV infection at birth or in the perinatal period (whether or not any lesions were noted at time of delivery). In this case, all infants should undergo full evaluation for both viral and bacterial causes and should have prompt initiation of preemptive antiviral and antibacterial therapy. The evaluation of an ill-appearing infant at birth should include CBC; liver function studies; blood, urine, and cerebrospinal fluid examination with bacterial cultures of blood, urine, and cerebrospinal fluid, plus blood and cerebrospinal fluid HSV PCR. Also, HSV surface (conjunctivae, nasopharynx, and rectum) and lesion cultures are needed. Infectious disease consultation is recommended if HSV infection is confirmed. Acyclovir should continue for 14 days for skin–eye–mucous membrane disease or 21 days for CNS or disseminated infection. Further evaluation toward the end of therapy can determine if a longer course of therapy should be considered.

The recent guideline addresses care for those infants who are born to mothers with active HSV lesions noted at time of delivery, and should be initiated only if the infant is asymptomatic at birth.

In this situation, for babies whose mothers have primary infection (risk 50% for neonatal infection) or first episode, nonprimary infection (risk 25% for neonatal infection):

• Approximately 24 hours after the infant’s birth, obtain blood HSV DNA PCR and HSV surface cultures of conjunctivae, nasopharynx, and rectum as well as from the scalp electrode site if there was one.

 

 

• Cerebrospinal fluid examination with HSV DNA PCR testing should be obtained.

• Acyclovir (20 mg/kg per dose every 8 hours IV) should be initiated. Preemptive therapy (acyclovir 20 mg/kg per dose every 8 hours IV) should be continued for 10 days and until all studies are negative.

For babies whose mothers have recurrent infection:

• Cerebrospinal fluid examination may be deferred.

• But the rest of the workup should be completed and IV acyclovir initiated.

• IV acyclovir can be stopped at the time that studies are negative (usually at 48 hours, assuming negative results of blood PCR and preliminary negative surface cultures), with close follow-up of the infant.

Use of this guideline can improve care of infants only when the laboratory and the obstetrical and pediatric providers have established a good working relationship. This ensures the availability of necessary HSV studies, complete implementation, and proper interpretation of testing to guide the newborn’s care.

Dr. Jackson is chief of pediatric infectious diseases at Children’s Mercy Hospital, Kansas City, Mo., and professor of pediatrics at the University of Missouri–Kansas City. Dr. Jackson was a member of the AAP Committee on Infectious Diseases who wrote the AAP clinical report entitled "Guidance on Management of Asymptomatic Neonates Born to Women With Active Genital Herpes Lesions," but said she had no other conflicts of interest to disclose. E-mail her at [email protected].

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Growing EHR Pains

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It has been 2 months since we implemented an electronic health record. I’ve made peace with it, but it is oh so far from perfect. Around the office, tempers are flared and people are grumpy. There are threats to quit by staff and doctors alike. Chaotic accurately describes what the first few weeks were like.

For a week, I had a greatly thinned schedule, but was pretty much back up to my usual 15-minute follow-up schedule by week 3. This meant, frankly, that if I did not want my patients to be waiting for hours beyond their appointment time, shortcuts had to be made. And 2 months in, the trend continues. I am definitely not able to dutifully fill out each and every blank that meaningful use requires me to fill out. There is just not enough time to document every follow-up patient’s family history and surgical history all over again. If you thought pointing-and-clicking were going to make life much easier for you, think again.

The issue is that the electronic record, rather than being a blank space, is essentially pages and pages of blanks to be filled out. So instead of freely typing as the patient jumps from, say, the history of their present illness to their family history to their systems review back to their present illness – because as we all know, our patients do not tell their stories in a nice linear fashion – I find myself having to interrupt the patient as I find the right blank on the right page.

Another sore point for me, and of course this issue predates the EHR, is that I don’t like having to reduce my patients to codes. I understand that codes are useful, but they can also be limiting and, frankly, idiotic. For example, Medicare in Rhode Island will no longer reimburse for zoledronic acid for patients coded as 733.00 (Osteoporosis NOS), but will cover if a patient is coded as 733.01 (postmenopausal/senile osteoporosis). I would like to know who came up with that rule and how they came up with it.

Codes also fall short of really capturing what a patient looks like. One lupus patient can look quite different from the next. Some of my patients are extremely sick and have complicated histories that have taken many months to piece together, and those four digits just do not capture that complexity and absolutely do not do justice to the patient. Patients do not fit neatly into boxes, so why must we be forced to make them fit?

It is not all bad. There are definitely a number of things that I appreciate about having an EHR.

I like being able to access patient records from home. It makes call a lot easier when you have the ability to look up a patient, know what meds they’re on, and document what you did for them over the weekend.

I like being able to hand the patient a document at the end of the visit outlining what we talked about. Although composing this definitely slows me down, it is helpful for some of the more forgetful patients in our panel who cannot be expected to remember their instructions for tapering their prednisone or that methotrexate is taken weekly, not daily.

I like that our system has a homunculus and will automatically calculate the Clinical Disease Activity Index for me and track down the patient’s progress. The system is too new for me to use this functionality, but I look forward to trying it out.

I like being able to electronically prescribe meds. The med list can get cluttered with old medications that the patient is not taking anymore (how often do patients change NSAIDs or go from gabapentin to cyclobenzaprine to amitriptyline?), and it can get quite confusing, but I’m sure in the long run it will make life much easier. When I fill out the blasted prior authorization forms, I will now be able to check on a single screen what generic drugs the patient has failed.

I must admit that the forthcoming Medicare penalty for not having an EHR was a big motivator for us to get on board. In the end, though, it shouldn’t be about avoiding penalties. It should be about providing better-quality care. And once most doctors are on board and Medicare has access to measurable data, I fervently hope that the data shows us that all of this pain was worth it.

Dr. Chan practices rheumatology in Pawtucket, R.I.

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It has been 2 months since we implemented an electronic health record. I’ve made peace with it, but it is oh so far from perfect. Around the office, tempers are flared and people are grumpy. There are threats to quit by staff and doctors alike. Chaotic accurately describes what the first few weeks were like.

For a week, I had a greatly thinned schedule, but was pretty much back up to my usual 15-minute follow-up schedule by week 3. This meant, frankly, that if I did not want my patients to be waiting for hours beyond their appointment time, shortcuts had to be made. And 2 months in, the trend continues. I am definitely not able to dutifully fill out each and every blank that meaningful use requires me to fill out. There is just not enough time to document every follow-up patient’s family history and surgical history all over again. If you thought pointing-and-clicking were going to make life much easier for you, think again.

The issue is that the electronic record, rather than being a blank space, is essentially pages and pages of blanks to be filled out. So instead of freely typing as the patient jumps from, say, the history of their present illness to their family history to their systems review back to their present illness – because as we all know, our patients do not tell their stories in a nice linear fashion – I find myself having to interrupt the patient as I find the right blank on the right page.

Another sore point for me, and of course this issue predates the EHR, is that I don’t like having to reduce my patients to codes. I understand that codes are useful, but they can also be limiting and, frankly, idiotic. For example, Medicare in Rhode Island will no longer reimburse for zoledronic acid for patients coded as 733.00 (Osteoporosis NOS), but will cover if a patient is coded as 733.01 (postmenopausal/senile osteoporosis). I would like to know who came up with that rule and how they came up with it.

Codes also fall short of really capturing what a patient looks like. One lupus patient can look quite different from the next. Some of my patients are extremely sick and have complicated histories that have taken many months to piece together, and those four digits just do not capture that complexity and absolutely do not do justice to the patient. Patients do not fit neatly into boxes, so why must we be forced to make them fit?

It is not all bad. There are definitely a number of things that I appreciate about having an EHR.

I like being able to access patient records from home. It makes call a lot easier when you have the ability to look up a patient, know what meds they’re on, and document what you did for them over the weekend.

I like being able to hand the patient a document at the end of the visit outlining what we talked about. Although composing this definitely slows me down, it is helpful for some of the more forgetful patients in our panel who cannot be expected to remember their instructions for tapering their prednisone or that methotrexate is taken weekly, not daily.

I like that our system has a homunculus and will automatically calculate the Clinical Disease Activity Index for me and track down the patient’s progress. The system is too new for me to use this functionality, but I look forward to trying it out.

I like being able to electronically prescribe meds. The med list can get cluttered with old medications that the patient is not taking anymore (how often do patients change NSAIDs or go from gabapentin to cyclobenzaprine to amitriptyline?), and it can get quite confusing, but I’m sure in the long run it will make life much easier. When I fill out the blasted prior authorization forms, I will now be able to check on a single screen what generic drugs the patient has failed.

I must admit that the forthcoming Medicare penalty for not having an EHR was a big motivator for us to get on board. In the end, though, it shouldn’t be about avoiding penalties. It should be about providing better-quality care. And once most doctors are on board and Medicare has access to measurable data, I fervently hope that the data shows us that all of this pain was worth it.

Dr. Chan practices rheumatology in Pawtucket, R.I.

It has been 2 months since we implemented an electronic health record. I’ve made peace with it, but it is oh so far from perfect. Around the office, tempers are flared and people are grumpy. There are threats to quit by staff and doctors alike. Chaotic accurately describes what the first few weeks were like.

For a week, I had a greatly thinned schedule, but was pretty much back up to my usual 15-minute follow-up schedule by week 3. This meant, frankly, that if I did not want my patients to be waiting for hours beyond their appointment time, shortcuts had to be made. And 2 months in, the trend continues. I am definitely not able to dutifully fill out each and every blank that meaningful use requires me to fill out. There is just not enough time to document every follow-up patient’s family history and surgical history all over again. If you thought pointing-and-clicking were going to make life much easier for you, think again.

The issue is that the electronic record, rather than being a blank space, is essentially pages and pages of blanks to be filled out. So instead of freely typing as the patient jumps from, say, the history of their present illness to their family history to their systems review back to their present illness – because as we all know, our patients do not tell their stories in a nice linear fashion – I find myself having to interrupt the patient as I find the right blank on the right page.

Another sore point for me, and of course this issue predates the EHR, is that I don’t like having to reduce my patients to codes. I understand that codes are useful, but they can also be limiting and, frankly, idiotic. For example, Medicare in Rhode Island will no longer reimburse for zoledronic acid for patients coded as 733.00 (Osteoporosis NOS), but will cover if a patient is coded as 733.01 (postmenopausal/senile osteoporosis). I would like to know who came up with that rule and how they came up with it.

Codes also fall short of really capturing what a patient looks like. One lupus patient can look quite different from the next. Some of my patients are extremely sick and have complicated histories that have taken many months to piece together, and those four digits just do not capture that complexity and absolutely do not do justice to the patient. Patients do not fit neatly into boxes, so why must we be forced to make them fit?

It is not all bad. There are definitely a number of things that I appreciate about having an EHR.

I like being able to access patient records from home. It makes call a lot easier when you have the ability to look up a patient, know what meds they’re on, and document what you did for them over the weekend.

I like being able to hand the patient a document at the end of the visit outlining what we talked about. Although composing this definitely slows me down, it is helpful for some of the more forgetful patients in our panel who cannot be expected to remember their instructions for tapering their prednisone or that methotrexate is taken weekly, not daily.

I like that our system has a homunculus and will automatically calculate the Clinical Disease Activity Index for me and track down the patient’s progress. The system is too new for me to use this functionality, but I look forward to trying it out.

I like being able to electronically prescribe meds. The med list can get cluttered with old medications that the patient is not taking anymore (how often do patients change NSAIDs or go from gabapentin to cyclobenzaprine to amitriptyline?), and it can get quite confusing, but I’m sure in the long run it will make life much easier. When I fill out the blasted prior authorization forms, I will now be able to check on a single screen what generic drugs the patient has failed.

I must admit that the forthcoming Medicare penalty for not having an EHR was a big motivator for us to get on board. In the end, though, it shouldn’t be about avoiding penalties. It should be about providing better-quality care. And once most doctors are on board and Medicare has access to measurable data, I fervently hope that the data shows us that all of this pain was worth it.

Dr. Chan practices rheumatology in Pawtucket, R.I.

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Talking with families about corporal punishment

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One of the issues that can push your button as a pediatrician is hearing from your nurse that the parent you are about to see hit the child in the waiting room. Sometimes, the parent even hits the child right in front of you during the visit!

Your first reaction may be to want to tell the parents not to spank. But how well does that advice work?

Parents tend to use the same methods of child rearing that were used for them when they were growing up. This is deeply ingrained and tends to be accepted as "natural" even when they do not rationally believe in it. This requires that any intervention about corporal punishment be a conversation, not an edict from you. They may nod their heads if you tell them not to spank, but shut out any future advice from you on this topic.

Dr. Barbara Howard

There are some real facts that can help you address the parents’ reasons for spanking. The first "fact" that pediatricians often pull out is that "hitting the child does not work." Wrong. Hitting a child works fast to stop an unwanted behavior – but it has side effects. If you deny this, you lose credibility. If you acknowledge this, you will have the ears of the parents. Then you can point out some related truths – the child will soon go back to the same behavior whether hit or not because that is what young children do. Avoiding repeat behavior requires adjusting the environment, removing the child, and often changing the mood of the interaction. It is a fact that painful punishments must be progressively increased to maintain effectiveness and make nonpainful interventions less effective. I sometimes muse, "What are the teachers going to do at school if only hitting can control his behavior?"

The next fact is that other consequences, notably time out, work just as well as spanking to reduce unwanted behaviors, but without the side effects. What are these side effects? There are immediate side effects of corporal punishment, even if no bruising or harm occurs, and also long-term side effects. The immediate side effects are to increase the child’s aggressiveness to peers, siblings, and often the parent, and to increase fear of the parent. Fear of the parent undermines the child’s wanting to do as the parent asks, makes the child avoid the parent – making him/her less available to all parenting, and interferes with the problem solving that the child needs to do when facing a stressful situation such as conflict with a sibling. Longer term fear of the parent makes a child sneaky and less likely to admit mistakes. That is certainly not what anyone wants, especially when the child becomes a teen.

It may be hard to believe, but 25% of infants 1-6 months and 50% of infants 6-12 months are spanked for discipline. The implication is that it is never too early to have a conversation about discipline – certainly by 12 months of age. This early teaching helps parents establish control and helps prevent the early use of corporal punishment. Help parents understand that infants cannot learn to avoid a behavior from being struck; they can only become confused and frightened of their parent. In fact, 0- to 23-month-old white (not black or Latino) children had worse behavior at 6 years if they were frequently spanked, even controlling for maternal warmth (Pediatrics 2004;113:1321-1330).

Hitting a child is especially dangerous for children under age 2 years due to their size and head/body proportions. At this stage, a hit by an adult is more likely to cause serious injury even when the adult thought they were under control and managing the amount of force used. It is sobering to know that one-third of child abuse occurs to children under 6 months of age. If evidence of abuse is seen, it is your obligation to report it immediately. But you have a lot more value in educating about effective and safe discipline early on to prevent this. The American Academy of Pediatrics recommends that parents be "assisted in the development of methods other than spanking for managing undesired behavior" and that means you!

But doesn’t a toddler need discipline to learn how to behave? We know that verbal correction without action actually increases noncompliance in toddlers. But in one study, two-thirds of children under age 6 years were hit in the last week, on average 3 times per week. This is because toddlers and preschoolers typically misbehave every 6-8 minutes! Some consequence is needed as a back-up to reasoning to decrease recurrence of misbehavior, but noncorporal consequences are equally effective. The more children ages 3-6 years are spanked, the greater their antisocial behavior 2 years later, controlled for baseline behavior. Even IQ is lower at age 4 years when there is more spanking.

 

 

Asking older children "What happens if you do something bad" is a regular part of my visits. Why? Because 60% of 10- to 12-year-olds are struck and have increased aggression and decreased self-esteem as a result. Don’t forget that 40% of 14-year-olds and 25% of 17-year-olds are still hit even though the result is that 8- to 17-year olds who are struck have increased delinquency, controlling for family violence, alcohol, and parenting competence.

Most parents do not want to hit their child. Actually, 85% of parents who believe in spanking say that it was the wrong thing to have done the last time they used it. Yet about 90% of parents hit their 3-year-olds. Why? Parents who hit say that they don’t know what else to do when their children act out. They may try not to spank, but end up spanking out of anger and frustration. And hitting not only stops behavior, but also relieves the anger parents feel in dealing with their child. Even though they may regret it afterward, it feels good to them at the time.

How can you approach this touchy subject with your patients? The first principle is to resist your impulse to correct the parent and instead say nothing – at least right away. Carry on your visit and observe the child’s behavior. Some misbehavior is likely to appear. Then comment on what you see about child – "He sure is busy!" Then ask, "How is that for you?", or "How bad does it get?" Be nonjudgmental. Instead praise acceptable techniques they already use well, such as distracting the child or removing temptation.

Because parenting is learned from our own experiences, it is important to explore how the parents were raised. You might start by asking, "How would your parents have handled that behavior when you were growing up?" then "What have you decided about how you want to discipline your children?" Often, you will find that they do not want to repeat history, but don’t know other ways. Now you have an opening to offer other effective techniques. You might even ask permission, for example, "Would you like to hear about some other things that can work?" The main strategies you can teach quickly include first paying attention to acceptable behavior, and also proper use of Time Out. For toddlers and preschoolers, I also teach parents to use "only one request then move" the child silently to do as told.

Your advice will be more effective when you individualize the plan to make small adjustments to their current parenting with which the family can agree and be successful. For example, if one parent is willing to try these alternatives but the other is not or is unsure I suggest an agreement for use of Time Out instead of hitting for 2-3 weeks by the willing parent and noninterference plus limits on physical punishment (spank on clothed buttocks only) by the other parent. What usually happens is that the "Time Out parent" has success in this time period, and the other parent sees this and adopts the same method. It is really important to schedule one or more follow up visits soon, at least by phone, to reinforce their success and problem solve any difficulties. Changing such an ingrained habit is difficult but worthwhile and deserves your support.

Advising to avoid corporal punishment can be even more difficult for some doctors and in some settings. You may have been raised with spanking yourself and see it as not harmful or even helpful to your own development. Remember, spanking only increases the chances of a poor outcome by a factor of four, so most people grow up fine! The parents’ or your religion may even advise the use of spanking. I like to translate "spare the rod" as meaning "draw a line in the sand with the rod" to set limits. You may be of a different culture than your patient in which their belief is that corporal punishment is the key to neighborhood survival and gaining the child’s respect. But a child who is hit is actually more likely to bring him/herself trouble through aggression or delinquency.

To be effective in counseling about corporal punishment, you need to be clear about your own ideas on the acceptability of hitting. You need to be rational and avoid strong emotions during the visit. Instead, show empathy to the difficulties of parenting and work to understand and address the parents’ justifications for spanking with the facts. If you have shown knowledge of behavior and development in the regular care you provide, you will be a credible source and influence on this important area.

 

 

Dr. Howard is assistant professor of pediatrics at Johns Hopkins University, Baltimore, and creator of CHADIS. She has no other relevant disclosures. Dr. Howard’s contribution to this publication was as a paid expert to Frontline Medical Communications. E-mail her at [email protected].

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One of the issues that can push your button as a pediatrician is hearing from your nurse that the parent you are about to see hit the child in the waiting room. Sometimes, the parent even hits the child right in front of you during the visit!

Your first reaction may be to want to tell the parents not to spank. But how well does that advice work?

Parents tend to use the same methods of child rearing that were used for them when they were growing up. This is deeply ingrained and tends to be accepted as "natural" even when they do not rationally believe in it. This requires that any intervention about corporal punishment be a conversation, not an edict from you. They may nod their heads if you tell them not to spank, but shut out any future advice from you on this topic.

Dr. Barbara Howard

There are some real facts that can help you address the parents’ reasons for spanking. The first "fact" that pediatricians often pull out is that "hitting the child does not work." Wrong. Hitting a child works fast to stop an unwanted behavior – but it has side effects. If you deny this, you lose credibility. If you acknowledge this, you will have the ears of the parents. Then you can point out some related truths – the child will soon go back to the same behavior whether hit or not because that is what young children do. Avoiding repeat behavior requires adjusting the environment, removing the child, and often changing the mood of the interaction. It is a fact that painful punishments must be progressively increased to maintain effectiveness and make nonpainful interventions less effective. I sometimes muse, "What are the teachers going to do at school if only hitting can control his behavior?"

The next fact is that other consequences, notably time out, work just as well as spanking to reduce unwanted behaviors, but without the side effects. What are these side effects? There are immediate side effects of corporal punishment, even if no bruising or harm occurs, and also long-term side effects. The immediate side effects are to increase the child’s aggressiveness to peers, siblings, and often the parent, and to increase fear of the parent. Fear of the parent undermines the child’s wanting to do as the parent asks, makes the child avoid the parent – making him/her less available to all parenting, and interferes with the problem solving that the child needs to do when facing a stressful situation such as conflict with a sibling. Longer term fear of the parent makes a child sneaky and less likely to admit mistakes. That is certainly not what anyone wants, especially when the child becomes a teen.

It may be hard to believe, but 25% of infants 1-6 months and 50% of infants 6-12 months are spanked for discipline. The implication is that it is never too early to have a conversation about discipline – certainly by 12 months of age. This early teaching helps parents establish control and helps prevent the early use of corporal punishment. Help parents understand that infants cannot learn to avoid a behavior from being struck; they can only become confused and frightened of their parent. In fact, 0- to 23-month-old white (not black or Latino) children had worse behavior at 6 years if they were frequently spanked, even controlling for maternal warmth (Pediatrics 2004;113:1321-1330).

Hitting a child is especially dangerous for children under age 2 years due to their size and head/body proportions. At this stage, a hit by an adult is more likely to cause serious injury even when the adult thought they were under control and managing the amount of force used. It is sobering to know that one-third of child abuse occurs to children under 6 months of age. If evidence of abuse is seen, it is your obligation to report it immediately. But you have a lot more value in educating about effective and safe discipline early on to prevent this. The American Academy of Pediatrics recommends that parents be "assisted in the development of methods other than spanking for managing undesired behavior" and that means you!

But doesn’t a toddler need discipline to learn how to behave? We know that verbal correction without action actually increases noncompliance in toddlers. But in one study, two-thirds of children under age 6 years were hit in the last week, on average 3 times per week. This is because toddlers and preschoolers typically misbehave every 6-8 minutes! Some consequence is needed as a back-up to reasoning to decrease recurrence of misbehavior, but noncorporal consequences are equally effective. The more children ages 3-6 years are spanked, the greater their antisocial behavior 2 years later, controlled for baseline behavior. Even IQ is lower at age 4 years when there is more spanking.

 

 

Asking older children "What happens if you do something bad" is a regular part of my visits. Why? Because 60% of 10- to 12-year-olds are struck and have increased aggression and decreased self-esteem as a result. Don’t forget that 40% of 14-year-olds and 25% of 17-year-olds are still hit even though the result is that 8- to 17-year olds who are struck have increased delinquency, controlling for family violence, alcohol, and parenting competence.

Most parents do not want to hit their child. Actually, 85% of parents who believe in spanking say that it was the wrong thing to have done the last time they used it. Yet about 90% of parents hit their 3-year-olds. Why? Parents who hit say that they don’t know what else to do when their children act out. They may try not to spank, but end up spanking out of anger and frustration. And hitting not only stops behavior, but also relieves the anger parents feel in dealing with their child. Even though they may regret it afterward, it feels good to them at the time.

How can you approach this touchy subject with your patients? The first principle is to resist your impulse to correct the parent and instead say nothing – at least right away. Carry on your visit and observe the child’s behavior. Some misbehavior is likely to appear. Then comment on what you see about child – "He sure is busy!" Then ask, "How is that for you?", or "How bad does it get?" Be nonjudgmental. Instead praise acceptable techniques they already use well, such as distracting the child or removing temptation.

Because parenting is learned from our own experiences, it is important to explore how the parents were raised. You might start by asking, "How would your parents have handled that behavior when you were growing up?" then "What have you decided about how you want to discipline your children?" Often, you will find that they do not want to repeat history, but don’t know other ways. Now you have an opening to offer other effective techniques. You might even ask permission, for example, "Would you like to hear about some other things that can work?" The main strategies you can teach quickly include first paying attention to acceptable behavior, and also proper use of Time Out. For toddlers and preschoolers, I also teach parents to use "only one request then move" the child silently to do as told.

Your advice will be more effective when you individualize the plan to make small adjustments to their current parenting with which the family can agree and be successful. For example, if one parent is willing to try these alternatives but the other is not or is unsure I suggest an agreement for use of Time Out instead of hitting for 2-3 weeks by the willing parent and noninterference plus limits on physical punishment (spank on clothed buttocks only) by the other parent. What usually happens is that the "Time Out parent" has success in this time period, and the other parent sees this and adopts the same method. It is really important to schedule one or more follow up visits soon, at least by phone, to reinforce their success and problem solve any difficulties. Changing such an ingrained habit is difficult but worthwhile and deserves your support.

Advising to avoid corporal punishment can be even more difficult for some doctors and in some settings. You may have been raised with spanking yourself and see it as not harmful or even helpful to your own development. Remember, spanking only increases the chances of a poor outcome by a factor of four, so most people grow up fine! The parents’ or your religion may even advise the use of spanking. I like to translate "spare the rod" as meaning "draw a line in the sand with the rod" to set limits. You may be of a different culture than your patient in which their belief is that corporal punishment is the key to neighborhood survival and gaining the child’s respect. But a child who is hit is actually more likely to bring him/herself trouble through aggression or delinquency.

To be effective in counseling about corporal punishment, you need to be clear about your own ideas on the acceptability of hitting. You need to be rational and avoid strong emotions during the visit. Instead, show empathy to the difficulties of parenting and work to understand and address the parents’ justifications for spanking with the facts. If you have shown knowledge of behavior and development in the regular care you provide, you will be a credible source and influence on this important area.

 

 

Dr. Howard is assistant professor of pediatrics at Johns Hopkins University, Baltimore, and creator of CHADIS. She has no other relevant disclosures. Dr. Howard’s contribution to this publication was as a paid expert to Frontline Medical Communications. E-mail her at [email protected].

One of the issues that can push your button as a pediatrician is hearing from your nurse that the parent you are about to see hit the child in the waiting room. Sometimes, the parent even hits the child right in front of you during the visit!

Your first reaction may be to want to tell the parents not to spank. But how well does that advice work?

Parents tend to use the same methods of child rearing that were used for them when they were growing up. This is deeply ingrained and tends to be accepted as "natural" even when they do not rationally believe in it. This requires that any intervention about corporal punishment be a conversation, not an edict from you. They may nod their heads if you tell them not to spank, but shut out any future advice from you on this topic.

Dr. Barbara Howard

There are some real facts that can help you address the parents’ reasons for spanking. The first "fact" that pediatricians often pull out is that "hitting the child does not work." Wrong. Hitting a child works fast to stop an unwanted behavior – but it has side effects. If you deny this, you lose credibility. If you acknowledge this, you will have the ears of the parents. Then you can point out some related truths – the child will soon go back to the same behavior whether hit or not because that is what young children do. Avoiding repeat behavior requires adjusting the environment, removing the child, and often changing the mood of the interaction. It is a fact that painful punishments must be progressively increased to maintain effectiveness and make nonpainful interventions less effective. I sometimes muse, "What are the teachers going to do at school if only hitting can control his behavior?"

The next fact is that other consequences, notably time out, work just as well as spanking to reduce unwanted behaviors, but without the side effects. What are these side effects? There are immediate side effects of corporal punishment, even if no bruising or harm occurs, and also long-term side effects. The immediate side effects are to increase the child’s aggressiveness to peers, siblings, and often the parent, and to increase fear of the parent. Fear of the parent undermines the child’s wanting to do as the parent asks, makes the child avoid the parent – making him/her less available to all parenting, and interferes with the problem solving that the child needs to do when facing a stressful situation such as conflict with a sibling. Longer term fear of the parent makes a child sneaky and less likely to admit mistakes. That is certainly not what anyone wants, especially when the child becomes a teen.

It may be hard to believe, but 25% of infants 1-6 months and 50% of infants 6-12 months are spanked for discipline. The implication is that it is never too early to have a conversation about discipline – certainly by 12 months of age. This early teaching helps parents establish control and helps prevent the early use of corporal punishment. Help parents understand that infants cannot learn to avoid a behavior from being struck; they can only become confused and frightened of their parent. In fact, 0- to 23-month-old white (not black or Latino) children had worse behavior at 6 years if they were frequently spanked, even controlling for maternal warmth (Pediatrics 2004;113:1321-1330).

Hitting a child is especially dangerous for children under age 2 years due to their size and head/body proportions. At this stage, a hit by an adult is more likely to cause serious injury even when the adult thought they were under control and managing the amount of force used. It is sobering to know that one-third of child abuse occurs to children under 6 months of age. If evidence of abuse is seen, it is your obligation to report it immediately. But you have a lot more value in educating about effective and safe discipline early on to prevent this. The American Academy of Pediatrics recommends that parents be "assisted in the development of methods other than spanking for managing undesired behavior" and that means you!

But doesn’t a toddler need discipline to learn how to behave? We know that verbal correction without action actually increases noncompliance in toddlers. But in one study, two-thirds of children under age 6 years were hit in the last week, on average 3 times per week. This is because toddlers and preschoolers typically misbehave every 6-8 minutes! Some consequence is needed as a back-up to reasoning to decrease recurrence of misbehavior, but noncorporal consequences are equally effective. The more children ages 3-6 years are spanked, the greater their antisocial behavior 2 years later, controlled for baseline behavior. Even IQ is lower at age 4 years when there is more spanking.

 

 

Asking older children "What happens if you do something bad" is a regular part of my visits. Why? Because 60% of 10- to 12-year-olds are struck and have increased aggression and decreased self-esteem as a result. Don’t forget that 40% of 14-year-olds and 25% of 17-year-olds are still hit even though the result is that 8- to 17-year olds who are struck have increased delinquency, controlling for family violence, alcohol, and parenting competence.

Most parents do not want to hit their child. Actually, 85% of parents who believe in spanking say that it was the wrong thing to have done the last time they used it. Yet about 90% of parents hit their 3-year-olds. Why? Parents who hit say that they don’t know what else to do when their children act out. They may try not to spank, but end up spanking out of anger and frustration. And hitting not only stops behavior, but also relieves the anger parents feel in dealing with their child. Even though they may regret it afterward, it feels good to them at the time.

How can you approach this touchy subject with your patients? The first principle is to resist your impulse to correct the parent and instead say nothing – at least right away. Carry on your visit and observe the child’s behavior. Some misbehavior is likely to appear. Then comment on what you see about child – "He sure is busy!" Then ask, "How is that for you?", or "How bad does it get?" Be nonjudgmental. Instead praise acceptable techniques they already use well, such as distracting the child or removing temptation.

Because parenting is learned from our own experiences, it is important to explore how the parents were raised. You might start by asking, "How would your parents have handled that behavior when you were growing up?" then "What have you decided about how you want to discipline your children?" Often, you will find that they do not want to repeat history, but don’t know other ways. Now you have an opening to offer other effective techniques. You might even ask permission, for example, "Would you like to hear about some other things that can work?" The main strategies you can teach quickly include first paying attention to acceptable behavior, and also proper use of Time Out. For toddlers and preschoolers, I also teach parents to use "only one request then move" the child silently to do as told.

Your advice will be more effective when you individualize the plan to make small adjustments to their current parenting with which the family can agree and be successful. For example, if one parent is willing to try these alternatives but the other is not or is unsure I suggest an agreement for use of Time Out instead of hitting for 2-3 weeks by the willing parent and noninterference plus limits on physical punishment (spank on clothed buttocks only) by the other parent. What usually happens is that the "Time Out parent" has success in this time period, and the other parent sees this and adopts the same method. It is really important to schedule one or more follow up visits soon, at least by phone, to reinforce their success and problem solve any difficulties. Changing such an ingrained habit is difficult but worthwhile and deserves your support.

Advising to avoid corporal punishment can be even more difficult for some doctors and in some settings. You may have been raised with spanking yourself and see it as not harmful or even helpful to your own development. Remember, spanking only increases the chances of a poor outcome by a factor of four, so most people grow up fine! The parents’ or your religion may even advise the use of spanking. I like to translate "spare the rod" as meaning "draw a line in the sand with the rod" to set limits. You may be of a different culture than your patient in which their belief is that corporal punishment is the key to neighborhood survival and gaining the child’s respect. But a child who is hit is actually more likely to bring him/herself trouble through aggression or delinquency.

To be effective in counseling about corporal punishment, you need to be clear about your own ideas on the acceptability of hitting. You need to be rational and avoid strong emotions during the visit. Instead, show empathy to the difficulties of parenting and work to understand and address the parents’ justifications for spanking with the facts. If you have shown knowledge of behavior and development in the regular care you provide, you will be a credible source and influence on this important area.

 

 

Dr. Howard is assistant professor of pediatrics at Johns Hopkins University, Baltimore, and creator of CHADIS. She has no other relevant disclosures. Dr. Howard’s contribution to this publication was as a paid expert to Frontline Medical Communications. E-mail her at [email protected].

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Atrial fibrillation: The unknown known

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For a problem that has been on the back burner for decades, the treatment of atrial fibrillation has suddenly become a "marquis" diagnosis.

Age and technology have led to an explosion of interest in this arcane cardiac problem. Advertisements for new anticoagulants and thrombin inhibitors for "A Fib" have become almost as common as those for male impotency. The aging of the world population certainly has been a major factor in its increased incidence. New technology and pharmacology has driven the increase in clinical interest and has advanced our knowledge about the disease. Epidemiology data have provided important information about the natural history of paroxysmal atrial fibrillation (AF), and its relationship to chronic AF and its adverse effects on long-term mortality.

The importance of anticoagulant therapy for the prevention of systemic emboli and stroke has been the mainstay of therapy for almost 50 years. Although we have struggled with a variety of antiarrhythmic drugs, their shortcomings have been more than apparent. Most of us now use a rate-control strategy to control the tachycardia inherent in AF. The development of new factor Xa and direct thrombin inhibitor drugs have made the logistics of providing adequate thrombus prevention much simpler, if somewhat more expensive.

The elephant in the room is the increasing use of radiofrequency catheter ablation technology that has had some success in the prevention of AF arising from the tissue in the pulmonary vein–atrial interface. Numerous small studies have reported that this technology surpasses rhythm control with antiarrhythmic agents, a hurdle not too difficult to beat. The best results have been observed in patients with recurrent paroxysmal AF where maintenance of regular sinus rhythm has been the primary outcome measurement (JAMA 2014;311:692-700). Even here, recurrence after ablation has been common. The benefit of ablation therapy in patients with initial paroxysmal AF (N. Engl. J. Med. 2012;367:1587-95) or chronic persistent AF has been uncertain at best. As a result, the AHA/ACC/HRS (American Heart Association/American College of Cardiology/Heart Rhythm Society) guidelines have given a class I (evidence level A) recommendation for ablation therapy for symptomatic paroxysmal AF and class IIa (evidence level A) and IIb (evidence level B) for symptomatic recurrent paroxysmal and longstanding persistent AF when balanced against drug tolerability, respectively (J. Am. Coll. Cardiol. 2014 [doi:10.1016/j.jacc.2014.03.021]).

All of these clinical data are exciting and have led to enthusiasm for ablation technology despite the potential for nonfatal and rare fatal complication, based almost entirely on its ability to improve upon the dismal benefits of antiarrhythmic rhythm control. Even as we consider the benefit of ablation therapy, new techniques are being developed. The lack of mortality and morbidity data is a result of the short follow-up, usually limited to a year or two, and small sample size. This lack of long-term outcome data for ablation therapy should be of some concern to clinicians who have lived through the last few years. Many of my readers had not been born when we embarked on the ineffective and dangerous pharmacologic prevention of sudden death by pharmacologic suppression of ambient ventricular premature beats. Numerous surrogate measures of clinical benefit of a variety of therapeutic interventions have been disproven and disposed of in the subsequent years. The use of surrogate measures like the partial suppression of AF rather than morbidity and mortality outcomes to establish clinical benefit, have been largely discarded as a dead end.

The Catheter Ablation Versus Anti-arrhythmic Drug Therapy for Atrial Fibrillation Trial (CABANA), which is beginning to recruit more than 2,000 patients with new-onset or undertreated paroxysmal, persistent, or longstanding AF to be followed for over 4 years may answer the question of whether radiofrequency ablation therapy, rate control, or rhythm control provides the best clinical treatment of atrial fibrillation. The primary outcome will be the composite endpoint of total mortality, disabling stroke or serious bleeding, or cardiac arrest. An important secondary endpoint will be total mortality. Until its conclusion, we should proceed cautiously with expanding radiofrequency ablation therapy for the treatment of AF.

Dr. Goldstein, medical editor of Cardiology News, is professor of medicine at Wayne State University and division head emeritus of cardiovascular medicine at Henry Ford Hospital, both in Detroit. He is on data safety monitoring committees for the National Institutes of Health and several pharmaceutical companies.

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For a problem that has been on the back burner for decades, the treatment of atrial fibrillation has suddenly become a "marquis" diagnosis.

Age and technology have led to an explosion of interest in this arcane cardiac problem. Advertisements for new anticoagulants and thrombin inhibitors for "A Fib" have become almost as common as those for male impotency. The aging of the world population certainly has been a major factor in its increased incidence. New technology and pharmacology has driven the increase in clinical interest and has advanced our knowledge about the disease. Epidemiology data have provided important information about the natural history of paroxysmal atrial fibrillation (AF), and its relationship to chronic AF and its adverse effects on long-term mortality.

The importance of anticoagulant therapy for the prevention of systemic emboli and stroke has been the mainstay of therapy for almost 50 years. Although we have struggled with a variety of antiarrhythmic drugs, their shortcomings have been more than apparent. Most of us now use a rate-control strategy to control the tachycardia inherent in AF. The development of new factor Xa and direct thrombin inhibitor drugs have made the logistics of providing adequate thrombus prevention much simpler, if somewhat more expensive.

The elephant in the room is the increasing use of radiofrequency catheter ablation technology that has had some success in the prevention of AF arising from the tissue in the pulmonary vein–atrial interface. Numerous small studies have reported that this technology surpasses rhythm control with antiarrhythmic agents, a hurdle not too difficult to beat. The best results have been observed in patients with recurrent paroxysmal AF where maintenance of regular sinus rhythm has been the primary outcome measurement (JAMA 2014;311:692-700). Even here, recurrence after ablation has been common. The benefit of ablation therapy in patients with initial paroxysmal AF (N. Engl. J. Med. 2012;367:1587-95) or chronic persistent AF has been uncertain at best. As a result, the AHA/ACC/HRS (American Heart Association/American College of Cardiology/Heart Rhythm Society) guidelines have given a class I (evidence level A) recommendation for ablation therapy for symptomatic paroxysmal AF and class IIa (evidence level A) and IIb (evidence level B) for symptomatic recurrent paroxysmal and longstanding persistent AF when balanced against drug tolerability, respectively (J. Am. Coll. Cardiol. 2014 [doi:10.1016/j.jacc.2014.03.021]).

All of these clinical data are exciting and have led to enthusiasm for ablation technology despite the potential for nonfatal and rare fatal complication, based almost entirely on its ability to improve upon the dismal benefits of antiarrhythmic rhythm control. Even as we consider the benefit of ablation therapy, new techniques are being developed. The lack of mortality and morbidity data is a result of the short follow-up, usually limited to a year or two, and small sample size. This lack of long-term outcome data for ablation therapy should be of some concern to clinicians who have lived through the last few years. Many of my readers had not been born when we embarked on the ineffective and dangerous pharmacologic prevention of sudden death by pharmacologic suppression of ambient ventricular premature beats. Numerous surrogate measures of clinical benefit of a variety of therapeutic interventions have been disproven and disposed of in the subsequent years. The use of surrogate measures like the partial suppression of AF rather than morbidity and mortality outcomes to establish clinical benefit, have been largely discarded as a dead end.

The Catheter Ablation Versus Anti-arrhythmic Drug Therapy for Atrial Fibrillation Trial (CABANA), which is beginning to recruit more than 2,000 patients with new-onset or undertreated paroxysmal, persistent, or longstanding AF to be followed for over 4 years may answer the question of whether radiofrequency ablation therapy, rate control, or rhythm control provides the best clinical treatment of atrial fibrillation. The primary outcome will be the composite endpoint of total mortality, disabling stroke or serious bleeding, or cardiac arrest. An important secondary endpoint will be total mortality. Until its conclusion, we should proceed cautiously with expanding radiofrequency ablation therapy for the treatment of AF.

Dr. Goldstein, medical editor of Cardiology News, is professor of medicine at Wayne State University and division head emeritus of cardiovascular medicine at Henry Ford Hospital, both in Detroit. He is on data safety monitoring committees for the National Institutes of Health and several pharmaceutical companies.

For a problem that has been on the back burner for decades, the treatment of atrial fibrillation has suddenly become a "marquis" diagnosis.

Age and technology have led to an explosion of interest in this arcane cardiac problem. Advertisements for new anticoagulants and thrombin inhibitors for "A Fib" have become almost as common as those for male impotency. The aging of the world population certainly has been a major factor in its increased incidence. New technology and pharmacology has driven the increase in clinical interest and has advanced our knowledge about the disease. Epidemiology data have provided important information about the natural history of paroxysmal atrial fibrillation (AF), and its relationship to chronic AF and its adverse effects on long-term mortality.

The importance of anticoagulant therapy for the prevention of systemic emboli and stroke has been the mainstay of therapy for almost 50 years. Although we have struggled with a variety of antiarrhythmic drugs, their shortcomings have been more than apparent. Most of us now use a rate-control strategy to control the tachycardia inherent in AF. The development of new factor Xa and direct thrombin inhibitor drugs have made the logistics of providing adequate thrombus prevention much simpler, if somewhat more expensive.

The elephant in the room is the increasing use of radiofrequency catheter ablation technology that has had some success in the prevention of AF arising from the tissue in the pulmonary vein–atrial interface. Numerous small studies have reported that this technology surpasses rhythm control with antiarrhythmic agents, a hurdle not too difficult to beat. The best results have been observed in patients with recurrent paroxysmal AF where maintenance of regular sinus rhythm has been the primary outcome measurement (JAMA 2014;311:692-700). Even here, recurrence after ablation has been common. The benefit of ablation therapy in patients with initial paroxysmal AF (N. Engl. J. Med. 2012;367:1587-95) or chronic persistent AF has been uncertain at best. As a result, the AHA/ACC/HRS (American Heart Association/American College of Cardiology/Heart Rhythm Society) guidelines have given a class I (evidence level A) recommendation for ablation therapy for symptomatic paroxysmal AF and class IIa (evidence level A) and IIb (evidence level B) for symptomatic recurrent paroxysmal and longstanding persistent AF when balanced against drug tolerability, respectively (J. Am. Coll. Cardiol. 2014 [doi:10.1016/j.jacc.2014.03.021]).

All of these clinical data are exciting and have led to enthusiasm for ablation technology despite the potential for nonfatal and rare fatal complication, based almost entirely on its ability to improve upon the dismal benefits of antiarrhythmic rhythm control. Even as we consider the benefit of ablation therapy, new techniques are being developed. The lack of mortality and morbidity data is a result of the short follow-up, usually limited to a year or two, and small sample size. This lack of long-term outcome data for ablation therapy should be of some concern to clinicians who have lived through the last few years. Many of my readers had not been born when we embarked on the ineffective and dangerous pharmacologic prevention of sudden death by pharmacologic suppression of ambient ventricular premature beats. Numerous surrogate measures of clinical benefit of a variety of therapeutic interventions have been disproven and disposed of in the subsequent years. The use of surrogate measures like the partial suppression of AF rather than morbidity and mortality outcomes to establish clinical benefit, have been largely discarded as a dead end.

The Catheter Ablation Versus Anti-arrhythmic Drug Therapy for Atrial Fibrillation Trial (CABANA), which is beginning to recruit more than 2,000 patients with new-onset or undertreated paroxysmal, persistent, or longstanding AF to be followed for over 4 years may answer the question of whether radiofrequency ablation therapy, rate control, or rhythm control provides the best clinical treatment of atrial fibrillation. The primary outcome will be the composite endpoint of total mortality, disabling stroke or serious bleeding, or cardiac arrest. An important secondary endpoint will be total mortality. Until its conclusion, we should proceed cautiously with expanding radiofrequency ablation therapy for the treatment of AF.

Dr. Goldstein, medical editor of Cardiology News, is professor of medicine at Wayne State University and division head emeritus of cardiovascular medicine at Henry Ford Hospital, both in Detroit. He is on data safety monitoring committees for the National Institutes of Health and several pharmaceutical companies.

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Being in the political crossfire is nothing new to the VA. The largest health care organization in the U.S. has seen its share of firestorms. And that’s okay. Transparency is essential for maintaining the public trust.

The mission to care for veterans and their families is one that the overwhelming majority of the 280,000 VA employees take extremely seriously. The reports of excessive wait times for veterans seeking care are disturbing to everyone inside and outside the VA. We fully expect the new Secretary of Veterans Affairs will act quickly to ensure that all veterans receive the care they deserve in a timely fashion.

Nevertheless, we remain concerned that the current climate may erode the trust that VA health care providers (HCPs) have earned. The vast majority continue to deliver high-quality care to a particularly vulnerable population. According to the latest American Customer Satisfaction Index, veterans are satisfied with the quality of care they receive at VA facilities. The VA, in fact, gets higher marks for its service than most other government agencies.1

As President Obama insisted in a May press conference: “Every single day, there are people working in the VA who do outstanding work and put everything they’ve got into making sure that our veterans get the care, benefits, and services that they need.” Unfortunately, not all critics recognize that commitment.

They should. There is important work being done by VA HCPs. For more than 30 years, Federal Practitioner has showcased the dedication of the men and women who deliver health care across government agencies. The VA has been the source of many important innovations over the years, like recognizing the importance of nurse practitioners in health care delivery. The VA Computerized Patient Record System exemplifies how an electronic health record system can improve health care.

We talk to many at the VA who are committed to sharing best practices, difficult case studies, and innovative programs, which often exist only because of the dedication and commitment of passionate HCPs. For example, Dr. Dewleen Baker of the VA San Diego Healthcare System who wanted to understand the causes of posttraumatic stress disorder (PTSD) and traumatic brain injuries (TBIs) in the military and among veterans. Rather than waiting until veterans came in the door, Dr. Baker created a massive study in cooperation with the U.S. Marines and Navy so that subjects could have baseline evaluations before deployment and could be monitored throughout their lives. The results of the study may provide essential insight into PTSD and TBI and will benefit not only veterans, but all patients.

Veterans do, in fact, have unique concerns and deserve an agency focused on their care. Too many veterans, for example, return from their service with a desperate need for palliative care and prescriptions for opioids. Replacing pain with addiction, however, remains a significant concern. In response, the VA Pharmacy Benefit Management Service developed an opioid monitoring dashboard to improve prescribing practices and reduce the use of opioids. The dashboard allows the VA to both see patterns across the entire system and to make exceptions for individual veterans, ensuring that each veteran gets exactly the care he or she needs.

Every issue of Federal Practitioner is replete with similar examples of HCPs who provide the best care possible within the budget constraints set by Congress. Whether it’s the development of an e-consult program to speed access to diabetes specialists, a training program on how to disclose adverse events, or the development of a clinic for patients with chronic stable angina, VA HCPs are focused on meeting the demanding health care needs of veterans.2-4

Federal Practitioner will continue to highlight the great work that is being done across the federal health care system, even when it is not popular. The benefits of the medical research and health care innovations are shared by all Americans. They have earned our trust and respect. So, let us know what you think (email or Facebook), and please continue to share your experiences serving your patients. That’s why we’re here.

Author disclosures
The author reports no actual or potential conflicts of interest with regard to this article.

References

 1. American Customer Satisfaction Index. ACSI Benchmarks for U.S. Federal Government 2013. http://www.theacsi.org/acsi-benchmarks-for-u-s-federal-government-2013. Published January 28, 2014. Accessed May 28, 2014.

 2. Vasudevan MM, Hurr SD, Green MC, et al. The clinical impact of electronic consultation in diabetes care. Fed Pract. 2014;31(3):32-36.

 3. Dunn EJ, McKinney KM, Martin ME. Empathic disclosure of adverse events to patients. Fed Pract. 2014;31(5):18-21.

 4. Gillette MA, Frohnapple DJ, Knott A, Reeder D. Pharmacist-managed collaborative practice for chronic stable angina. Fed Pract. 2014;31(6):16-22.

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Being in the political crossfire is nothing new to the VA. The largest health care organization in the U.S. has seen its share of firestorms. And that’s okay. Transparency is essential for maintaining the public trust.

The mission to care for veterans and their families is one that the overwhelming majority of the 280,000 VA employees take extremely seriously. The reports of excessive wait times for veterans seeking care are disturbing to everyone inside and outside the VA. We fully expect the new Secretary of Veterans Affairs will act quickly to ensure that all veterans receive the care they deserve in a timely fashion.

Nevertheless, we remain concerned that the current climate may erode the trust that VA health care providers (HCPs) have earned. The vast majority continue to deliver high-quality care to a particularly vulnerable population. According to the latest American Customer Satisfaction Index, veterans are satisfied with the quality of care they receive at VA facilities. The VA, in fact, gets higher marks for its service than most other government agencies.1

As President Obama insisted in a May press conference: “Every single day, there are people working in the VA who do outstanding work and put everything they’ve got into making sure that our veterans get the care, benefits, and services that they need.” Unfortunately, not all critics recognize that commitment.

They should. There is important work being done by VA HCPs. For more than 30 years, Federal Practitioner has showcased the dedication of the men and women who deliver health care across government agencies. The VA has been the source of many important innovations over the years, like recognizing the importance of nurse practitioners in health care delivery. The VA Computerized Patient Record System exemplifies how an electronic health record system can improve health care.

We talk to many at the VA who are committed to sharing best practices, difficult case studies, and innovative programs, which often exist only because of the dedication and commitment of passionate HCPs. For example, Dr. Dewleen Baker of the VA San Diego Healthcare System who wanted to understand the causes of posttraumatic stress disorder (PTSD) and traumatic brain injuries (TBIs) in the military and among veterans. Rather than waiting until veterans came in the door, Dr. Baker created a massive study in cooperation with the U.S. Marines and Navy so that subjects could have baseline evaluations before deployment and could be monitored throughout their lives. The results of the study may provide essential insight into PTSD and TBI and will benefit not only veterans, but all patients.

Veterans do, in fact, have unique concerns and deserve an agency focused on their care. Too many veterans, for example, return from their service with a desperate need for palliative care and prescriptions for opioids. Replacing pain with addiction, however, remains a significant concern. In response, the VA Pharmacy Benefit Management Service developed an opioid monitoring dashboard to improve prescribing practices and reduce the use of opioids. The dashboard allows the VA to both see patterns across the entire system and to make exceptions for individual veterans, ensuring that each veteran gets exactly the care he or she needs.

Every issue of Federal Practitioner is replete with similar examples of HCPs who provide the best care possible within the budget constraints set by Congress. Whether it’s the development of an e-consult program to speed access to diabetes specialists, a training program on how to disclose adverse events, or the development of a clinic for patients with chronic stable angina, VA HCPs are focused on meeting the demanding health care needs of veterans.2-4

Federal Practitioner will continue to highlight the great work that is being done across the federal health care system, even when it is not popular. The benefits of the medical research and health care innovations are shared by all Americans. They have earned our trust and respect. So, let us know what you think (email or Facebook), and please continue to share your experiences serving your patients. That’s why we’re here.

Author disclosures
The author reports no actual or potential conflicts of interest with regard to this article.

Being in the political crossfire is nothing new to the VA. The largest health care organization in the U.S. has seen its share of firestorms. And that’s okay. Transparency is essential for maintaining the public trust.

The mission to care for veterans and their families is one that the overwhelming majority of the 280,000 VA employees take extremely seriously. The reports of excessive wait times for veterans seeking care are disturbing to everyone inside and outside the VA. We fully expect the new Secretary of Veterans Affairs will act quickly to ensure that all veterans receive the care they deserve in a timely fashion.

Nevertheless, we remain concerned that the current climate may erode the trust that VA health care providers (HCPs) have earned. The vast majority continue to deliver high-quality care to a particularly vulnerable population. According to the latest American Customer Satisfaction Index, veterans are satisfied with the quality of care they receive at VA facilities. The VA, in fact, gets higher marks for its service than most other government agencies.1

As President Obama insisted in a May press conference: “Every single day, there are people working in the VA who do outstanding work and put everything they’ve got into making sure that our veterans get the care, benefits, and services that they need.” Unfortunately, not all critics recognize that commitment.

They should. There is important work being done by VA HCPs. For more than 30 years, Federal Practitioner has showcased the dedication of the men and women who deliver health care across government agencies. The VA has been the source of many important innovations over the years, like recognizing the importance of nurse practitioners in health care delivery. The VA Computerized Patient Record System exemplifies how an electronic health record system can improve health care.

We talk to many at the VA who are committed to sharing best practices, difficult case studies, and innovative programs, which often exist only because of the dedication and commitment of passionate HCPs. For example, Dr. Dewleen Baker of the VA San Diego Healthcare System who wanted to understand the causes of posttraumatic stress disorder (PTSD) and traumatic brain injuries (TBIs) in the military and among veterans. Rather than waiting until veterans came in the door, Dr. Baker created a massive study in cooperation with the U.S. Marines and Navy so that subjects could have baseline evaluations before deployment and could be monitored throughout their lives. The results of the study may provide essential insight into PTSD and TBI and will benefit not only veterans, but all patients.

Veterans do, in fact, have unique concerns and deserve an agency focused on their care. Too many veterans, for example, return from their service with a desperate need for palliative care and prescriptions for opioids. Replacing pain with addiction, however, remains a significant concern. In response, the VA Pharmacy Benefit Management Service developed an opioid monitoring dashboard to improve prescribing practices and reduce the use of opioids. The dashboard allows the VA to both see patterns across the entire system and to make exceptions for individual veterans, ensuring that each veteran gets exactly the care he or she needs.

Every issue of Federal Practitioner is replete with similar examples of HCPs who provide the best care possible within the budget constraints set by Congress. Whether it’s the development of an e-consult program to speed access to diabetes specialists, a training program on how to disclose adverse events, or the development of a clinic for patients with chronic stable angina, VA HCPs are focused on meeting the demanding health care needs of veterans.2-4

Federal Practitioner will continue to highlight the great work that is being done across the federal health care system, even when it is not popular. The benefits of the medical research and health care innovations are shared by all Americans. They have earned our trust and respect. So, let us know what you think (email or Facebook), and please continue to share your experiences serving your patients. That’s why we’re here.

Author disclosures
The author reports no actual or potential conflicts of interest with regard to this article.

References

 1. American Customer Satisfaction Index. ACSI Benchmarks for U.S. Federal Government 2013. http://www.theacsi.org/acsi-benchmarks-for-u-s-federal-government-2013. Published January 28, 2014. Accessed May 28, 2014.

 2. Vasudevan MM, Hurr SD, Green MC, et al. The clinical impact of electronic consultation in diabetes care. Fed Pract. 2014;31(3):32-36.

 3. Dunn EJ, McKinney KM, Martin ME. Empathic disclosure of adverse events to patients. Fed Pract. 2014;31(5):18-21.

 4. Gillette MA, Frohnapple DJ, Knott A, Reeder D. Pharmacist-managed collaborative practice for chronic stable angina. Fed Pract. 2014;31(6):16-22.

References

 1. American Customer Satisfaction Index. ACSI Benchmarks for U.S. Federal Government 2013. http://www.theacsi.org/acsi-benchmarks-for-u-s-federal-government-2013. Published January 28, 2014. Accessed May 28, 2014.

 2. Vasudevan MM, Hurr SD, Green MC, et al. The clinical impact of electronic consultation in diabetes care. Fed Pract. 2014;31(3):32-36.

 3. Dunn EJ, McKinney KM, Martin ME. Empathic disclosure of adverse events to patients. Fed Pract. 2014;31(5):18-21.

 4. Gillette MA, Frohnapple DJ, Knott A, Reeder D. Pharmacist-managed collaborative practice for chronic stable angina. Fed Pract. 2014;31(6):16-22.

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