An Algorithm for Managing Spitting Sutures

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Practice Gap

It is well established that surgical complications and a poor scar outcome can have a remarkable impact on patient satisfaction.1 A common complication following dermatologic surgery is suture spitting, in which a buried suture is extruded through the skin surface. When repairing a cutaneous defect following dermatologic surgery, absorbable or nonabsorbable sutures are placed under the skin surface to approximate wound edges, eliminate dead space, and reduce tension on the edges of the wound, improving the cosmetic outcomes.

Absorbable sutures constitute most buried sutures in cutaneous surgery and can be made of natural or synthetic fibers.2 Absorbable sutures made from synthetic fibers are degraded by hydrolysis, in which water breaks down polymer chains of the suture filament. Natural absorbable sutures are composed of mammalian collagen; they are broken down by the enzymatic process of proteolysis.

Tensile strength is lost long before a suture is fully absorbed. Although synthetic fibers have, in general, higher tensile strength and generate less tissue inflammation, they take much longer to absorb.2 During absorption, in some cases, a buried suture is pushed to the surface and extrudes along the wound edge or scar, which is known as spitting3 (Figure 1).

Figure 1. Spitting sutures (black arrows) developed 3 months after closure of a Mohs micrographic surgery defect on the left cheek.


Suture spitting typically occurs in the 2-week to 3-month postoperative period. However, with the use of long-lasting absorbable or nonabsorbable sutures, spitting can occur several months or years postoperatively. Spitting sutures often are associated with surrounding erythema, edema, discharge, and a foreign-body sensation4—symptoms that can be highly distressing to the patient and can lead to postoperative infection or stitch abscess.3

Herein, we review techniques that can decrease the risk for suture spitting, and we present a stepwise approach to managing this common problem.

The Technique

Choice of suture material for buried sutures can influence the risk of spitting.

Factors Impacting Increased Spitting
The 3 most common absorbable sutures in dermatologic surgery include poliglecaprone 25, polyglactin 910, and polydioxanone; of them, polyglactin 910 has been found to have a higher rate of spitting than poliglecaprone 25 and polydioxanone.2 However, because complete absorption of polydioxanone can take as long as 8 months, this suture might “spit” much later than polyglactin 910 or poliglecaprone 25, which typically are fully hydrolyzed by 3 and 4 months, respectively.2 Placing sutures superficially in the dermis has been found to increase the rate of spitting.5 Throwing more knots per closure also has been found to increase the rate of spitting.5

How to Decrease Spitting
Careful choice of suture material and proper depth of suture placement might decrease the risk for spitting in dermatologic surgery. Furthermore, if polyglactin 910 or a long-lasting suture is to be used, sutures should be placed deeply.

What to Do If Sutures Spit
When a suture has begun to spit, the extruding foreign material needs to be removed and the surgical site assessed for infection or abscess. Exposed suture material typically can be removed with forceps without local anesthesia. In some cases, fine-tipped Bishop-Harmon tissue forceps or jewelers forceps might be required.

If the suture cannot be removed completely, it should be trimmed as short as possible. This can be accomplished by pulling on the exposed end of the suture, tenting the skin, and trimming it as close as possible to the surface. Once the foreign material is removed, assessment for signs of infection is paramount.

How to Manage Infection—Postoperative infection associated with a spitting suture can take the form of a periwound cellulitis or stitch abscess.3 A stitch abscess can reflect a sterile inflammatory response to the buried suture or a true infection4; the former is more common.3 In the event of an infected stitch abscess, provide warm compresses, obtain specimens for culture, and prescribe antibiotics after the spitting suture has been removed. Incision and drainage also might be required if notable fluctuance is present.



It is crucial for dermatologic surgeons to identify and manage these complications. Figure 2 illustrates an algorithmic approach to managing spitting sutures.

Practical Implications

Spitting sutures are a common occurrence following dermatologic surgery that can lead to remarkable patient distress. Fortunately, in the absence of superimposed infection, spitting sutures have not been shown to worsen outcomes of healing and scarring.5 Nevertheless, it is important to identify and appropriately treat this common complication. The simple algorithm we provide (Figure 2) aids in cutaneous surgery by providing a straightforward approach to managing spitting sutures and their complications.

Figure 2. Management of a spitting suture.

References
  1. Balaraman B, Geddes ER, Friedman PM. Best reconstructive techniques: improving the final scar. Dermatol Surg. 2015;41(suppl 10):S265-S275. doi:10.1097/DSS.0000000000000496
  2. Yag-Howard C. Sutures, needles, and tissue adhesives: a review for dermatologic surgery. Dermatol Surg. 2014;40(suppl 9):S3-S15. doi:10.1097/01.DSS.0000452738.23278.2d
  3. Gloster HM. Complications in Cutaneous Surgery. Springer; 2011.
  4. Slutsky JB, Fosko ST. Complications in Mohs surgery. In: Berlin A, ed. Mohs and Cutaneous Surgery: Maximizing Aesthetic Outcomes. CRC Press; 2015:55-89.
  5. Kim B, Sgarioto M, Hewitt D, et al. Scar outcomes in dermatological surgery. Australas J Dermatol. 2018;59:48-51. doi:10.1111/ajd.12570
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From the Department of Dermatology, The University of Texas Medical Branch, Galveston.

The authors report no conflict of interest.

Correspondence: Frank Winsett, MD, Department of Dermatology, 301 University Blvd, 4.112, McCullough Building, Galveston, TX 77555-0783 ([email protected]).

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Author and Disclosure Information

From the Department of Dermatology, The University of Texas Medical Branch, Galveston.

The authors report no conflict of interest.

Correspondence: Frank Winsett, MD, Department of Dermatology, 301 University Blvd, 4.112, McCullough Building, Galveston, TX 77555-0783 ([email protected]).

Article PDF
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Practice Gap

It is well established that surgical complications and a poor scar outcome can have a remarkable impact on patient satisfaction.1 A common complication following dermatologic surgery is suture spitting, in which a buried suture is extruded through the skin surface. When repairing a cutaneous defect following dermatologic surgery, absorbable or nonabsorbable sutures are placed under the skin surface to approximate wound edges, eliminate dead space, and reduce tension on the edges of the wound, improving the cosmetic outcomes.

Absorbable sutures constitute most buried sutures in cutaneous surgery and can be made of natural or synthetic fibers.2 Absorbable sutures made from synthetic fibers are degraded by hydrolysis, in which water breaks down polymer chains of the suture filament. Natural absorbable sutures are composed of mammalian collagen; they are broken down by the enzymatic process of proteolysis.

Tensile strength is lost long before a suture is fully absorbed. Although synthetic fibers have, in general, higher tensile strength and generate less tissue inflammation, they take much longer to absorb.2 During absorption, in some cases, a buried suture is pushed to the surface and extrudes along the wound edge or scar, which is known as spitting3 (Figure 1).

Figure 1. Spitting sutures (black arrows) developed 3 months after closure of a Mohs micrographic surgery defect on the left cheek.


Suture spitting typically occurs in the 2-week to 3-month postoperative period. However, with the use of long-lasting absorbable or nonabsorbable sutures, spitting can occur several months or years postoperatively. Spitting sutures often are associated with surrounding erythema, edema, discharge, and a foreign-body sensation4—symptoms that can be highly distressing to the patient and can lead to postoperative infection or stitch abscess.3

Herein, we review techniques that can decrease the risk for suture spitting, and we present a stepwise approach to managing this common problem.

The Technique

Choice of suture material for buried sutures can influence the risk of spitting.

Factors Impacting Increased Spitting
The 3 most common absorbable sutures in dermatologic surgery include poliglecaprone 25, polyglactin 910, and polydioxanone; of them, polyglactin 910 has been found to have a higher rate of spitting than poliglecaprone 25 and polydioxanone.2 However, because complete absorption of polydioxanone can take as long as 8 months, this suture might “spit” much later than polyglactin 910 or poliglecaprone 25, which typically are fully hydrolyzed by 3 and 4 months, respectively.2 Placing sutures superficially in the dermis has been found to increase the rate of spitting.5 Throwing more knots per closure also has been found to increase the rate of spitting.5

How to Decrease Spitting
Careful choice of suture material and proper depth of suture placement might decrease the risk for spitting in dermatologic surgery. Furthermore, if polyglactin 910 or a long-lasting suture is to be used, sutures should be placed deeply.

What to Do If Sutures Spit
When a suture has begun to spit, the extruding foreign material needs to be removed and the surgical site assessed for infection or abscess. Exposed suture material typically can be removed with forceps without local anesthesia. In some cases, fine-tipped Bishop-Harmon tissue forceps or jewelers forceps might be required.

If the suture cannot be removed completely, it should be trimmed as short as possible. This can be accomplished by pulling on the exposed end of the suture, tenting the skin, and trimming it as close as possible to the surface. Once the foreign material is removed, assessment for signs of infection is paramount.

How to Manage Infection—Postoperative infection associated with a spitting suture can take the form of a periwound cellulitis or stitch abscess.3 A stitch abscess can reflect a sterile inflammatory response to the buried suture or a true infection4; the former is more common.3 In the event of an infected stitch abscess, provide warm compresses, obtain specimens for culture, and prescribe antibiotics after the spitting suture has been removed. Incision and drainage also might be required if notable fluctuance is present.



It is crucial for dermatologic surgeons to identify and manage these complications. Figure 2 illustrates an algorithmic approach to managing spitting sutures.

Practical Implications

Spitting sutures are a common occurrence following dermatologic surgery that can lead to remarkable patient distress. Fortunately, in the absence of superimposed infection, spitting sutures have not been shown to worsen outcomes of healing and scarring.5 Nevertheless, it is important to identify and appropriately treat this common complication. The simple algorithm we provide (Figure 2) aids in cutaneous surgery by providing a straightforward approach to managing spitting sutures and their complications.

Figure 2. Management of a spitting suture.

 

Practice Gap

It is well established that surgical complications and a poor scar outcome can have a remarkable impact on patient satisfaction.1 A common complication following dermatologic surgery is suture spitting, in which a buried suture is extruded through the skin surface. When repairing a cutaneous defect following dermatologic surgery, absorbable or nonabsorbable sutures are placed under the skin surface to approximate wound edges, eliminate dead space, and reduce tension on the edges of the wound, improving the cosmetic outcomes.

Absorbable sutures constitute most buried sutures in cutaneous surgery and can be made of natural or synthetic fibers.2 Absorbable sutures made from synthetic fibers are degraded by hydrolysis, in which water breaks down polymer chains of the suture filament. Natural absorbable sutures are composed of mammalian collagen; they are broken down by the enzymatic process of proteolysis.

Tensile strength is lost long before a suture is fully absorbed. Although synthetic fibers have, in general, higher tensile strength and generate less tissue inflammation, they take much longer to absorb.2 During absorption, in some cases, a buried suture is pushed to the surface and extrudes along the wound edge or scar, which is known as spitting3 (Figure 1).

Figure 1. Spitting sutures (black arrows) developed 3 months after closure of a Mohs micrographic surgery defect on the left cheek.


Suture spitting typically occurs in the 2-week to 3-month postoperative period. However, with the use of long-lasting absorbable or nonabsorbable sutures, spitting can occur several months or years postoperatively. Spitting sutures often are associated with surrounding erythema, edema, discharge, and a foreign-body sensation4—symptoms that can be highly distressing to the patient and can lead to postoperative infection or stitch abscess.3

Herein, we review techniques that can decrease the risk for suture spitting, and we present a stepwise approach to managing this common problem.

The Technique

Choice of suture material for buried sutures can influence the risk of spitting.

Factors Impacting Increased Spitting
The 3 most common absorbable sutures in dermatologic surgery include poliglecaprone 25, polyglactin 910, and polydioxanone; of them, polyglactin 910 has been found to have a higher rate of spitting than poliglecaprone 25 and polydioxanone.2 However, because complete absorption of polydioxanone can take as long as 8 months, this suture might “spit” much later than polyglactin 910 or poliglecaprone 25, which typically are fully hydrolyzed by 3 and 4 months, respectively.2 Placing sutures superficially in the dermis has been found to increase the rate of spitting.5 Throwing more knots per closure also has been found to increase the rate of spitting.5

How to Decrease Spitting
Careful choice of suture material and proper depth of suture placement might decrease the risk for spitting in dermatologic surgery. Furthermore, if polyglactin 910 or a long-lasting suture is to be used, sutures should be placed deeply.

What to Do If Sutures Spit
When a suture has begun to spit, the extruding foreign material needs to be removed and the surgical site assessed for infection or abscess. Exposed suture material typically can be removed with forceps without local anesthesia. In some cases, fine-tipped Bishop-Harmon tissue forceps or jewelers forceps might be required.

If the suture cannot be removed completely, it should be trimmed as short as possible. This can be accomplished by pulling on the exposed end of the suture, tenting the skin, and trimming it as close as possible to the surface. Once the foreign material is removed, assessment for signs of infection is paramount.

How to Manage Infection—Postoperative infection associated with a spitting suture can take the form of a periwound cellulitis or stitch abscess.3 A stitch abscess can reflect a sterile inflammatory response to the buried suture or a true infection4; the former is more common.3 In the event of an infected stitch abscess, provide warm compresses, obtain specimens for culture, and prescribe antibiotics after the spitting suture has been removed. Incision and drainage also might be required if notable fluctuance is present.



It is crucial for dermatologic surgeons to identify and manage these complications. Figure 2 illustrates an algorithmic approach to managing spitting sutures.

Practical Implications

Spitting sutures are a common occurrence following dermatologic surgery that can lead to remarkable patient distress. Fortunately, in the absence of superimposed infection, spitting sutures have not been shown to worsen outcomes of healing and scarring.5 Nevertheless, it is important to identify and appropriately treat this common complication. The simple algorithm we provide (Figure 2) aids in cutaneous surgery by providing a straightforward approach to managing spitting sutures and their complications.

Figure 2. Management of a spitting suture.

References
  1. Balaraman B, Geddes ER, Friedman PM. Best reconstructive techniques: improving the final scar. Dermatol Surg. 2015;41(suppl 10):S265-S275. doi:10.1097/DSS.0000000000000496
  2. Yag-Howard C. Sutures, needles, and tissue adhesives: a review for dermatologic surgery. Dermatol Surg. 2014;40(suppl 9):S3-S15. doi:10.1097/01.DSS.0000452738.23278.2d
  3. Gloster HM. Complications in Cutaneous Surgery. Springer; 2011.
  4. Slutsky JB, Fosko ST. Complications in Mohs surgery. In: Berlin A, ed. Mohs and Cutaneous Surgery: Maximizing Aesthetic Outcomes. CRC Press; 2015:55-89.
  5. Kim B, Sgarioto M, Hewitt D, et al. Scar outcomes in dermatological surgery. Australas J Dermatol. 2018;59:48-51. doi:10.1111/ajd.12570
References
  1. Balaraman B, Geddes ER, Friedman PM. Best reconstructive techniques: improving the final scar. Dermatol Surg. 2015;41(suppl 10):S265-S275. doi:10.1097/DSS.0000000000000496
  2. Yag-Howard C. Sutures, needles, and tissue adhesives: a review for dermatologic surgery. Dermatol Surg. 2014;40(suppl 9):S3-S15. doi:10.1097/01.DSS.0000452738.23278.2d
  3. Gloster HM. Complications in Cutaneous Surgery. Springer; 2011.
  4. Slutsky JB, Fosko ST. Complications in Mohs surgery. In: Berlin A, ed. Mohs and Cutaneous Surgery: Maximizing Aesthetic Outcomes. CRC Press; 2015:55-89.
  5. Kim B, Sgarioto M, Hewitt D, et al. Scar outcomes in dermatological surgery. Australas J Dermatol. 2018;59:48-51. doi:10.1111/ajd.12570
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Wound Healing on the Dorsal Hands: An Intrapatient Comparison of Primary Closure, Purse-String Closure, and Secondary Intention

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Practice Gap

Many cutaneous surgery wounds can be closed primarily; however, in certain cases, other repair options might be appropriate and should be evaluated on a case-by-case basis with input from the patient. Defects on the dorsal aspect of the hands—where nonmelanoma skin cancer is common and reserve tissue is limited—often heal by secondary intention with good cosmetic and functional results. Patients often express a desire to reduce the time spent in the surgical suite and restrictions on postoperative activity, making secondary intention healing more appealing. An additional advantage is obviation of the need to remove additional tissue in the form of Burow triangles, which would lead to a longer wound. The major disadvantage of secondary intention healing is longer time to wound maturity; we often minimize this disadvantage with purse-string closure to decrease the size of the wound defect, which can be done quickly and without removing additional tissue.

The Technique

An elderly man had 3 nonmelanoma skin cancers—all on the dorsal aspect of the left hand—that were treated on the same day, leaving 3 similar wound defects after Mohs micrographic surgery. The wound defects (distal to proximal) measured 12 mm, 12 mm, and 10 mm in diameter (Figure 1) and were repaired by primary closure, secondary intention, and purse-string circumferential closure, respectively. Purse-string closure1 was performed with a 4-0 polyglactin 901 suture and left to heal without external sutures (Figure 2). Figure 3 shows the 3 types of repairs immediately following closure. All wounds healed with excellent and essentially equivalent cosmetic results, with excellent patient satisfaction at 6-month follow-up (Figure 4).

Figure 1. Wounds prior to closure.

Figure 2. A dermal purse-string closure suture pathway was used for one of the wounds to reduce wound size.

Figure 3. Wounds immediately following repair (distal to proximal: linear closure, secondary intention, purse-string closure).

Figure 4. At 6-month follow-up, there was essentially no difference in the appearance of the 3 wounds.

Practical Implications

Our case illustrates different modalities of wound repair during precisely the same time frame and essentially on the same location. Skin of the dorsal hand often is tight; depending on the size of the defect, large primary closure can be tedious to perform, can lead to increased wound tension and risk of dehiscence, and can be uncomfortable for the patient during healing. However, primary closure typically will lead to faster healing.

Secondary intention healing and purse-string closure require less surgery and therefore cost less; these modalities yield similar cosmesis and satisfaction. In the appropriate context, secondary intention has been highlighted as a suitable alternative to primary closure2-4; in our experience (and that of others5), patient satisfaction is not diminished with healing by secondary intention. Purse-string closure also can minimize wound size and healing time.

For small shallow wounds on the dorsal hand, dermatologic surgeons should have confidence that secondary intention healing, with or without wound reduction using purse-string repair, likely will lead to acceptable cosmetic and functional results. Of course, repair should be tailored to the circumstances and wishes of the individual patient.

References
  1. Peled IJ, Zagher U, Wexler MR. Purse-string suture for reduction and closure of skin defects. Ann Plast Surg. 1985;14:465-469. doi:10.1097/00000637-198505000-00012
  2. Zitelli JA. Secondary intention healing: an alternative to surgical repair. Clin Dermatol. 1984;2:92-106. doi:10.1016/0738-081x(84)90031-2
  3. Fazio MJ, Zitelli JA. Principles of reconstruction following excision of nonmelanoma skin cancer. Clin Dermatol. 1995;13:601-616. doi:10.1016/0738-081x(95)00099-2
  4. Bosley R, Leithauser L, Turner M, et al. The efficacy of second-intention healing in the management of defects on the dorsal surface of the hands and fingers after Mohs micrographic surgery. Dermatol Surg. 2012;38:647-653. doi:10.1111/j.1524-4725.2011.02258.x
  5. Stebbins WG, Gusev J, Higgins HW 2nd, et al. Evaluation of patient satisfaction with second intention healing versus primary surgical closure. J Am Acad Dermatol. 2015;73:865-867.e1. doi:10.1016/j.jaad.2015.07.019
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The authors report no conflict of interest.

Correspondence: Jayson Miedema, MD, 410 Market St, Ste 400, Chapel Hill, NC 27516 ([email protected]).

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The authors report no conflict of interest.

Correspondence: Jayson Miedema, MD, 410 Market St, Ste 400, Chapel Hill, NC 27516 ([email protected]).

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Drs. Miedema and Varma are from the Department of Dermatology, University of North Carolina at Chapel Hill. Dr. Miedema also is from the Department of Pathology. Dr. Hsia is from the Department of Dermatology, Medical University of South Carolina, Charleston.

The authors report no conflict of interest.

Correspondence: Jayson Miedema, MD, 410 Market St, Ste 400, Chapel Hill, NC 27516 ([email protected]).

Article PDF
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Practice Gap

Many cutaneous surgery wounds can be closed primarily; however, in certain cases, other repair options might be appropriate and should be evaluated on a case-by-case basis with input from the patient. Defects on the dorsal aspect of the hands—where nonmelanoma skin cancer is common and reserve tissue is limited—often heal by secondary intention with good cosmetic and functional results. Patients often express a desire to reduce the time spent in the surgical suite and restrictions on postoperative activity, making secondary intention healing more appealing. An additional advantage is obviation of the need to remove additional tissue in the form of Burow triangles, which would lead to a longer wound. The major disadvantage of secondary intention healing is longer time to wound maturity; we often minimize this disadvantage with purse-string closure to decrease the size of the wound defect, which can be done quickly and without removing additional tissue.

The Technique

An elderly man had 3 nonmelanoma skin cancers—all on the dorsal aspect of the left hand—that were treated on the same day, leaving 3 similar wound defects after Mohs micrographic surgery. The wound defects (distal to proximal) measured 12 mm, 12 mm, and 10 mm in diameter (Figure 1) and were repaired by primary closure, secondary intention, and purse-string circumferential closure, respectively. Purse-string closure1 was performed with a 4-0 polyglactin 901 suture and left to heal without external sutures (Figure 2). Figure 3 shows the 3 types of repairs immediately following closure. All wounds healed with excellent and essentially equivalent cosmetic results, with excellent patient satisfaction at 6-month follow-up (Figure 4).

Figure 1. Wounds prior to closure.

Figure 2. A dermal purse-string closure suture pathway was used for one of the wounds to reduce wound size.

Figure 3. Wounds immediately following repair (distal to proximal: linear closure, secondary intention, purse-string closure).

Figure 4. At 6-month follow-up, there was essentially no difference in the appearance of the 3 wounds.

Practical Implications

Our case illustrates different modalities of wound repair during precisely the same time frame and essentially on the same location. Skin of the dorsal hand often is tight; depending on the size of the defect, large primary closure can be tedious to perform, can lead to increased wound tension and risk of dehiscence, and can be uncomfortable for the patient during healing. However, primary closure typically will lead to faster healing.

Secondary intention healing and purse-string closure require less surgery and therefore cost less; these modalities yield similar cosmesis and satisfaction. In the appropriate context, secondary intention has been highlighted as a suitable alternative to primary closure2-4; in our experience (and that of others5), patient satisfaction is not diminished with healing by secondary intention. Purse-string closure also can minimize wound size and healing time.

For small shallow wounds on the dorsal hand, dermatologic surgeons should have confidence that secondary intention healing, with or without wound reduction using purse-string repair, likely will lead to acceptable cosmetic and functional results. Of course, repair should be tailored to the circumstances and wishes of the individual patient.

 

Practice Gap

Many cutaneous surgery wounds can be closed primarily; however, in certain cases, other repair options might be appropriate and should be evaluated on a case-by-case basis with input from the patient. Defects on the dorsal aspect of the hands—where nonmelanoma skin cancer is common and reserve tissue is limited—often heal by secondary intention with good cosmetic and functional results. Patients often express a desire to reduce the time spent in the surgical suite and restrictions on postoperative activity, making secondary intention healing more appealing. An additional advantage is obviation of the need to remove additional tissue in the form of Burow triangles, which would lead to a longer wound. The major disadvantage of secondary intention healing is longer time to wound maturity; we often minimize this disadvantage with purse-string closure to decrease the size of the wound defect, which can be done quickly and without removing additional tissue.

The Technique

An elderly man had 3 nonmelanoma skin cancers—all on the dorsal aspect of the left hand—that were treated on the same day, leaving 3 similar wound defects after Mohs micrographic surgery. The wound defects (distal to proximal) measured 12 mm, 12 mm, and 10 mm in diameter (Figure 1) and were repaired by primary closure, secondary intention, and purse-string circumferential closure, respectively. Purse-string closure1 was performed with a 4-0 polyglactin 901 suture and left to heal without external sutures (Figure 2). Figure 3 shows the 3 types of repairs immediately following closure. All wounds healed with excellent and essentially equivalent cosmetic results, with excellent patient satisfaction at 6-month follow-up (Figure 4).

Figure 1. Wounds prior to closure.

Figure 2. A dermal purse-string closure suture pathway was used for one of the wounds to reduce wound size.

Figure 3. Wounds immediately following repair (distal to proximal: linear closure, secondary intention, purse-string closure).

Figure 4. At 6-month follow-up, there was essentially no difference in the appearance of the 3 wounds.

Practical Implications

Our case illustrates different modalities of wound repair during precisely the same time frame and essentially on the same location. Skin of the dorsal hand often is tight; depending on the size of the defect, large primary closure can be tedious to perform, can lead to increased wound tension and risk of dehiscence, and can be uncomfortable for the patient during healing. However, primary closure typically will lead to faster healing.

Secondary intention healing and purse-string closure require less surgery and therefore cost less; these modalities yield similar cosmesis and satisfaction. In the appropriate context, secondary intention has been highlighted as a suitable alternative to primary closure2-4; in our experience (and that of others5), patient satisfaction is not diminished with healing by secondary intention. Purse-string closure also can minimize wound size and healing time.

For small shallow wounds on the dorsal hand, dermatologic surgeons should have confidence that secondary intention healing, with or without wound reduction using purse-string repair, likely will lead to acceptable cosmetic and functional results. Of course, repair should be tailored to the circumstances and wishes of the individual patient.

References
  1. Peled IJ, Zagher U, Wexler MR. Purse-string suture for reduction and closure of skin defects. Ann Plast Surg. 1985;14:465-469. doi:10.1097/00000637-198505000-00012
  2. Zitelli JA. Secondary intention healing: an alternative to surgical repair. Clin Dermatol. 1984;2:92-106. doi:10.1016/0738-081x(84)90031-2
  3. Fazio MJ, Zitelli JA. Principles of reconstruction following excision of nonmelanoma skin cancer. Clin Dermatol. 1995;13:601-616. doi:10.1016/0738-081x(95)00099-2
  4. Bosley R, Leithauser L, Turner M, et al. The efficacy of second-intention healing in the management of defects on the dorsal surface of the hands and fingers after Mohs micrographic surgery. Dermatol Surg. 2012;38:647-653. doi:10.1111/j.1524-4725.2011.02258.x
  5. Stebbins WG, Gusev J, Higgins HW 2nd, et al. Evaluation of patient satisfaction with second intention healing versus primary surgical closure. J Am Acad Dermatol. 2015;73:865-867.e1. doi:10.1016/j.jaad.2015.07.019
References
  1. Peled IJ, Zagher U, Wexler MR. Purse-string suture for reduction and closure of skin defects. Ann Plast Surg. 1985;14:465-469. doi:10.1097/00000637-198505000-00012
  2. Zitelli JA. Secondary intention healing: an alternative to surgical repair. Clin Dermatol. 1984;2:92-106. doi:10.1016/0738-081x(84)90031-2
  3. Fazio MJ, Zitelli JA. Principles of reconstruction following excision of nonmelanoma skin cancer. Clin Dermatol. 1995;13:601-616. doi:10.1016/0738-081x(95)00099-2
  4. Bosley R, Leithauser L, Turner M, et al. The efficacy of second-intention healing in the management of defects on the dorsal surface of the hands and fingers after Mohs micrographic surgery. Dermatol Surg. 2012;38:647-653. doi:10.1111/j.1524-4725.2011.02258.x
  5. Stebbins WG, Gusev J, Higgins HW 2nd, et al. Evaluation of patient satisfaction with second intention healing versus primary surgical closure. J Am Acad Dermatol. 2015;73:865-867.e1. doi:10.1016/j.jaad.2015.07.019
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Reconstruction Technique for Defects of the Cutaneous and Mucosal Lip: V-to-flying-Y Closure

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Practice Gap

Reconstruction of a lip defect poses challenges to the dermatologic surgeon. The lip is a free margin, where excess tension can cause noticeable distortion in facial aesthetics. Distortion of that free margin might not only disrupt the appearance of the lip but affect function by impairing oral competency and mobility; therefore, when choosing a method of reconstruction, the surgeon must take free margin distortion into account. Misalignment of the vermilion border upon reconstruction will cause a poor aesthetic result in the absence of free margin distortion. When a surgical defect involves more than one cosmetic subunit of the lip, great care must be taken to repair each subunit individually to achieve the best cosmetic and functional results.

The suitability of traditional approaches to reconstruction of a defect that crosses the vermilion border—healing by secondary intention, primary linear repair, full-thickness wedge repair, partial-thickness wedge repair, and combined cutaneous and mucosal advancement1—depends on the depth of the lesion.

Clinical Presentation

A 66-year-old woman with a 4×6-mm, invasive, well-differentiated squamous cell carcinoma of the left lower lip was referred for Mohs micrographic surgery. Removal of the tumor required 2 stages to obtain clear margins, leaving a 1.0×1.2-cm defect that crossed the vermilion border (Figure, A). How would you repair this defect?

A, A 1×1.2-cm defect of the lower lip, involving the vermilion and cutaneous lip. The vermilion border is outlined prior to the start of extirpation of the tumor. B, Illustration of the proposed incision lines and direction of tissue movement (arrow). C, Completed repair, demonstrating proper placement of the vermilion border and lack of displacement of the lip. D, At 11-month follow-up, there is no distortion of the vermilion border. The patient reports no functional deficit.

Selecting a Technique to Close the Surgical Defect

For this patient, we had several options to consider in approaching closure, including several that we rejected. Because the defect crossed cosmetic subunit boundaries, healing by secondary intention was avoided, as it would cause contraction, obliterate the vermilion border, and result in poor functional and cosmetic results. We decided against primary closure, even with careful attention to reapproximation of the vermilion border, because the width of the defect would have required a large Burow triangle that extended into the oral cavity. For defects less than one-third the width of the lip, full-thickness wedge repair can yield excellent cosmetic results but, in this case, would decrease the oral aperture and was deemed too extensive a procedure for a relatively shallow defect.2

Instead, we chose to perform repair with V to Y advancement of skin below the cutaneous defect, up to the location of the absent vermilion border, combined with small, horizontal, linear closure of the mucosal portion of the defect. This approach is a variation of a repair described by Jin et al,3 who described using 2 opposing V-Y advancement flaps to repair defects of the lip. This repair has provided excellent cosmetic results for a small series of our patients, preserving the oral aperture and maintaining the important aesthetic location of the vermilion border. In addition, the technique makes it unnecessary for the patient to undergo a much larger repair, such as a full- or partial-thickness wedge when the initial defect is relatively shallow.

Closure Technique

It is essential to properly outline the vermilion border of the lip before initiating the repair, ideally before any infiltration of local anesthesia if the surgeon anticipates that tumor extirpation might cross the vermilion border.

Repair
Closing then proceeds as follows:

• The cutaneous portion of the defect is drawn out in standard V to Y fashion, carrying the incision through the dermis and into subcutaneous tissue. The pedicle of the flap is maintained at the base of the island, serving as the blood supply to the flap.

• The periphery of the flap and surrounding tissue is undermined to facilitate movement superiorly into the cutaneous portion of the defect.

• A single buried vertical mattress suture can be placed at the advancing border of the island, holding it in place at the anticipated location of the vermilion border. The secondary defect created by the advancing V is closed to help push the island into place and prevent downward tension on the free margin of the lip.

• The remaining defect of the vermilion lip is closed by removing Burow triangles at the horizontal edges on each side of the remaining defect (Figure, B). The triangles are removed completely within the mucosal lip, with the inferior edge of the triangle placed at the vermilion border.

• The defect is closed in a primary linear horizontal fashion, using buried vertical mattress sutures and cutaneous approximation.

The final appearance of the sutured defect yields a small lateral extension at the superior edge of the V to Y closure, giving the appearance of wings on the Y, prompting us to term the closure V-to-flying-Y (Figure, C).

Although the limited portion of the mucosal lip that is closed in this fashion might appear thinner than the remaining lip, it generally yields a cosmetically acceptable result in the properly selected patient. Our experience also has shown an improvement in this difference in the months following repair. A full mucosal advancement flap might result in a more uniform appearance of the lower lip, but it is a larger and more difficult procedure for the patient to endure. Additionally, a full mucosal advancement flap risks uniformly creating a much thinner lip.



Postoperative Course
Sutures were removed 1 week postoperatively. Proper location of the vermilion border, without distortion of the free margin, was demonstrated. At 11-month follow-up, excellent cosmetic and functional results were noted (Figure, D).

Practice Implications

This repair (1) demonstrates an elegant method of closing a relatively shallow defect that crosses the vermilion border and (2) allows the surgeon to address each cosmetic subunit individually. We have found that this repair provides excellent cosmetic and functional results, with little morbidity.

The lip is a common site of nonmelanoma squamous cell carcinoma. Poorly planned closing after excision of the tumor risks notable impairment of function or cosmetic distortion. When a defect of the lip crosses cosmetic subunits, it is helpful to repair each subunit individually. V-to-flying-Y closure is an effective method to close defects that cross the vermilion border, resulting in well-preserved cosmetic appearance and function.

References
  1. Ishii LE, Byrne PJ. Lip reconstruction. Facial Plast Surg Clin North Am. 2009;17:445-453. doi:10.1016/j.fsc.2009.05.007
  2. Sebben JE. Wedge resection of the lip: minimizing problems. J Dermatol Surg Oncol. 1985;11:60-64. doi:10.1111/j.1524-4725.1985.tb02892.x
  3. Jin X, Teng L, Zhang C, et al. Reconstruction of partial-thickness vermilion defects with a mucosal V-Y advancement flap based on the orbicularis oris muscle. J Plast Reconstr Aesthet Surg. 2011;64:472-476. doi:10.1016/j.bjps.2010.07.017
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From Beaumont Health Dermatology, Trenton, Michigan.

The authors report no conflict of interest.

Correspondence: Stetson Albertson, DO, Beaumont Health Dermatology, 5450 Fort St, Trenton, MI 48183 ([email protected]). 

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Practice Gap

Reconstruction of a lip defect poses challenges to the dermatologic surgeon. The lip is a free margin, where excess tension can cause noticeable distortion in facial aesthetics. Distortion of that free margin might not only disrupt the appearance of the lip but affect function by impairing oral competency and mobility; therefore, when choosing a method of reconstruction, the surgeon must take free margin distortion into account. Misalignment of the vermilion border upon reconstruction will cause a poor aesthetic result in the absence of free margin distortion. When a surgical defect involves more than one cosmetic subunit of the lip, great care must be taken to repair each subunit individually to achieve the best cosmetic and functional results.

The suitability of traditional approaches to reconstruction of a defect that crosses the vermilion border—healing by secondary intention, primary linear repair, full-thickness wedge repair, partial-thickness wedge repair, and combined cutaneous and mucosal advancement1—depends on the depth of the lesion.

Clinical Presentation

A 66-year-old woman with a 4×6-mm, invasive, well-differentiated squamous cell carcinoma of the left lower lip was referred for Mohs micrographic surgery. Removal of the tumor required 2 stages to obtain clear margins, leaving a 1.0×1.2-cm defect that crossed the vermilion border (Figure, A). How would you repair this defect?

A, A 1×1.2-cm defect of the lower lip, involving the vermilion and cutaneous lip. The vermilion border is outlined prior to the start of extirpation of the tumor. B, Illustration of the proposed incision lines and direction of tissue movement (arrow). C, Completed repair, demonstrating proper placement of the vermilion border and lack of displacement of the lip. D, At 11-month follow-up, there is no distortion of the vermilion border. The patient reports no functional deficit.

Selecting a Technique to Close the Surgical Defect

For this patient, we had several options to consider in approaching closure, including several that we rejected. Because the defect crossed cosmetic subunit boundaries, healing by secondary intention was avoided, as it would cause contraction, obliterate the vermilion border, and result in poor functional and cosmetic results. We decided against primary closure, even with careful attention to reapproximation of the vermilion border, because the width of the defect would have required a large Burow triangle that extended into the oral cavity. For defects less than one-third the width of the lip, full-thickness wedge repair can yield excellent cosmetic results but, in this case, would decrease the oral aperture and was deemed too extensive a procedure for a relatively shallow defect.2

Instead, we chose to perform repair with V to Y advancement of skin below the cutaneous defect, up to the location of the absent vermilion border, combined with small, horizontal, linear closure of the mucosal portion of the defect. This approach is a variation of a repair described by Jin et al,3 who described using 2 opposing V-Y advancement flaps to repair defects of the lip. This repair has provided excellent cosmetic results for a small series of our patients, preserving the oral aperture and maintaining the important aesthetic location of the vermilion border. In addition, the technique makes it unnecessary for the patient to undergo a much larger repair, such as a full- or partial-thickness wedge when the initial defect is relatively shallow.

Closure Technique

It is essential to properly outline the vermilion border of the lip before initiating the repair, ideally before any infiltration of local anesthesia if the surgeon anticipates that tumor extirpation might cross the vermilion border.

Repair
Closing then proceeds as follows:

• The cutaneous portion of the defect is drawn out in standard V to Y fashion, carrying the incision through the dermis and into subcutaneous tissue. The pedicle of the flap is maintained at the base of the island, serving as the blood supply to the flap.

• The periphery of the flap and surrounding tissue is undermined to facilitate movement superiorly into the cutaneous portion of the defect.

• A single buried vertical mattress suture can be placed at the advancing border of the island, holding it in place at the anticipated location of the vermilion border. The secondary defect created by the advancing V is closed to help push the island into place and prevent downward tension on the free margin of the lip.

• The remaining defect of the vermilion lip is closed by removing Burow triangles at the horizontal edges on each side of the remaining defect (Figure, B). The triangles are removed completely within the mucosal lip, with the inferior edge of the triangle placed at the vermilion border.

• The defect is closed in a primary linear horizontal fashion, using buried vertical mattress sutures and cutaneous approximation.

The final appearance of the sutured defect yields a small lateral extension at the superior edge of the V to Y closure, giving the appearance of wings on the Y, prompting us to term the closure V-to-flying-Y (Figure, C).

Although the limited portion of the mucosal lip that is closed in this fashion might appear thinner than the remaining lip, it generally yields a cosmetically acceptable result in the properly selected patient. Our experience also has shown an improvement in this difference in the months following repair. A full mucosal advancement flap might result in a more uniform appearance of the lower lip, but it is a larger and more difficult procedure for the patient to endure. Additionally, a full mucosal advancement flap risks uniformly creating a much thinner lip.



Postoperative Course
Sutures were removed 1 week postoperatively. Proper location of the vermilion border, without distortion of the free margin, was demonstrated. At 11-month follow-up, excellent cosmetic and functional results were noted (Figure, D).

Practice Implications

This repair (1) demonstrates an elegant method of closing a relatively shallow defect that crosses the vermilion border and (2) allows the surgeon to address each cosmetic subunit individually. We have found that this repair provides excellent cosmetic and functional results, with little morbidity.

The lip is a common site of nonmelanoma squamous cell carcinoma. Poorly planned closing after excision of the tumor risks notable impairment of function or cosmetic distortion. When a defect of the lip crosses cosmetic subunits, it is helpful to repair each subunit individually. V-to-flying-Y closure is an effective method to close defects that cross the vermilion border, resulting in well-preserved cosmetic appearance and function.

Practice Gap

Reconstruction of a lip defect poses challenges to the dermatologic surgeon. The lip is a free margin, where excess tension can cause noticeable distortion in facial aesthetics. Distortion of that free margin might not only disrupt the appearance of the lip but affect function by impairing oral competency and mobility; therefore, when choosing a method of reconstruction, the surgeon must take free margin distortion into account. Misalignment of the vermilion border upon reconstruction will cause a poor aesthetic result in the absence of free margin distortion. When a surgical defect involves more than one cosmetic subunit of the lip, great care must be taken to repair each subunit individually to achieve the best cosmetic and functional results.

The suitability of traditional approaches to reconstruction of a defect that crosses the vermilion border—healing by secondary intention, primary linear repair, full-thickness wedge repair, partial-thickness wedge repair, and combined cutaneous and mucosal advancement1—depends on the depth of the lesion.

Clinical Presentation

A 66-year-old woman with a 4×6-mm, invasive, well-differentiated squamous cell carcinoma of the left lower lip was referred for Mohs micrographic surgery. Removal of the tumor required 2 stages to obtain clear margins, leaving a 1.0×1.2-cm defect that crossed the vermilion border (Figure, A). How would you repair this defect?

A, A 1×1.2-cm defect of the lower lip, involving the vermilion and cutaneous lip. The vermilion border is outlined prior to the start of extirpation of the tumor. B, Illustration of the proposed incision lines and direction of tissue movement (arrow). C, Completed repair, demonstrating proper placement of the vermilion border and lack of displacement of the lip. D, At 11-month follow-up, there is no distortion of the vermilion border. The patient reports no functional deficit.

Selecting a Technique to Close the Surgical Defect

For this patient, we had several options to consider in approaching closure, including several that we rejected. Because the defect crossed cosmetic subunit boundaries, healing by secondary intention was avoided, as it would cause contraction, obliterate the vermilion border, and result in poor functional and cosmetic results. We decided against primary closure, even with careful attention to reapproximation of the vermilion border, because the width of the defect would have required a large Burow triangle that extended into the oral cavity. For defects less than one-third the width of the lip, full-thickness wedge repair can yield excellent cosmetic results but, in this case, would decrease the oral aperture and was deemed too extensive a procedure for a relatively shallow defect.2

Instead, we chose to perform repair with V to Y advancement of skin below the cutaneous defect, up to the location of the absent vermilion border, combined with small, horizontal, linear closure of the mucosal portion of the defect. This approach is a variation of a repair described by Jin et al,3 who described using 2 opposing V-Y advancement flaps to repair defects of the lip. This repair has provided excellent cosmetic results for a small series of our patients, preserving the oral aperture and maintaining the important aesthetic location of the vermilion border. In addition, the technique makes it unnecessary for the patient to undergo a much larger repair, such as a full- or partial-thickness wedge when the initial defect is relatively shallow.

Closure Technique

It is essential to properly outline the vermilion border of the lip before initiating the repair, ideally before any infiltration of local anesthesia if the surgeon anticipates that tumor extirpation might cross the vermilion border.

Repair
Closing then proceeds as follows:

• The cutaneous portion of the defect is drawn out in standard V to Y fashion, carrying the incision through the dermis and into subcutaneous tissue. The pedicle of the flap is maintained at the base of the island, serving as the blood supply to the flap.

• The periphery of the flap and surrounding tissue is undermined to facilitate movement superiorly into the cutaneous portion of the defect.

• A single buried vertical mattress suture can be placed at the advancing border of the island, holding it in place at the anticipated location of the vermilion border. The secondary defect created by the advancing V is closed to help push the island into place and prevent downward tension on the free margin of the lip.

• The remaining defect of the vermilion lip is closed by removing Burow triangles at the horizontal edges on each side of the remaining defect (Figure, B). The triangles are removed completely within the mucosal lip, with the inferior edge of the triangle placed at the vermilion border.

• The defect is closed in a primary linear horizontal fashion, using buried vertical mattress sutures and cutaneous approximation.

The final appearance of the sutured defect yields a small lateral extension at the superior edge of the V to Y closure, giving the appearance of wings on the Y, prompting us to term the closure V-to-flying-Y (Figure, C).

Although the limited portion of the mucosal lip that is closed in this fashion might appear thinner than the remaining lip, it generally yields a cosmetically acceptable result in the properly selected patient. Our experience also has shown an improvement in this difference in the months following repair. A full mucosal advancement flap might result in a more uniform appearance of the lower lip, but it is a larger and more difficult procedure for the patient to endure. Additionally, a full mucosal advancement flap risks uniformly creating a much thinner lip.



Postoperative Course
Sutures were removed 1 week postoperatively. Proper location of the vermilion border, without distortion of the free margin, was demonstrated. At 11-month follow-up, excellent cosmetic and functional results were noted (Figure, D).

Practice Implications

This repair (1) demonstrates an elegant method of closing a relatively shallow defect that crosses the vermilion border and (2) allows the surgeon to address each cosmetic subunit individually. We have found that this repair provides excellent cosmetic and functional results, with little morbidity.

The lip is a common site of nonmelanoma squamous cell carcinoma. Poorly planned closing after excision of the tumor risks notable impairment of function or cosmetic distortion. When a defect of the lip crosses cosmetic subunits, it is helpful to repair each subunit individually. V-to-flying-Y closure is an effective method to close defects that cross the vermilion border, resulting in well-preserved cosmetic appearance and function.

References
  1. Ishii LE, Byrne PJ. Lip reconstruction. Facial Plast Surg Clin North Am. 2009;17:445-453. doi:10.1016/j.fsc.2009.05.007
  2. Sebben JE. Wedge resection of the lip: minimizing problems. J Dermatol Surg Oncol. 1985;11:60-64. doi:10.1111/j.1524-4725.1985.tb02892.x
  3. Jin X, Teng L, Zhang C, et al. Reconstruction of partial-thickness vermilion defects with a mucosal V-Y advancement flap based on the orbicularis oris muscle. J Plast Reconstr Aesthet Surg. 2011;64:472-476. doi:10.1016/j.bjps.2010.07.017
References
  1. Ishii LE, Byrne PJ. Lip reconstruction. Facial Plast Surg Clin North Am. 2009;17:445-453. doi:10.1016/j.fsc.2009.05.007
  2. Sebben JE. Wedge resection of the lip: minimizing problems. J Dermatol Surg Oncol. 1985;11:60-64. doi:10.1111/j.1524-4725.1985.tb02892.x
  3. Jin X, Teng L, Zhang C, et al. Reconstruction of partial-thickness vermilion defects with a mucosal V-Y advancement flap based on the orbicularis oris muscle. J Plast Reconstr Aesthet Surg. 2011;64:472-476. doi:10.1016/j.bjps.2010.07.017
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High-Potency Topical Steroid Treatment of Multiple Keratoacanthomas Associated With Prurigo Nodularis

Article Type
Changed
Fri, 04/16/2021 - 15:22

 

Practice Gap

Multiple keratoacanthomas (KAs) of the legs often are a challenge to treat, especially when these lesions appear within a field of prurigo nodules. Multiple KAs associated with prurigo nodularis is a rarer finding; more often, the condition is reported on the lower limbs of elderly women with actinically damaged skin.1,2 At times, it can be difficult to distinguish between KA and prurigo nodularis in these patients, who often report notable pruritus and might have associated eczematous dermatitis.2

Keratoacanthomas often are treated with aggressive modalities, such as Mohs micrographic surgery, excision, and electrodesiccation and curettage. Some patients are hesitant to undergo surgical treatment, however, preferring a less invasive approach. Trauma from these aggressive modalities also can be associated with recurrence of existing lesions or development of new KAs, possibly related to stimulation of a local inflammatory response and upregulation of helper T cells.2-4

Acitretin and other systemic retinoids often are considered first-line therapy for multiple KAs. Cyclosporine has been added as adjunctive treatment in cases associated with prurigo nodularis or eczematous dermatitis1,2; however, these treatments have a high rate of discontinuation because of adverse effects, including transaminitis, xerostomia, alopecia (acitretin), and renal toxicity (cyclosporine).2

Another treatment option for patients with coexisting KA and prurigo nodularis is intralesional corticosteroids, often administered in combination with systemic retinoids.3 Topical 5-fluorouracil (5-FU) has been used successfully for KA, but topical treatment options are limited if 5-FU fails. Topical imiquimod and cryotherapy are thought to be of little benefit, and the appearance of new KA within imiquimod and cryotherapy treatment fields has been reported.1,2 Topical corticosteroids have been used as an adjuvant therapy for multiple KAs associated with prurigo nodularis; however, a PubMed search of articles indexed for MEDLINE using the terms keratoacanthoma and steroid and keratoacanthoma and prurigo nodularis yielded no published reports of successful use of topical corticosteroids as monotherapy.2

The Technique

For patients who want to continue topical treatment of coexisting KA and prurigo nodularis after topical 5-FU fails, we have found success applying a high-potency topical corticosteroid to affected areas under occlusion nightly for 6 to 8 weeks. This treatment not only leads to resolution of KA but also simultaneously treats prurigo nodules that might be clinically difficult to distinguish from KA in some presentations. This regimen has been implemented in our practice with remarkable reduction of KA burden and relief of pruritus.

In a 68-year-old woman who was treated with this technique, multiple biopsies had shown KA (or well-differentiated squamous cell carcinoma that appeared clinically as KA) on the shin (Figure, A) arising amid many lesions consistent with prurigo nodules. Topical 5-FU had failed, but the patient did not want to be treated with a more invasive modality, such as excision or injection.

A, Multiple keratoacanthomas on the shin prior to treatment. B, Resolution of keratoacanthomas after treatment with a highpotency topical steroid under occlusion.


Instead, we treated the patient with clobetasol propionate ointment 0.05% under occlusion nightly for 6 weeks. This strategy produced resolution of both KA and prurigo nodules (Figure, B). When lesions recurred after a few months, they were successfully re-treated with topical clobetasol under occlusion in a second 6-week course.

Practical Implications

Treatment of multiple KAs associated with prurigo nodularis can present a distinct challenge. For the subset of patients who want to pursue topical treatment, options reported in the literature are limited. We have found success treating multiple KAs and associated prurigo nodules with a high-potency topical corticosteroid under occlusion, with minimal or no adverse effects. We believe that a topical corticosteroid can be implemented easily in clinical practice before a more invasive surgical or intralesional modality is considered.

References
  1. Kwiek B, Schwartz RA. Keratoacanthoma (KA): an update and review. J Am Acad Dermatol. 2016;74:1220-1233. doi:10.1016/j.jaad.2015.11.033
  2. Wu TP, Miller K, Cohen DE, et al. Keratoacanthomas arising in association with prurigo nodules in pruritic, actinically damaged skin. J Am Acad Dermatol. 2013;69:426-430. doi:10.1016/J.JAAD.2013.03.035
  3. Sanders S, Busam KJ, Halpern AC, et al. Intralesional corticosteroid treatment of multiple eruptive keratoacanthomas: case report and review of a controversial therapy. Dermatol Surg. 2002;28:954-958. doi:10.1046/j.1524-4725.2002.02069.x
  4. Lee S, Coutts I, Ryan A, et al. Keratoacanthoma formation after skin grafting: a brief report and pathophysiological hypothesis. Australas J Dermatol. 2017;58:E117-E119. doi:10.1111/ajd.12501
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Practice Gap

Multiple keratoacanthomas (KAs) of the legs often are a challenge to treat, especially when these lesions appear within a field of prurigo nodules. Multiple KAs associated with prurigo nodularis is a rarer finding; more often, the condition is reported on the lower limbs of elderly women with actinically damaged skin.1,2 At times, it can be difficult to distinguish between KA and prurigo nodularis in these patients, who often report notable pruritus and might have associated eczematous dermatitis.2

Keratoacanthomas often are treated with aggressive modalities, such as Mohs micrographic surgery, excision, and electrodesiccation and curettage. Some patients are hesitant to undergo surgical treatment, however, preferring a less invasive approach. Trauma from these aggressive modalities also can be associated with recurrence of existing lesions or development of new KAs, possibly related to stimulation of a local inflammatory response and upregulation of helper T cells.2-4

Acitretin and other systemic retinoids often are considered first-line therapy for multiple KAs. Cyclosporine has been added as adjunctive treatment in cases associated with prurigo nodularis or eczematous dermatitis1,2; however, these treatments have a high rate of discontinuation because of adverse effects, including transaminitis, xerostomia, alopecia (acitretin), and renal toxicity (cyclosporine).2

Another treatment option for patients with coexisting KA and prurigo nodularis is intralesional corticosteroids, often administered in combination with systemic retinoids.3 Topical 5-fluorouracil (5-FU) has been used successfully for KA, but topical treatment options are limited if 5-FU fails. Topical imiquimod and cryotherapy are thought to be of little benefit, and the appearance of new KA within imiquimod and cryotherapy treatment fields has been reported.1,2 Topical corticosteroids have been used as an adjuvant therapy for multiple KAs associated with prurigo nodularis; however, a PubMed search of articles indexed for MEDLINE using the terms keratoacanthoma and steroid and keratoacanthoma and prurigo nodularis yielded no published reports of successful use of topical corticosteroids as monotherapy.2

The Technique

For patients who want to continue topical treatment of coexisting KA and prurigo nodularis after topical 5-FU fails, we have found success applying a high-potency topical corticosteroid to affected areas under occlusion nightly for 6 to 8 weeks. This treatment not only leads to resolution of KA but also simultaneously treats prurigo nodules that might be clinically difficult to distinguish from KA in some presentations. This regimen has been implemented in our practice with remarkable reduction of KA burden and relief of pruritus.

In a 68-year-old woman who was treated with this technique, multiple biopsies had shown KA (or well-differentiated squamous cell carcinoma that appeared clinically as KA) on the shin (Figure, A) arising amid many lesions consistent with prurigo nodules. Topical 5-FU had failed, but the patient did not want to be treated with a more invasive modality, such as excision or injection.

A, Multiple keratoacanthomas on the shin prior to treatment. B, Resolution of keratoacanthomas after treatment with a highpotency topical steroid under occlusion.


Instead, we treated the patient with clobetasol propionate ointment 0.05% under occlusion nightly for 6 weeks. This strategy produced resolution of both KA and prurigo nodules (Figure, B). When lesions recurred after a few months, they were successfully re-treated with topical clobetasol under occlusion in a second 6-week course.

Practical Implications

Treatment of multiple KAs associated with prurigo nodularis can present a distinct challenge. For the subset of patients who want to pursue topical treatment, options reported in the literature are limited. We have found success treating multiple KAs and associated prurigo nodules with a high-potency topical corticosteroid under occlusion, with minimal or no adverse effects. We believe that a topical corticosteroid can be implemented easily in clinical practice before a more invasive surgical or intralesional modality is considered.

 

Practice Gap

Multiple keratoacanthomas (KAs) of the legs often are a challenge to treat, especially when these lesions appear within a field of prurigo nodules. Multiple KAs associated with prurigo nodularis is a rarer finding; more often, the condition is reported on the lower limbs of elderly women with actinically damaged skin.1,2 At times, it can be difficult to distinguish between KA and prurigo nodularis in these patients, who often report notable pruritus and might have associated eczematous dermatitis.2

Keratoacanthomas often are treated with aggressive modalities, such as Mohs micrographic surgery, excision, and electrodesiccation and curettage. Some patients are hesitant to undergo surgical treatment, however, preferring a less invasive approach. Trauma from these aggressive modalities also can be associated with recurrence of existing lesions or development of new KAs, possibly related to stimulation of a local inflammatory response and upregulation of helper T cells.2-4

Acitretin and other systemic retinoids often are considered first-line therapy for multiple KAs. Cyclosporine has been added as adjunctive treatment in cases associated with prurigo nodularis or eczematous dermatitis1,2; however, these treatments have a high rate of discontinuation because of adverse effects, including transaminitis, xerostomia, alopecia (acitretin), and renal toxicity (cyclosporine).2

Another treatment option for patients with coexisting KA and prurigo nodularis is intralesional corticosteroids, often administered in combination with systemic retinoids.3 Topical 5-fluorouracil (5-FU) has been used successfully for KA, but topical treatment options are limited if 5-FU fails. Topical imiquimod and cryotherapy are thought to be of little benefit, and the appearance of new KA within imiquimod and cryotherapy treatment fields has been reported.1,2 Topical corticosteroids have been used as an adjuvant therapy for multiple KAs associated with prurigo nodularis; however, a PubMed search of articles indexed for MEDLINE using the terms keratoacanthoma and steroid and keratoacanthoma and prurigo nodularis yielded no published reports of successful use of topical corticosteroids as monotherapy.2

The Technique

For patients who want to continue topical treatment of coexisting KA and prurigo nodularis after topical 5-FU fails, we have found success applying a high-potency topical corticosteroid to affected areas under occlusion nightly for 6 to 8 weeks. This treatment not only leads to resolution of KA but also simultaneously treats prurigo nodules that might be clinically difficult to distinguish from KA in some presentations. This regimen has been implemented in our practice with remarkable reduction of KA burden and relief of pruritus.

In a 68-year-old woman who was treated with this technique, multiple biopsies had shown KA (or well-differentiated squamous cell carcinoma that appeared clinically as KA) on the shin (Figure, A) arising amid many lesions consistent with prurigo nodules. Topical 5-FU had failed, but the patient did not want to be treated with a more invasive modality, such as excision or injection.

A, Multiple keratoacanthomas on the shin prior to treatment. B, Resolution of keratoacanthomas after treatment with a highpotency topical steroid under occlusion.


Instead, we treated the patient with clobetasol propionate ointment 0.05% under occlusion nightly for 6 weeks. This strategy produced resolution of both KA and prurigo nodules (Figure, B). When lesions recurred after a few months, they were successfully re-treated with topical clobetasol under occlusion in a second 6-week course.

Practical Implications

Treatment of multiple KAs associated with prurigo nodularis can present a distinct challenge. For the subset of patients who want to pursue topical treatment, options reported in the literature are limited. We have found success treating multiple KAs and associated prurigo nodules with a high-potency topical corticosteroid under occlusion, with minimal or no adverse effects. We believe that a topical corticosteroid can be implemented easily in clinical practice before a more invasive surgical or intralesional modality is considered.

References
  1. Kwiek B, Schwartz RA. Keratoacanthoma (KA): an update and review. J Am Acad Dermatol. 2016;74:1220-1233. doi:10.1016/j.jaad.2015.11.033
  2. Wu TP, Miller K, Cohen DE, et al. Keratoacanthomas arising in association with prurigo nodules in pruritic, actinically damaged skin. J Am Acad Dermatol. 2013;69:426-430. doi:10.1016/J.JAAD.2013.03.035
  3. Sanders S, Busam KJ, Halpern AC, et al. Intralesional corticosteroid treatment of multiple eruptive keratoacanthomas: case report and review of a controversial therapy. Dermatol Surg. 2002;28:954-958. doi:10.1046/j.1524-4725.2002.02069.x
  4. Lee S, Coutts I, Ryan A, et al. Keratoacanthoma formation after skin grafting: a brief report and pathophysiological hypothesis. Australas J Dermatol. 2017;58:E117-E119. doi:10.1111/ajd.12501
References
  1. Kwiek B, Schwartz RA. Keratoacanthoma (KA): an update and review. J Am Acad Dermatol. 2016;74:1220-1233. doi:10.1016/j.jaad.2015.11.033
  2. Wu TP, Miller K, Cohen DE, et al. Keratoacanthomas arising in association with prurigo nodules in pruritic, actinically damaged skin. J Am Acad Dermatol. 2013;69:426-430. doi:10.1016/J.JAAD.2013.03.035
  3. Sanders S, Busam KJ, Halpern AC, et al. Intralesional corticosteroid treatment of multiple eruptive keratoacanthomas: case report and review of a controversial therapy. Dermatol Surg. 2002;28:954-958. doi:10.1046/j.1524-4725.2002.02069.x
  4. Lee S, Coutts I, Ryan A, et al. Keratoacanthoma formation after skin grafting: a brief report and pathophysiological hypothesis. Australas J Dermatol. 2017;58:E117-E119. doi:10.1111/ajd.12501
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Hidden Basal Cell Carcinoma in the Intergluteal Crease

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Practice Gap

Basal cell carcinoma (BCC) is the most common cancer, and its incidence is on the rise.1 The risk of this skin cancer is increased when there is a history of squamous cell carcinoma (SCC) or BCC.2 Basal cell carcinoma often is found in sun-exposed areas, most commonly due to a history of intense sunburn.3 Other risk factors include male gender and increased age.4

Eighty percent to 85% of BCCs present on the head and neck5; however, BCC also can occur in unusual locations. When BCC presents in areas such as the perianal region, it is found to be larger than when found in more common areas,6 likely because neoplasms in this sensitive area often are overlooked. Literature on BCC of the intergluteal crease is limited.7 Being educated on the existence of BCC in this sensitive area can aid proper diagnosis.

The Technique and Case

An 83-year-old woman presented to the dermatology clinic for a suspicious lesion in the intergluteal crease that was tender to palpation with drainage. She first noticed this lesion and reported it to her primary care physician at a visit 6 months prior. The primary care physician did not pursue investigation of the lesion. One month later, the patient was seen by a gastroenterologist for the lesion and was referred to dermatology. The patient’s medical history included SCC and BCC on the face, both treated successfully with Mohs micrographic surgery.

Physical examination revealed a 2.6×1.1-cm, erythematous, nodular plaque in the coccygeal area of the intergluteal crease (Figure 1). A shave biopsy disclosed BCC, nodular type, ulcerated. Microscopically, there were nodular aggregates of basaloid cells with hyperchromatic nuclei and peripheral palisading, separated from mucinous stromal surroundings by artefactual clefts.

Figure 1. Basal cell carcinoma in the coccygeal region.


The initial differential diagnosis for this patient’s lesion included an ulcer or SCC. Basal cell carcinoma was not suspected due to the location and appearance of the lesion. The patient was successfully treated with Mohs micrographic surgery.

Practical Implications

Without thorough examination, this cancerous lesion would not have been seen (Figure 2). Therefore, it is important to practice thorough physical examination skills to avoid missing these cancers, particularly when examining a patient with a history of SCC or BCC. Furthermore, biopsy is recommended for suspicious lesions to rule out BCC.

Figure 2. Hidden coccygeal lesion.

Be careful not to get caught up in epidemiological or demographic considerations when making a diagnosis of this kind or when assessing the severity of a lesion. This patient, for instance, was female, which makes her less likely to present with BCC.8 Moreover, the cancer presented in a highly unlikely location for BCC, where there had not been significant sunburn.9 Patients and physicians should be educated about the incidence of BCC in unexpected areas; without a second and close look, this BCC could have been missed.

Final Thoughts

The literature continuously demonstrates the rarity of BCC in the intergluteal crease.10 However, when perianal BCC is properly identified and treated with local excision, prognosis is good.11 Basal cell carcinoma has been seen to arise in other sensitive locations; vulvar, nipple, and scrotal BCC neoplasms are among the uncommon locations where BCC has appeared.12 These areas are frequently—and easily—ignored. A total-body skin examination should be performed to ensure that these insidious-onset carcinomas are not overlooked to protect patients from the adverse consequences of untreated cancer.13

References
  1. Roewert-Huber J, Lange-Asschenfeldt B, Stockfleth E, et al. Epidemiology and aetiology of basal cell carcinoma. Br J Dermatol. 2007;157(suppl 2):47-51.
  2. Rogers HW, Weinstock MA, Feldman SR, et al. Incidence estimate of nonmelanoma skin cancer (keratinocyte carcinomas) in the US population, 2012. JAMA Dermatol. 2015;151:1081-1086.
  3. Zanetti R, Rosso S, Martinez C, et al. Comparison of risk patterns in carcinoma and melanoma of the skin in men: a multi-centre case–case–control study. Br J Cancer. 2006;94:743-751.
  4. Marzuka AG, Book SE. Basal cell carcinoma: pathogenesis, epidemiology, clinical features, diagnosis, histopathology, and management. Yale J Biol Med. 2015;88:167-179.
  5. Lorenzini M, Gatti S, Giannitrapani A. Giant basal cell carcinoma of the thoracic wall: a case report and review of the literature. Br J Plast Surg. 2005;58:1007-1010.
  6. Lee HS, Kim SK. Basal cell carcinoma presenting as a perianal ulcer and treated with radiotherapy. Ann Dermatol. 2015;27:212-214.
  7. Salih AM, Kakamad FH, Rauf GM. Basal cell carcinoma mimicking pilonidal sinus: a case report with literature review. Int J Surg Case Rep. 2016;28:121-123.
  8. Scrivener Y, Grosshans E, Cribier B. Variations of basal cell carcinomas according to gender, age, location and histopathological subtype. Br J Dermatol. 2002;147:41-47.
  9. Park J, Cho Y-S, Song K-H, et al. Basal cell carcinoma on the pubic area: report of a case and review of 19 Korean cases of BCC from non-sun-exposed areas. Ann Dermatol. 2011;23:405-408.
  10. Damin DC, Rosito MA, Gus P, et al. Perianal basal cell carcinoma. J Cutan Med Surg. 2002;6:26-28.
  11. Paterson CA, Young-Fadok TM, Dozois RR. Basal cell carcinoma of the perianal region: 20-year experience. Dis Colon Rectum. 1999;42:1200-1202.
  12. Mulvany NJ, Rayoo M, Allen DG. Basal cell carcinoma of the vulva: a case series. Pathology. 2012;44:528-533.
  13. Leonard D, Beddy D, Dozois EJ. Neoplasms of anal canal and perianal skin. Clin Colon Rectal Surg. 2011;24:54-63.
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Ms. Schwartzberg is from New York Institute of Technology College of Osteopathic Medicine, Old Westbury. Dr. Arora is from the Ronald O. Perelman Department of Dermatology, New York University Langone Health, New York, and Borealis Dermatology, Garden City, New York.

The authors report no conflict of interest.

Correspondence: Lauren Schwartzberg, OMS-IV ([email protected]). 

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Ms. Schwartzberg is from New York Institute of Technology College of Osteopathic Medicine, Old Westbury. Dr. Arora is from the Ronald O. Perelman Department of Dermatology, New York University Langone Health, New York, and Borealis Dermatology, Garden City, New York.

The authors report no conflict of interest.

Correspondence: Lauren Schwartzberg, OMS-IV ([email protected]). 

Author and Disclosure Information

Ms. Schwartzberg is from New York Institute of Technology College of Osteopathic Medicine, Old Westbury. Dr. Arora is from the Ronald O. Perelman Department of Dermatology, New York University Langone Health, New York, and Borealis Dermatology, Garden City, New York.

The authors report no conflict of interest.

Correspondence: Lauren Schwartzberg, OMS-IV ([email protected]). 

Article PDF
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Practice Gap

Basal cell carcinoma (BCC) is the most common cancer, and its incidence is on the rise.1 The risk of this skin cancer is increased when there is a history of squamous cell carcinoma (SCC) or BCC.2 Basal cell carcinoma often is found in sun-exposed areas, most commonly due to a history of intense sunburn.3 Other risk factors include male gender and increased age.4

Eighty percent to 85% of BCCs present on the head and neck5; however, BCC also can occur in unusual locations. When BCC presents in areas such as the perianal region, it is found to be larger than when found in more common areas,6 likely because neoplasms in this sensitive area often are overlooked. Literature on BCC of the intergluteal crease is limited.7 Being educated on the existence of BCC in this sensitive area can aid proper diagnosis.

The Technique and Case

An 83-year-old woman presented to the dermatology clinic for a suspicious lesion in the intergluteal crease that was tender to palpation with drainage. She first noticed this lesion and reported it to her primary care physician at a visit 6 months prior. The primary care physician did not pursue investigation of the lesion. One month later, the patient was seen by a gastroenterologist for the lesion and was referred to dermatology. The patient’s medical history included SCC and BCC on the face, both treated successfully with Mohs micrographic surgery.

Physical examination revealed a 2.6×1.1-cm, erythematous, nodular plaque in the coccygeal area of the intergluteal crease (Figure 1). A shave biopsy disclosed BCC, nodular type, ulcerated. Microscopically, there were nodular aggregates of basaloid cells with hyperchromatic nuclei and peripheral palisading, separated from mucinous stromal surroundings by artefactual clefts.

Figure 1. Basal cell carcinoma in the coccygeal region.


The initial differential diagnosis for this patient’s lesion included an ulcer or SCC. Basal cell carcinoma was not suspected due to the location and appearance of the lesion. The patient was successfully treated with Mohs micrographic surgery.

Practical Implications

Without thorough examination, this cancerous lesion would not have been seen (Figure 2). Therefore, it is important to practice thorough physical examination skills to avoid missing these cancers, particularly when examining a patient with a history of SCC or BCC. Furthermore, biopsy is recommended for suspicious lesions to rule out BCC.

Figure 2. Hidden coccygeal lesion.

Be careful not to get caught up in epidemiological or demographic considerations when making a diagnosis of this kind or when assessing the severity of a lesion. This patient, for instance, was female, which makes her less likely to present with BCC.8 Moreover, the cancer presented in a highly unlikely location for BCC, where there had not been significant sunburn.9 Patients and physicians should be educated about the incidence of BCC in unexpected areas; without a second and close look, this BCC could have been missed.

Final Thoughts

The literature continuously demonstrates the rarity of BCC in the intergluteal crease.10 However, when perianal BCC is properly identified and treated with local excision, prognosis is good.11 Basal cell carcinoma has been seen to arise in other sensitive locations; vulvar, nipple, and scrotal BCC neoplasms are among the uncommon locations where BCC has appeared.12 These areas are frequently—and easily—ignored. A total-body skin examination should be performed to ensure that these insidious-onset carcinomas are not overlooked to protect patients from the adverse consequences of untreated cancer.13

 

Practice Gap

Basal cell carcinoma (BCC) is the most common cancer, and its incidence is on the rise.1 The risk of this skin cancer is increased when there is a history of squamous cell carcinoma (SCC) or BCC.2 Basal cell carcinoma often is found in sun-exposed areas, most commonly due to a history of intense sunburn.3 Other risk factors include male gender and increased age.4

Eighty percent to 85% of BCCs present on the head and neck5; however, BCC also can occur in unusual locations. When BCC presents in areas such as the perianal region, it is found to be larger than when found in more common areas,6 likely because neoplasms in this sensitive area often are overlooked. Literature on BCC of the intergluteal crease is limited.7 Being educated on the existence of BCC in this sensitive area can aid proper diagnosis.

The Technique and Case

An 83-year-old woman presented to the dermatology clinic for a suspicious lesion in the intergluteal crease that was tender to palpation with drainage. She first noticed this lesion and reported it to her primary care physician at a visit 6 months prior. The primary care physician did not pursue investigation of the lesion. One month later, the patient was seen by a gastroenterologist for the lesion and was referred to dermatology. The patient’s medical history included SCC and BCC on the face, both treated successfully with Mohs micrographic surgery.

Physical examination revealed a 2.6×1.1-cm, erythematous, nodular plaque in the coccygeal area of the intergluteal crease (Figure 1). A shave biopsy disclosed BCC, nodular type, ulcerated. Microscopically, there were nodular aggregates of basaloid cells with hyperchromatic nuclei and peripheral palisading, separated from mucinous stromal surroundings by artefactual clefts.

Figure 1. Basal cell carcinoma in the coccygeal region.


The initial differential diagnosis for this patient’s lesion included an ulcer or SCC. Basal cell carcinoma was not suspected due to the location and appearance of the lesion. The patient was successfully treated with Mohs micrographic surgery.

Practical Implications

Without thorough examination, this cancerous lesion would not have been seen (Figure 2). Therefore, it is important to practice thorough physical examination skills to avoid missing these cancers, particularly when examining a patient with a history of SCC or BCC. Furthermore, biopsy is recommended for suspicious lesions to rule out BCC.

Figure 2. Hidden coccygeal lesion.

Be careful not to get caught up in epidemiological or demographic considerations when making a diagnosis of this kind or when assessing the severity of a lesion. This patient, for instance, was female, which makes her less likely to present with BCC.8 Moreover, the cancer presented in a highly unlikely location for BCC, where there had not been significant sunburn.9 Patients and physicians should be educated about the incidence of BCC in unexpected areas; without a second and close look, this BCC could have been missed.

Final Thoughts

The literature continuously demonstrates the rarity of BCC in the intergluteal crease.10 However, when perianal BCC is properly identified and treated with local excision, prognosis is good.11 Basal cell carcinoma has been seen to arise in other sensitive locations; vulvar, nipple, and scrotal BCC neoplasms are among the uncommon locations where BCC has appeared.12 These areas are frequently—and easily—ignored. A total-body skin examination should be performed to ensure that these insidious-onset carcinomas are not overlooked to protect patients from the adverse consequences of untreated cancer.13

References
  1. Roewert-Huber J, Lange-Asschenfeldt B, Stockfleth E, et al. Epidemiology and aetiology of basal cell carcinoma. Br J Dermatol. 2007;157(suppl 2):47-51.
  2. Rogers HW, Weinstock MA, Feldman SR, et al. Incidence estimate of nonmelanoma skin cancer (keratinocyte carcinomas) in the US population, 2012. JAMA Dermatol. 2015;151:1081-1086.
  3. Zanetti R, Rosso S, Martinez C, et al. Comparison of risk patterns in carcinoma and melanoma of the skin in men: a multi-centre case–case–control study. Br J Cancer. 2006;94:743-751.
  4. Marzuka AG, Book SE. Basal cell carcinoma: pathogenesis, epidemiology, clinical features, diagnosis, histopathology, and management. Yale J Biol Med. 2015;88:167-179.
  5. Lorenzini M, Gatti S, Giannitrapani A. Giant basal cell carcinoma of the thoracic wall: a case report and review of the literature. Br J Plast Surg. 2005;58:1007-1010.
  6. Lee HS, Kim SK. Basal cell carcinoma presenting as a perianal ulcer and treated with radiotherapy. Ann Dermatol. 2015;27:212-214.
  7. Salih AM, Kakamad FH, Rauf GM. Basal cell carcinoma mimicking pilonidal sinus: a case report with literature review. Int J Surg Case Rep. 2016;28:121-123.
  8. Scrivener Y, Grosshans E, Cribier B. Variations of basal cell carcinomas according to gender, age, location and histopathological subtype. Br J Dermatol. 2002;147:41-47.
  9. Park J, Cho Y-S, Song K-H, et al. Basal cell carcinoma on the pubic area: report of a case and review of 19 Korean cases of BCC from non-sun-exposed areas. Ann Dermatol. 2011;23:405-408.
  10. Damin DC, Rosito MA, Gus P, et al. Perianal basal cell carcinoma. J Cutan Med Surg. 2002;6:26-28.
  11. Paterson CA, Young-Fadok TM, Dozois RR. Basal cell carcinoma of the perianal region: 20-year experience. Dis Colon Rectum. 1999;42:1200-1202.
  12. Mulvany NJ, Rayoo M, Allen DG. Basal cell carcinoma of the vulva: a case series. Pathology. 2012;44:528-533.
  13. Leonard D, Beddy D, Dozois EJ. Neoplasms of anal canal and perianal skin. Clin Colon Rectal Surg. 2011;24:54-63.
References
  1. Roewert-Huber J, Lange-Asschenfeldt B, Stockfleth E, et al. Epidemiology and aetiology of basal cell carcinoma. Br J Dermatol. 2007;157(suppl 2):47-51.
  2. Rogers HW, Weinstock MA, Feldman SR, et al. Incidence estimate of nonmelanoma skin cancer (keratinocyte carcinomas) in the US population, 2012. JAMA Dermatol. 2015;151:1081-1086.
  3. Zanetti R, Rosso S, Martinez C, et al. Comparison of risk patterns in carcinoma and melanoma of the skin in men: a multi-centre case–case–control study. Br J Cancer. 2006;94:743-751.
  4. Marzuka AG, Book SE. Basal cell carcinoma: pathogenesis, epidemiology, clinical features, diagnosis, histopathology, and management. Yale J Biol Med. 2015;88:167-179.
  5. Lorenzini M, Gatti S, Giannitrapani A. Giant basal cell carcinoma of the thoracic wall: a case report and review of the literature. Br J Plast Surg. 2005;58:1007-1010.
  6. Lee HS, Kim SK. Basal cell carcinoma presenting as a perianal ulcer and treated with radiotherapy. Ann Dermatol. 2015;27:212-214.
  7. Salih AM, Kakamad FH, Rauf GM. Basal cell carcinoma mimicking pilonidal sinus: a case report with literature review. Int J Surg Case Rep. 2016;28:121-123.
  8. Scrivener Y, Grosshans E, Cribier B. Variations of basal cell carcinomas according to gender, age, location and histopathological subtype. Br J Dermatol. 2002;147:41-47.
  9. Park J, Cho Y-S, Song K-H, et al. Basal cell carcinoma on the pubic area: report of a case and review of 19 Korean cases of BCC from non-sun-exposed areas. Ann Dermatol. 2011;23:405-408.
  10. Damin DC, Rosito MA, Gus P, et al. Perianal basal cell carcinoma. J Cutan Med Surg. 2002;6:26-28.
  11. Paterson CA, Young-Fadok TM, Dozois RR. Basal cell carcinoma of the perianal region: 20-year experience. Dis Colon Rectum. 1999;42:1200-1202.
  12. Mulvany NJ, Rayoo M, Allen DG. Basal cell carcinoma of the vulva: a case series. Pathology. 2012;44:528-533.
  13. Leonard D, Beddy D, Dozois EJ. Neoplasms of anal canal and perianal skin. Clin Colon Rectal Surg. 2011;24:54-63.
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Optimizing Patient Positioning During Dermatologic Surgery

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Changed
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Practice Gap

Practical patient positioning is a commonly overlooked method of tension control during excision and repair that allows for easier closure.1 Although positioning is a basic step in dermatologic surgery, it often is difficult and awkward for both the patient and physician. Here, we describe basic principles in patient positioning that increase tension across the surgical site during excision and reduce tension during closure. By reducing the amount of work required for excision and closure, procedures are completed more quickly, which increases efficiency. These techniques should be considered during dermatologic surgery at sites that are subject to both high tension and repetitive motion, such as the upper back and lower extremities.

Technique: Upper Back Procedures

When removing lesions on the upper back, lying completely prone is uncomfortable for the patient and leaves the shoulders hyperextended.2 Instead, position the patient with the arms extended anteriorly, hugging a pillow, while lying prone or on one side (Figure 1). In this position, excision of the lesion is facilitated by increased tension across the upper back. In addition, this position is notably more comfortable for the patient. During closure, the patient should lie on the side contralateral to the surgical site, with the elbow resting at the hip and the ipsilateral arm lying parallel to the torso (Figure 2).

Figure 1. Positioning the patient for excision of lesions on the upper back.

Figure 2. Positioning the patient for closure of lesions on the upper back.

Following procedures on the upper back and shoulders, we typically recommend that the patient wear an arm sling on the ipsilateral side for 1 week. Doing so reliably limits mobility postoperatively and does not require the patient to constantly monitor their movement.

Technique: Lower Extremity Procedures

Anterior Lower Extremity
During excision of a lesion on the anterior lower extremity, we recommend that the patient be positioned with their knee bent and heel resting on the examination table. Ideally, the knee is flexed at approximately a 45° angle (Figure 3).3 In this position, excision of the lesion is facilitated by increased tension across the anterior lower extremity. During closure of these lesions, the patient should lie supine with the knee fully extended and the leg resting on the surgical bed or a pillow.

Figure 3. Positioning the patient for excision of lesions on the anterior lower extremity.

Posterior Lower Extremity
During excision of lesions on the posterior lower extremity, the patient should be positioned lying prone, with the knee fully extended, resting on the surgical bed or a pillow, which facilitates excision of the lesion by increasing tension across the site. During closure of these lesions, the patient should lie on the side contralateral to the surgical site, with the leg fully extended for support. The surgical leg should be flexed at the knee at approximately a 45° angle (Figure 4).

Figure 4. Positioning the patient for closure of lesions on the posterior lower extremity.

Practice Implications

Despite being an important step, patient positioning is an often-overlooked component of dermatologic surgery. Positioning becomes even more important in areas of high tension and repetitive motion, such as the upper back and lower extremities, where the risk of wound dehiscence and poor scar cosmesis is increased.1 Experienced dermatologic surgeons should utilize patient positioning, taking advantage of tension instead of working against it.

We have found that these 2 simple principles can aid in simplifying the excision and repair processes. Increasing tension across the surgical site during excision reduces the work required by the surgeon to reach the appropriate depth. Conversely, decreased tension across the surgical site decreases the work required for closure. These principles should be considered prior to the procedure; the patient should then be positioned in a way that maximizes tension across the surgical site during excision and minimizes tension across the surgical site during closure.

Incorporating these techniques, especially at sites that are subject to both high tension and repetitive motion, such as the upper back and lower extremities, not only increases efficiency but may also reduce the risk for wound dehiscence once the patient returns home and maintains their normal level of physical activity.

References
  1. Rohrer TE, Cook JL, Kaufman AJ. Flaps and Grafts in Dermatologic Surgery. 2nd ed. Elsevier; 2007.
  2. Kantor J. Atlas of Suturing Techniques: Approaches to Surgical Wound, Laceration, and Cosmetic Repair. 2nd ed. McGraw-Hill Education; 2016.
  3. Kiwanuka E, Cruz AP. Multistep approach for improved aesthetic and functional outcomes for lower extremity wound closure after Mohs micrographic surgery. Dermatol Surg. 2017;43:704-707.
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Dr. Powell is from the Department of Dermatology, Tulane University, New Orleans, Louisiana. Drs. Guidry and Orengo are from the Department of Dermatology, Baylor College of Medicine, Houston, Texas.

The authors report no conflict of interest.

Correspondence: Emily Powell, MD ([email protected]).

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The authors report no conflict of interest.

Correspondence: Emily Powell, MD ([email protected]).

Author and Disclosure Information

Dr. Powell is from the Department of Dermatology, Tulane University, New Orleans, Louisiana. Drs. Guidry and Orengo are from the Department of Dermatology, Baylor College of Medicine, Houston, Texas.

The authors report no conflict of interest.

Correspondence: Emily Powell, MD ([email protected]).

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Related Articles

 

Practice Gap

Practical patient positioning is a commonly overlooked method of tension control during excision and repair that allows for easier closure.1 Although positioning is a basic step in dermatologic surgery, it often is difficult and awkward for both the patient and physician. Here, we describe basic principles in patient positioning that increase tension across the surgical site during excision and reduce tension during closure. By reducing the amount of work required for excision and closure, procedures are completed more quickly, which increases efficiency. These techniques should be considered during dermatologic surgery at sites that are subject to both high tension and repetitive motion, such as the upper back and lower extremities.

Technique: Upper Back Procedures

When removing lesions on the upper back, lying completely prone is uncomfortable for the patient and leaves the shoulders hyperextended.2 Instead, position the patient with the arms extended anteriorly, hugging a pillow, while lying prone or on one side (Figure 1). In this position, excision of the lesion is facilitated by increased tension across the upper back. In addition, this position is notably more comfortable for the patient. During closure, the patient should lie on the side contralateral to the surgical site, with the elbow resting at the hip and the ipsilateral arm lying parallel to the torso (Figure 2).

Figure 1. Positioning the patient for excision of lesions on the upper back.

Figure 2. Positioning the patient for closure of lesions on the upper back.

Following procedures on the upper back and shoulders, we typically recommend that the patient wear an arm sling on the ipsilateral side for 1 week. Doing so reliably limits mobility postoperatively and does not require the patient to constantly monitor their movement.

Technique: Lower Extremity Procedures

Anterior Lower Extremity
During excision of a lesion on the anterior lower extremity, we recommend that the patient be positioned with their knee bent and heel resting on the examination table. Ideally, the knee is flexed at approximately a 45° angle (Figure 3).3 In this position, excision of the lesion is facilitated by increased tension across the anterior lower extremity. During closure of these lesions, the patient should lie supine with the knee fully extended and the leg resting on the surgical bed or a pillow.

Figure 3. Positioning the patient for excision of lesions on the anterior lower extremity.

Posterior Lower Extremity
During excision of lesions on the posterior lower extremity, the patient should be positioned lying prone, with the knee fully extended, resting on the surgical bed or a pillow, which facilitates excision of the lesion by increasing tension across the site. During closure of these lesions, the patient should lie on the side contralateral to the surgical site, with the leg fully extended for support. The surgical leg should be flexed at the knee at approximately a 45° angle (Figure 4).

Figure 4. Positioning the patient for closure of lesions on the posterior lower extremity.

Practice Implications

Despite being an important step, patient positioning is an often-overlooked component of dermatologic surgery. Positioning becomes even more important in areas of high tension and repetitive motion, such as the upper back and lower extremities, where the risk of wound dehiscence and poor scar cosmesis is increased.1 Experienced dermatologic surgeons should utilize patient positioning, taking advantage of tension instead of working against it.

We have found that these 2 simple principles can aid in simplifying the excision and repair processes. Increasing tension across the surgical site during excision reduces the work required by the surgeon to reach the appropriate depth. Conversely, decreased tension across the surgical site decreases the work required for closure. These principles should be considered prior to the procedure; the patient should then be positioned in a way that maximizes tension across the surgical site during excision and minimizes tension across the surgical site during closure.

Incorporating these techniques, especially at sites that are subject to both high tension and repetitive motion, such as the upper back and lower extremities, not only increases efficiency but may also reduce the risk for wound dehiscence once the patient returns home and maintains their normal level of physical activity.

 

Practice Gap

Practical patient positioning is a commonly overlooked method of tension control during excision and repair that allows for easier closure.1 Although positioning is a basic step in dermatologic surgery, it often is difficult and awkward for both the patient and physician. Here, we describe basic principles in patient positioning that increase tension across the surgical site during excision and reduce tension during closure. By reducing the amount of work required for excision and closure, procedures are completed more quickly, which increases efficiency. These techniques should be considered during dermatologic surgery at sites that are subject to both high tension and repetitive motion, such as the upper back and lower extremities.

Technique: Upper Back Procedures

When removing lesions on the upper back, lying completely prone is uncomfortable for the patient and leaves the shoulders hyperextended.2 Instead, position the patient with the arms extended anteriorly, hugging a pillow, while lying prone or on one side (Figure 1). In this position, excision of the lesion is facilitated by increased tension across the upper back. In addition, this position is notably more comfortable for the patient. During closure, the patient should lie on the side contralateral to the surgical site, with the elbow resting at the hip and the ipsilateral arm lying parallel to the torso (Figure 2).

Figure 1. Positioning the patient for excision of lesions on the upper back.

Figure 2. Positioning the patient for closure of lesions on the upper back.

Following procedures on the upper back and shoulders, we typically recommend that the patient wear an arm sling on the ipsilateral side for 1 week. Doing so reliably limits mobility postoperatively and does not require the patient to constantly monitor their movement.

Technique: Lower Extremity Procedures

Anterior Lower Extremity
During excision of a lesion on the anterior lower extremity, we recommend that the patient be positioned with their knee bent and heel resting on the examination table. Ideally, the knee is flexed at approximately a 45° angle (Figure 3).3 In this position, excision of the lesion is facilitated by increased tension across the anterior lower extremity. During closure of these lesions, the patient should lie supine with the knee fully extended and the leg resting on the surgical bed or a pillow.

Figure 3. Positioning the patient for excision of lesions on the anterior lower extremity.

Posterior Lower Extremity
During excision of lesions on the posterior lower extremity, the patient should be positioned lying prone, with the knee fully extended, resting on the surgical bed or a pillow, which facilitates excision of the lesion by increasing tension across the site. During closure of these lesions, the patient should lie on the side contralateral to the surgical site, with the leg fully extended for support. The surgical leg should be flexed at the knee at approximately a 45° angle (Figure 4).

Figure 4. Positioning the patient for closure of lesions on the posterior lower extremity.

Practice Implications

Despite being an important step, patient positioning is an often-overlooked component of dermatologic surgery. Positioning becomes even more important in areas of high tension and repetitive motion, such as the upper back and lower extremities, where the risk of wound dehiscence and poor scar cosmesis is increased.1 Experienced dermatologic surgeons should utilize patient positioning, taking advantage of tension instead of working against it.

We have found that these 2 simple principles can aid in simplifying the excision and repair processes. Increasing tension across the surgical site during excision reduces the work required by the surgeon to reach the appropriate depth. Conversely, decreased tension across the surgical site decreases the work required for closure. These principles should be considered prior to the procedure; the patient should then be positioned in a way that maximizes tension across the surgical site during excision and minimizes tension across the surgical site during closure.

Incorporating these techniques, especially at sites that are subject to both high tension and repetitive motion, such as the upper back and lower extremities, not only increases efficiency but may also reduce the risk for wound dehiscence once the patient returns home and maintains their normal level of physical activity.

References
  1. Rohrer TE, Cook JL, Kaufman AJ. Flaps and Grafts in Dermatologic Surgery. 2nd ed. Elsevier; 2007.
  2. Kantor J. Atlas of Suturing Techniques: Approaches to Surgical Wound, Laceration, and Cosmetic Repair. 2nd ed. McGraw-Hill Education; 2016.
  3. Kiwanuka E, Cruz AP. Multistep approach for improved aesthetic and functional outcomes for lower extremity wound closure after Mohs micrographic surgery. Dermatol Surg. 2017;43:704-707.
References
  1. Rohrer TE, Cook JL, Kaufman AJ. Flaps and Grafts in Dermatologic Surgery. 2nd ed. Elsevier; 2007.
  2. Kantor J. Atlas of Suturing Techniques: Approaches to Surgical Wound, Laceration, and Cosmetic Repair. 2nd ed. McGraw-Hill Education; 2016.
  3. Kiwanuka E, Cruz AP. Multistep approach for improved aesthetic and functional outcomes for lower extremity wound closure after Mohs micrographic surgery. Dermatol Surg. 2017;43:704-707.
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Intraoperative Tissue Expansion to Allow Primary Linear Closure of 2 Large Adjacent Surgical Defects

Article Type
Changed
Tue, 11/10/2020 - 13:42

 

Practice Gap

Nonmelanoma skin cancers most commonly are found on the head and neck. In these locations, many of these malignancies will meet criteria to undergo treatment with Mohs micrographic surgery. It is becoming increasingly common for patients to have multiple lesions treated at the same time, and sometimes these lesions can be in close proximity to one another. The final size of the adjacent defects, along with the amount of normal tissue remaining between them, will determine how to best repair both defects.1 Many times, repair options are limited to the use of a larger and more extensive repair such as a flap or graft. We present a novel option to increase the options for surgical repair.

The Technique

We present a case of 2 large adjacent postsurgical defects where intraoperative tissue relaxation allowed for successful primary linear closure of both defects under notably decreased tension from baseline. A 70-year-old man presented for treatment of 2 adjacent invasive squamous cell carcinomas on the left temple and left frontal scalp. The initial lesion sizes were 2.0×1.0 and 2.0×2.0 cm, respectively. Mohs micrographic surgery was performed on both lesions, and the final defect sizes measured 2.0×1.4 and 3.0×1.6 cm, respectively. The island of normal tissue between the defects measured 2.3-cm wide. Different repair options were discussed with the patient, including allowing 1 or both lesions to heal via secondary intention, creating 1 large wound to repair with a full-thickness skin graft, using a large skin flap to cover both wounds, or utilizing a 2-to-Z flap.2 We also discussed using an intraoperative skin relaxation device to stretch the skin around 1 or both defects and close both defects in a linear fashion; the patient opted for the latter treatment option.

The left temple had adequate mobility to perform a primary closure oriented horizontally along the long axis of the defect. Although it would have been a simple repair for this lesion, the superior defect on the frontal scalp would have been subjected to increased downward tension. The scalp defect was already under considerable tension with limited tissue mobility, so closing the temple defect horizontally would have required repair of the scalp defect using a skin graft or leaving it open to heal on its own. Similarly, the force necessary to close the frontal scalp wound first would have prevented primary closure of the temple defect.

A SUTUREGARD ISR device (Sutureguard Medical Inc) was secured centrally over both defects at a 90° angle to one another to provide intraoperative tissue relaxation without undermining. The devices were held in place by a US Pharmacopeia 2-0 nylon suture and allowed to sit for 60 minutes (Figure 1).3

Figure 1. Adjacent postsurgical defects after removal of 2 separate squamous cell carcinomas. The SUTUREGARD ISR devices are oriented perpendicularly to one another prior to tightening.


After 60 minutes, the temple defect had adequate relaxion to allow a standard layered intermediate closure in a vertical orientation along the hairline using 3-0 polyglactin 910 and 3-0 nylon. Although the scalp defect was not completely approximated, it was more than 60% smaller and able to be closed at both wound edges using the same layered approach. There was a central defect area approximately 4-mm wide that was left to heal by secondary intention (Figure 2). Undermining was not used to close either defect.

Figure 2. Primary linear closure of both defects was possible after 60 minutes of intraoperative tissue expansion, with the exception of a small central area within the superior defect that was left to heal by secondary intention.


The patient tolerated the procedure well with minimal pain or discomfort. He followed standard postoperative care instructions and returned for suture removal after 14 days of healing. At the time of suture removal there were no complications. At 1-month follow-up the patient presented with excellent cosmetic results (Figure 3).

Figure 3. Excellent healing of both surgical defects 1 month after surgery.

 

 

Practice Implications

The methods of repairing 2 adjacent postsurgical defects are numerous and vary depending on the size of the individual defects, the location of the defects, and the amount of normal skin remaining between them. Various methods of closure for the adjacent defects include healing by secondary intention, primary linear closure, skin grafts, skin flaps, creating 1 larger wound to be repaired, or a combination of these approaches.1,2,4,5

In our patient, closing the high-tension wound of the scalp would have prevented both wounds from being closed in a linear fashion without first stretching the tissue. Although Zitelli5 has cited that many wounds will heal well on their own despite a large size, many patients prefer the cosmetic appearance and shorter healing time of wounds that have been closed with sutures, particularly if those defects are greater than 8-mm wide. In contrast, patients preferred the cosmetic appearance of 4-mm wounds that healed via secondary intention.6 In our case, we closed the majority of the wound and left a small 4-mm-wide portion to heal on its own. The overall outcome was excellent and healed much quicker than leaving the entire scalp defect to heal by secondary intention.

The other methods of closure, such as a 2-to-Z flap, would have been difficult given the orientation of the lesions and the island between them.2 To create this flap, an extensive amount of undermining would have been necessary, leading to serious disruption of the blood and nerve supply and an increased risk for flap necrosis. Creating 1 large wound and repairing with a flap would have similar requirements and complications.

Intraoperative tissue relaxation can be used to allow primary closure of adjacent wounds without the need for undermining. Prior research has shown that 30 minutes of stress relaxation with 20 Newtons of applied tension yields a 65% reduction in wound-closure tension.7 Orienting the devices between 45° to 90° angles to one another creates opposing tension vectors so that the closure of one defect does not prevent the closure of the other defect. Even in cases in which the defects cannot be completely approximated, closing the wound edges to create a smaller central defect can decrease healing time and lead to an excellent cosmetic outcome without the need for a flap or graft.



The SUTUREGARD ISR suture retention bridge also is cost-effective for the surgeon and the patient. The device and suture-guide washer are included in a set that retails for $35 each or $300 for a box of 12.8 The suture most commonly used to secure the device in our practice is 2-0 nylon and retails for approximately $34 for a box of 12,9 which brings the total cost with the device to around $38 per use. The updated Current Procedural Terminology guidelines from the Centers for Medicare & Medicaid Services define that an intermediate repair requires a layered closure and may include, but does not require, limited undermining. A complex linear closure must meet criteria for an intermediate closure plus at least 1 additional criterion, such as exposure of cartilage, bone, or tendons within the defect; extensive undermining; wound-edge debridement; involvement of free margins; or use of a retention suture.10 Use of a suture retention bridge such as the SUTUREGARD ISR device and therefore a retention suture qualifies the repair as a complex linear closure. Overall, use of the device expands the surgeon’s choices for surgical closures and helps to limit the need for larger, more invasive repair procedures.

References
  1. McGinness JL, Parlette HL. A novel technique using a rotation flap for repairing adjacent surgical defects. Dermatol Surg. 2006;32:272-275.
  2. Blattner CM, Perry B, Young J, et al. 2-to-Z flap for reconstruction of adjacent skin defects. J Am Acad Dermatol. 2019;80:E77-E78.
  3. Blattner CM, Perry B, Young J, et al. The use of a suture retention device to enhance tissue expansion and healing in the repair of scalp and lower leg wounds. JAAD Case Rep. 2018;4:655-661.
  4. Zivony D, Siegle RJ. Burrow’s wedge advancement flaps for reconstruction of adjacent surgical defects. Dermatol Surg. 2002;28:1162-1164.
  5. Zitelli JA. Secondary intention healing: an alternative to surgical repair. Clin Dermatol. 1984;2:92-106.
  6. Christenson LJ, Phillips PK, Weaver AL, et al. Primary closure vs second-intention treatment of skin punch biopsy sites: a randomized trial. Arch Dermatol. 2005;141:1093-1099.
  7. Lear W, Blattner CM, Mustoe TA, et al. In vivo stress relaxation of human scalp. J Mech Behav Biomed Mater. 2019;97:85-89.
  8. SUTUREGARD purchasing facts. SUTUREGARD® Medical Inc website. https://suturegard.com/SUTUREGARD-Purchasing-Facts. Accessed October 15, 2020.
  9. Shop products: suture with needle McKesson nonabsorbable uncoated black suture monofilament nylon size 2-0 18 inch suture 1-needle 26 mm length 3/8 circle reverse cutting needle. McKesson website. https://mms.mckesson.com/catalog?query=1034509. Accessed October 15, 2020.
  10. Norris S. 2020 CPT updates to wound repair guidelines. Zotec Partners website. http://zotecpartners.com/resources/2020-cpt-updates-to-wound-repair-guidelines/. Published June 4, 2020. Accessed October 21, 2020.
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From Silver Falls Dermatology, Salem, Oregon. Dr. Lear also is from the Department of Dermatologic Surgery.

Dr. Ferrell reports no conflict of interest. Dr. Lear is a cofounder and shareholder and holds a patent for the SUTUREGARD ISR device (Sutureguard Medical Inc).

Correspondence: Kelsey Ferrell, DO, 1793 13th St SE, Salem, OR 97302 ([email protected]).

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Author and Disclosure Information

From Silver Falls Dermatology, Salem, Oregon. Dr. Lear also is from the Department of Dermatologic Surgery.

Dr. Ferrell reports no conflict of interest. Dr. Lear is a cofounder and shareholder and holds a patent for the SUTUREGARD ISR device (Sutureguard Medical Inc).

Correspondence: Kelsey Ferrell, DO, 1793 13th St SE, Salem, OR 97302 ([email protected]).

Author and Disclosure Information

From Silver Falls Dermatology, Salem, Oregon. Dr. Lear also is from the Department of Dermatologic Surgery.

Dr. Ferrell reports no conflict of interest. Dr. Lear is a cofounder and shareholder and holds a patent for the SUTUREGARD ISR device (Sutureguard Medical Inc).

Correspondence: Kelsey Ferrell, DO, 1793 13th St SE, Salem, OR 97302 ([email protected]).

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Practice Gap

Nonmelanoma skin cancers most commonly are found on the head and neck. In these locations, many of these malignancies will meet criteria to undergo treatment with Mohs micrographic surgery. It is becoming increasingly common for patients to have multiple lesions treated at the same time, and sometimes these lesions can be in close proximity to one another. The final size of the adjacent defects, along with the amount of normal tissue remaining between them, will determine how to best repair both defects.1 Many times, repair options are limited to the use of a larger and more extensive repair such as a flap or graft. We present a novel option to increase the options for surgical repair.

The Technique

We present a case of 2 large adjacent postsurgical defects where intraoperative tissue relaxation allowed for successful primary linear closure of both defects under notably decreased tension from baseline. A 70-year-old man presented for treatment of 2 adjacent invasive squamous cell carcinomas on the left temple and left frontal scalp. The initial lesion sizes were 2.0×1.0 and 2.0×2.0 cm, respectively. Mohs micrographic surgery was performed on both lesions, and the final defect sizes measured 2.0×1.4 and 3.0×1.6 cm, respectively. The island of normal tissue between the defects measured 2.3-cm wide. Different repair options were discussed with the patient, including allowing 1 or both lesions to heal via secondary intention, creating 1 large wound to repair with a full-thickness skin graft, using a large skin flap to cover both wounds, or utilizing a 2-to-Z flap.2 We also discussed using an intraoperative skin relaxation device to stretch the skin around 1 or both defects and close both defects in a linear fashion; the patient opted for the latter treatment option.

The left temple had adequate mobility to perform a primary closure oriented horizontally along the long axis of the defect. Although it would have been a simple repair for this lesion, the superior defect on the frontal scalp would have been subjected to increased downward tension. The scalp defect was already under considerable tension with limited tissue mobility, so closing the temple defect horizontally would have required repair of the scalp defect using a skin graft or leaving it open to heal on its own. Similarly, the force necessary to close the frontal scalp wound first would have prevented primary closure of the temple defect.

A SUTUREGARD ISR device (Sutureguard Medical Inc) was secured centrally over both defects at a 90° angle to one another to provide intraoperative tissue relaxation without undermining. The devices were held in place by a US Pharmacopeia 2-0 nylon suture and allowed to sit for 60 minutes (Figure 1).3

Figure 1. Adjacent postsurgical defects after removal of 2 separate squamous cell carcinomas. The SUTUREGARD ISR devices are oriented perpendicularly to one another prior to tightening.


After 60 minutes, the temple defect had adequate relaxion to allow a standard layered intermediate closure in a vertical orientation along the hairline using 3-0 polyglactin 910 and 3-0 nylon. Although the scalp defect was not completely approximated, it was more than 60% smaller and able to be closed at both wound edges using the same layered approach. There was a central defect area approximately 4-mm wide that was left to heal by secondary intention (Figure 2). Undermining was not used to close either defect.

Figure 2. Primary linear closure of both defects was possible after 60 minutes of intraoperative tissue expansion, with the exception of a small central area within the superior defect that was left to heal by secondary intention.


The patient tolerated the procedure well with minimal pain or discomfort. He followed standard postoperative care instructions and returned for suture removal after 14 days of healing. At the time of suture removal there were no complications. At 1-month follow-up the patient presented with excellent cosmetic results (Figure 3).

Figure 3. Excellent healing of both surgical defects 1 month after surgery.

 

 

Practice Implications

The methods of repairing 2 adjacent postsurgical defects are numerous and vary depending on the size of the individual defects, the location of the defects, and the amount of normal skin remaining between them. Various methods of closure for the adjacent defects include healing by secondary intention, primary linear closure, skin grafts, skin flaps, creating 1 larger wound to be repaired, or a combination of these approaches.1,2,4,5

In our patient, closing the high-tension wound of the scalp would have prevented both wounds from being closed in a linear fashion without first stretching the tissue. Although Zitelli5 has cited that many wounds will heal well on their own despite a large size, many patients prefer the cosmetic appearance and shorter healing time of wounds that have been closed with sutures, particularly if those defects are greater than 8-mm wide. In contrast, patients preferred the cosmetic appearance of 4-mm wounds that healed via secondary intention.6 In our case, we closed the majority of the wound and left a small 4-mm-wide portion to heal on its own. The overall outcome was excellent and healed much quicker than leaving the entire scalp defect to heal by secondary intention.

The other methods of closure, such as a 2-to-Z flap, would have been difficult given the orientation of the lesions and the island between them.2 To create this flap, an extensive amount of undermining would have been necessary, leading to serious disruption of the blood and nerve supply and an increased risk for flap necrosis. Creating 1 large wound and repairing with a flap would have similar requirements and complications.

Intraoperative tissue relaxation can be used to allow primary closure of adjacent wounds without the need for undermining. Prior research has shown that 30 minutes of stress relaxation with 20 Newtons of applied tension yields a 65% reduction in wound-closure tension.7 Orienting the devices between 45° to 90° angles to one another creates opposing tension vectors so that the closure of one defect does not prevent the closure of the other defect. Even in cases in which the defects cannot be completely approximated, closing the wound edges to create a smaller central defect can decrease healing time and lead to an excellent cosmetic outcome without the need for a flap or graft.



The SUTUREGARD ISR suture retention bridge also is cost-effective for the surgeon and the patient. The device and suture-guide washer are included in a set that retails for $35 each or $300 for a box of 12.8 The suture most commonly used to secure the device in our practice is 2-0 nylon and retails for approximately $34 for a box of 12,9 which brings the total cost with the device to around $38 per use. The updated Current Procedural Terminology guidelines from the Centers for Medicare & Medicaid Services define that an intermediate repair requires a layered closure and may include, but does not require, limited undermining. A complex linear closure must meet criteria for an intermediate closure plus at least 1 additional criterion, such as exposure of cartilage, bone, or tendons within the defect; extensive undermining; wound-edge debridement; involvement of free margins; or use of a retention suture.10 Use of a suture retention bridge such as the SUTUREGARD ISR device and therefore a retention suture qualifies the repair as a complex linear closure. Overall, use of the device expands the surgeon’s choices for surgical closures and helps to limit the need for larger, more invasive repair procedures.

 

Practice Gap

Nonmelanoma skin cancers most commonly are found on the head and neck. In these locations, many of these malignancies will meet criteria to undergo treatment with Mohs micrographic surgery. It is becoming increasingly common for patients to have multiple lesions treated at the same time, and sometimes these lesions can be in close proximity to one another. The final size of the adjacent defects, along with the amount of normal tissue remaining between them, will determine how to best repair both defects.1 Many times, repair options are limited to the use of a larger and more extensive repair such as a flap or graft. We present a novel option to increase the options for surgical repair.

The Technique

We present a case of 2 large adjacent postsurgical defects where intraoperative tissue relaxation allowed for successful primary linear closure of both defects under notably decreased tension from baseline. A 70-year-old man presented for treatment of 2 adjacent invasive squamous cell carcinomas on the left temple and left frontal scalp. The initial lesion sizes were 2.0×1.0 and 2.0×2.0 cm, respectively. Mohs micrographic surgery was performed on both lesions, and the final defect sizes measured 2.0×1.4 and 3.0×1.6 cm, respectively. The island of normal tissue between the defects measured 2.3-cm wide. Different repair options were discussed with the patient, including allowing 1 or both lesions to heal via secondary intention, creating 1 large wound to repair with a full-thickness skin graft, using a large skin flap to cover both wounds, or utilizing a 2-to-Z flap.2 We also discussed using an intraoperative skin relaxation device to stretch the skin around 1 or both defects and close both defects in a linear fashion; the patient opted for the latter treatment option.

The left temple had adequate mobility to perform a primary closure oriented horizontally along the long axis of the defect. Although it would have been a simple repair for this lesion, the superior defect on the frontal scalp would have been subjected to increased downward tension. The scalp defect was already under considerable tension with limited tissue mobility, so closing the temple defect horizontally would have required repair of the scalp defect using a skin graft or leaving it open to heal on its own. Similarly, the force necessary to close the frontal scalp wound first would have prevented primary closure of the temple defect.

A SUTUREGARD ISR device (Sutureguard Medical Inc) was secured centrally over both defects at a 90° angle to one another to provide intraoperative tissue relaxation without undermining. The devices were held in place by a US Pharmacopeia 2-0 nylon suture and allowed to sit for 60 minutes (Figure 1).3

Figure 1. Adjacent postsurgical defects after removal of 2 separate squamous cell carcinomas. The SUTUREGARD ISR devices are oriented perpendicularly to one another prior to tightening.


After 60 minutes, the temple defect had adequate relaxion to allow a standard layered intermediate closure in a vertical orientation along the hairline using 3-0 polyglactin 910 and 3-0 nylon. Although the scalp defect was not completely approximated, it was more than 60% smaller and able to be closed at both wound edges using the same layered approach. There was a central defect area approximately 4-mm wide that was left to heal by secondary intention (Figure 2). Undermining was not used to close either defect.

Figure 2. Primary linear closure of both defects was possible after 60 minutes of intraoperative tissue expansion, with the exception of a small central area within the superior defect that was left to heal by secondary intention.


The patient tolerated the procedure well with minimal pain or discomfort. He followed standard postoperative care instructions and returned for suture removal after 14 days of healing. At the time of suture removal there were no complications. At 1-month follow-up the patient presented with excellent cosmetic results (Figure 3).

Figure 3. Excellent healing of both surgical defects 1 month after surgery.

 

 

Practice Implications

The methods of repairing 2 adjacent postsurgical defects are numerous and vary depending on the size of the individual defects, the location of the defects, and the amount of normal skin remaining between them. Various methods of closure for the adjacent defects include healing by secondary intention, primary linear closure, skin grafts, skin flaps, creating 1 larger wound to be repaired, or a combination of these approaches.1,2,4,5

In our patient, closing the high-tension wound of the scalp would have prevented both wounds from being closed in a linear fashion without first stretching the tissue. Although Zitelli5 has cited that many wounds will heal well on their own despite a large size, many patients prefer the cosmetic appearance and shorter healing time of wounds that have been closed with sutures, particularly if those defects are greater than 8-mm wide. In contrast, patients preferred the cosmetic appearance of 4-mm wounds that healed via secondary intention.6 In our case, we closed the majority of the wound and left a small 4-mm-wide portion to heal on its own. The overall outcome was excellent and healed much quicker than leaving the entire scalp defect to heal by secondary intention.

The other methods of closure, such as a 2-to-Z flap, would have been difficult given the orientation of the lesions and the island between them.2 To create this flap, an extensive amount of undermining would have been necessary, leading to serious disruption of the blood and nerve supply and an increased risk for flap necrosis. Creating 1 large wound and repairing with a flap would have similar requirements and complications.

Intraoperative tissue relaxation can be used to allow primary closure of adjacent wounds without the need for undermining. Prior research has shown that 30 minutes of stress relaxation with 20 Newtons of applied tension yields a 65% reduction in wound-closure tension.7 Orienting the devices between 45° to 90° angles to one another creates opposing tension vectors so that the closure of one defect does not prevent the closure of the other defect. Even in cases in which the defects cannot be completely approximated, closing the wound edges to create a smaller central defect can decrease healing time and lead to an excellent cosmetic outcome without the need for a flap or graft.



The SUTUREGARD ISR suture retention bridge also is cost-effective for the surgeon and the patient. The device and suture-guide washer are included in a set that retails for $35 each or $300 for a box of 12.8 The suture most commonly used to secure the device in our practice is 2-0 nylon and retails for approximately $34 for a box of 12,9 which brings the total cost with the device to around $38 per use. The updated Current Procedural Terminology guidelines from the Centers for Medicare & Medicaid Services define that an intermediate repair requires a layered closure and may include, but does not require, limited undermining. A complex linear closure must meet criteria for an intermediate closure plus at least 1 additional criterion, such as exposure of cartilage, bone, or tendons within the defect; extensive undermining; wound-edge debridement; involvement of free margins; or use of a retention suture.10 Use of a suture retention bridge such as the SUTUREGARD ISR device and therefore a retention suture qualifies the repair as a complex linear closure. Overall, use of the device expands the surgeon’s choices for surgical closures and helps to limit the need for larger, more invasive repair procedures.

References
  1. McGinness JL, Parlette HL. A novel technique using a rotation flap for repairing adjacent surgical defects. Dermatol Surg. 2006;32:272-275.
  2. Blattner CM, Perry B, Young J, et al. 2-to-Z flap for reconstruction of adjacent skin defects. J Am Acad Dermatol. 2019;80:E77-E78.
  3. Blattner CM, Perry B, Young J, et al. The use of a suture retention device to enhance tissue expansion and healing in the repair of scalp and lower leg wounds. JAAD Case Rep. 2018;4:655-661.
  4. Zivony D, Siegle RJ. Burrow’s wedge advancement flaps for reconstruction of adjacent surgical defects. Dermatol Surg. 2002;28:1162-1164.
  5. Zitelli JA. Secondary intention healing: an alternative to surgical repair. Clin Dermatol. 1984;2:92-106.
  6. Christenson LJ, Phillips PK, Weaver AL, et al. Primary closure vs second-intention treatment of skin punch biopsy sites: a randomized trial. Arch Dermatol. 2005;141:1093-1099.
  7. Lear W, Blattner CM, Mustoe TA, et al. In vivo stress relaxation of human scalp. J Mech Behav Biomed Mater. 2019;97:85-89.
  8. SUTUREGARD purchasing facts. SUTUREGARD® Medical Inc website. https://suturegard.com/SUTUREGARD-Purchasing-Facts. Accessed October 15, 2020.
  9. Shop products: suture with needle McKesson nonabsorbable uncoated black suture monofilament nylon size 2-0 18 inch suture 1-needle 26 mm length 3/8 circle reverse cutting needle. McKesson website. https://mms.mckesson.com/catalog?query=1034509. Accessed October 15, 2020.
  10. Norris S. 2020 CPT updates to wound repair guidelines. Zotec Partners website. http://zotecpartners.com/resources/2020-cpt-updates-to-wound-repair-guidelines/. Published June 4, 2020. Accessed October 21, 2020.
References
  1. McGinness JL, Parlette HL. A novel technique using a rotation flap for repairing adjacent surgical defects. Dermatol Surg. 2006;32:272-275.
  2. Blattner CM, Perry B, Young J, et al. 2-to-Z flap for reconstruction of adjacent skin defects. J Am Acad Dermatol. 2019;80:E77-E78.
  3. Blattner CM, Perry B, Young J, et al. The use of a suture retention device to enhance tissue expansion and healing in the repair of scalp and lower leg wounds. JAAD Case Rep. 2018;4:655-661.
  4. Zivony D, Siegle RJ. Burrow’s wedge advancement flaps for reconstruction of adjacent surgical defects. Dermatol Surg. 2002;28:1162-1164.
  5. Zitelli JA. Secondary intention healing: an alternative to surgical repair. Clin Dermatol. 1984;2:92-106.
  6. Christenson LJ, Phillips PK, Weaver AL, et al. Primary closure vs second-intention treatment of skin punch biopsy sites: a randomized trial. Arch Dermatol. 2005;141:1093-1099.
  7. Lear W, Blattner CM, Mustoe TA, et al. In vivo stress relaxation of human scalp. J Mech Behav Biomed Mater. 2019;97:85-89.
  8. SUTUREGARD purchasing facts. SUTUREGARD® Medical Inc website. https://suturegard.com/SUTUREGARD-Purchasing-Facts. Accessed October 15, 2020.
  9. Shop products: suture with needle McKesson nonabsorbable uncoated black suture monofilament nylon size 2-0 18 inch suture 1-needle 26 mm length 3/8 circle reverse cutting needle. McKesson website. https://mms.mckesson.com/catalog?query=1034509. Accessed October 15, 2020.
  10. Norris S. 2020 CPT updates to wound repair guidelines. Zotec Partners website. http://zotecpartners.com/resources/2020-cpt-updates-to-wound-repair-guidelines/. Published June 4, 2020. Accessed October 21, 2020.
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Approximation of Alcohol-Based Hand Sanitizer Volume Using a Toothpaste Cap

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Practice Gap

The Centers for Disease Control and Prevention recommends handwashing with soap and water or using alcohol-based hand sanitizers to prevent transmission of coronavirus disease 2019. Five steps are delineated for effective handwashing: wetting, lathering, scrubbing, rinsing, and drying. Although alcohol-based sanitizers may be perceived as more damaging to the skin, they are less likely to cause dermatitis than handwashing with soap and water.1 Instructions are precise for handwashing, while there are no recommendations for effective use of alcohol-based hand sanitizers. A common inquiry regarding alcohol-based hand sanitizers is the volume needed for efficacy without causing skin irritation.

The Technique

Approximately 1 mL of alcohol-based hand sanitizer is recommended by some manufacturers. However, abundant evidence refutes this recommendation, including a study that tested the microbial efficacy of alcohol-based sanitizers by volume. A volume of 2 mL was necessary to achieve the 2.0 log reduction of contaminants as required by the US Food and Drug Administration for antimicrobial efficacy.2 The precise measurement of hand sanitizer using a calibrated syringe before each use is impractical. Thus, we recommend using a screw-top toothpaste cap to assist in approximating the necessary volume (Figure). The cap holds approximately 1 mL of liquid as measured using a syringe; therefore, 2 caps filled with sanitizer should be used.

Visual approximation for the appropriate volume (2 mL) of an alcoholbased hand sanitizer needed for disinfection as measured by completely filling the screw-top cap of a toothpaste tube twice.

Practice Implications

The general public may be underutilizing hand sanitizer due to fear of excessive skin irritation or supply shortages, which will reduce efficacy. Patients and physicians can use this simple visual approximation to ensure adequate use of hand sanitizer volume.

References
  1. Stutz N, Becker D, Jappe U, et al. Nurses’ perceptions of the benefits and adverse effects of hand disinfection: alcohol-based hand rubs vs. hygienic handwashing: a multicentre questionnaire study with additional patch testing by the German Contact Dermatitis Research Group. Br J Dermatol. 2009;160:565-572.
  2. Kampf G, Ruselack S, Eggerstedt S, et al. Less and less-influence of volume on hand coverage and bactericidal efficacy in hand disinfection. BMC Infect Dis. 2013;13:472.
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Mr. Gupta is from the State University of New York Downstate College of Medicine, Brooklyn. Dr. Lipner is from the Department of Dermatology, Weill Cornell Medicine, New York, New York.

The authors report no conflict of interest.

Correspondence: Shari R. Lipner, MD, PhD, 1305 York Ave, New York, NY 10021 ([email protected]).

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The authors report no conflict of interest.

Correspondence: Shari R. Lipner, MD, PhD, 1305 York Ave, New York, NY 10021 ([email protected]).

Author and Disclosure Information

Mr. Gupta is from the State University of New York Downstate College of Medicine, Brooklyn. Dr. Lipner is from the Department of Dermatology, Weill Cornell Medicine, New York, New York.

The authors report no conflict of interest.

Correspondence: Shari R. Lipner, MD, PhD, 1305 York Ave, New York, NY 10021 ([email protected]).

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Practice Gap

The Centers for Disease Control and Prevention recommends handwashing with soap and water or using alcohol-based hand sanitizers to prevent transmission of coronavirus disease 2019. Five steps are delineated for effective handwashing: wetting, lathering, scrubbing, rinsing, and drying. Although alcohol-based sanitizers may be perceived as more damaging to the skin, they are less likely to cause dermatitis than handwashing with soap and water.1 Instructions are precise for handwashing, while there are no recommendations for effective use of alcohol-based hand sanitizers. A common inquiry regarding alcohol-based hand sanitizers is the volume needed for efficacy without causing skin irritation.

The Technique

Approximately 1 mL of alcohol-based hand sanitizer is recommended by some manufacturers. However, abundant evidence refutes this recommendation, including a study that tested the microbial efficacy of alcohol-based sanitizers by volume. A volume of 2 mL was necessary to achieve the 2.0 log reduction of contaminants as required by the US Food and Drug Administration for antimicrobial efficacy.2 The precise measurement of hand sanitizer using a calibrated syringe before each use is impractical. Thus, we recommend using a screw-top toothpaste cap to assist in approximating the necessary volume (Figure). The cap holds approximately 1 mL of liquid as measured using a syringe; therefore, 2 caps filled with sanitizer should be used.

Visual approximation for the appropriate volume (2 mL) of an alcoholbased hand sanitizer needed for disinfection as measured by completely filling the screw-top cap of a toothpaste tube twice.

Practice Implications

The general public may be underutilizing hand sanitizer due to fear of excessive skin irritation or supply shortages, which will reduce efficacy. Patients and physicians can use this simple visual approximation to ensure adequate use of hand sanitizer volume.

 

Practice Gap

The Centers for Disease Control and Prevention recommends handwashing with soap and water or using alcohol-based hand sanitizers to prevent transmission of coronavirus disease 2019. Five steps are delineated for effective handwashing: wetting, lathering, scrubbing, rinsing, and drying. Although alcohol-based sanitizers may be perceived as more damaging to the skin, they are less likely to cause dermatitis than handwashing with soap and water.1 Instructions are precise for handwashing, while there are no recommendations for effective use of alcohol-based hand sanitizers. A common inquiry regarding alcohol-based hand sanitizers is the volume needed for efficacy without causing skin irritation.

The Technique

Approximately 1 mL of alcohol-based hand sanitizer is recommended by some manufacturers. However, abundant evidence refutes this recommendation, including a study that tested the microbial efficacy of alcohol-based sanitizers by volume. A volume of 2 mL was necessary to achieve the 2.0 log reduction of contaminants as required by the US Food and Drug Administration for antimicrobial efficacy.2 The precise measurement of hand sanitizer using a calibrated syringe before each use is impractical. Thus, we recommend using a screw-top toothpaste cap to assist in approximating the necessary volume (Figure). The cap holds approximately 1 mL of liquid as measured using a syringe; therefore, 2 caps filled with sanitizer should be used.

Visual approximation for the appropriate volume (2 mL) of an alcoholbased hand sanitizer needed for disinfection as measured by completely filling the screw-top cap of a toothpaste tube twice.

Practice Implications

The general public may be underutilizing hand sanitizer due to fear of excessive skin irritation or supply shortages, which will reduce efficacy. Patients and physicians can use this simple visual approximation to ensure adequate use of hand sanitizer volume.

References
  1. Stutz N, Becker D, Jappe U, et al. Nurses’ perceptions of the benefits and adverse effects of hand disinfection: alcohol-based hand rubs vs. hygienic handwashing: a multicentre questionnaire study with additional patch testing by the German Contact Dermatitis Research Group. Br J Dermatol. 2009;160:565-572.
  2. Kampf G, Ruselack S, Eggerstedt S, et al. Less and less-influence of volume on hand coverage and bactericidal efficacy in hand disinfection. BMC Infect Dis. 2013;13:472.
References
  1. Stutz N, Becker D, Jappe U, et al. Nurses’ perceptions of the benefits and adverse effects of hand disinfection: alcohol-based hand rubs vs. hygienic handwashing: a multicentre questionnaire study with additional patch testing by the German Contact Dermatitis Research Group. Br J Dermatol. 2009;160:565-572.
  2. Kampf G, Ruselack S, Eggerstedt S, et al. Less and less-influence of volume on hand coverage and bactericidal efficacy in hand disinfection. BMC Infect Dis. 2013;13:472.
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Z-plasty for Correction of Standing Cutaneous Deformity

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Practice Gap

Cutaneous head and neck reconstruction following Mohs micrographic surgery frequently presents the surgical dilemma of dog-ear formation during wound closure, often necessitating excision of additional tissue to correct the standing cone, which could pose the risk for an undesirable tension vector as well as encroachment upon additional cosmetic units or sensitive anatomic structures such as a free margin. A classic Z-plasty is a transposition flap (by definition, translocation of tissue laterally about a pivot point) that corrects a dog-ear deformity without skin excision by recruiting tissue from the axis of the standing cone and redistributing it along another.

The Technique

A classic Z-plasty is designed with 3 equal limb lengths (<1 cm each) at 60° angles, abutting the pedicle of the rotation or advancement flap. The limbs can extend away from the pedicle of the flap to minimize vascular compromise. In our patient, the theoretical standing cone was located at the lateral aspect of an O to L advancement flap (Figure 1). The 2 identical triangular flaps were elevated (Figure 2A), transposed around the pivot point (Figure 2B), and inset (Figure 3). The standing cone was corrected by redistribution of tissue without excision of additional tissue, resulting in a softer and thinner scar 2 weeks (Figure 4A) and 4 months (Figure 4B) postoperatively.

Figure 1. A Z-plasty abuts the lateral edge of an O to L advancement flap at the location of the future standing cone (star). It is designed as 3 limbs at 60o angles, extending away from the pedicle of the flap.

Figure 2. A and B, The flaps of the Z-plasty are elevated and transposed around the pivot point.

Figure 3. Flaps are inset without dog-ear formation.

Figure 4. A, A soft thin scar was observed 2 weeks postoperatively. B, Excellent cosmesis was achieved 4 months postoperatively

Practice Implications

This technique can be used to correct cones following primary wound repairs or flaps. The primary advantage of this technique for dog-ear correction is tissue sparing. Disadvantages include more complex surgical planning and longer scar length compared to excisional corrective techniques. Additionally, Z-plasty requires more time to execute compared to simpler techniques.1,2

References
  1. Frodel JL, Pawar SS, Wang TD. Z-Plasty. In: Baker SR, ed. Local Flaps in Facial Reconstruction. 3rd ed. Elsevier; 2014:317-338.
  2. Hundeshagen G, Zapata-Sirvent R, Goverman J, et al. Tissue rearrangements: the power of the Z-plasty. Clin Plast Surg. 2017;44:805-812.
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From the Department of Dermatology, University of Texas Medical Branch, Galveston.

The authors report no conflict of interest.

Correspondence: Julie A. Croley, MD, 301 University Blvd, 4.112, McCullough Building, Galveston, TX 77555-1327 ([email protected]).

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The authors report no conflict of interest.

Correspondence: Julie A. Croley, MD, 301 University Blvd, 4.112, McCullough Building, Galveston, TX 77555-1327 ([email protected]).

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From the Department of Dermatology, University of Texas Medical Branch, Galveston.

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Correspondence: Julie A. Croley, MD, 301 University Blvd, 4.112, McCullough Building, Galveston, TX 77555-1327 ([email protected]).

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Practice Gap

Cutaneous head and neck reconstruction following Mohs micrographic surgery frequently presents the surgical dilemma of dog-ear formation during wound closure, often necessitating excision of additional tissue to correct the standing cone, which could pose the risk for an undesirable tension vector as well as encroachment upon additional cosmetic units or sensitive anatomic structures such as a free margin. A classic Z-plasty is a transposition flap (by definition, translocation of tissue laterally about a pivot point) that corrects a dog-ear deformity without skin excision by recruiting tissue from the axis of the standing cone and redistributing it along another.

The Technique

A classic Z-plasty is designed with 3 equal limb lengths (<1 cm each) at 60° angles, abutting the pedicle of the rotation or advancement flap. The limbs can extend away from the pedicle of the flap to minimize vascular compromise. In our patient, the theoretical standing cone was located at the lateral aspect of an O to L advancement flap (Figure 1). The 2 identical triangular flaps were elevated (Figure 2A), transposed around the pivot point (Figure 2B), and inset (Figure 3). The standing cone was corrected by redistribution of tissue without excision of additional tissue, resulting in a softer and thinner scar 2 weeks (Figure 4A) and 4 months (Figure 4B) postoperatively.

Figure 1. A Z-plasty abuts the lateral edge of an O to L advancement flap at the location of the future standing cone (star). It is designed as 3 limbs at 60o angles, extending away from the pedicle of the flap.

Figure 2. A and B, The flaps of the Z-plasty are elevated and transposed around the pivot point.

Figure 3. Flaps are inset without dog-ear formation.

Figure 4. A, A soft thin scar was observed 2 weeks postoperatively. B, Excellent cosmesis was achieved 4 months postoperatively

Practice Implications

This technique can be used to correct cones following primary wound repairs or flaps. The primary advantage of this technique for dog-ear correction is tissue sparing. Disadvantages include more complex surgical planning and longer scar length compared to excisional corrective techniques. Additionally, Z-plasty requires more time to execute compared to simpler techniques.1,2

Practice Gap

Cutaneous head and neck reconstruction following Mohs micrographic surgery frequently presents the surgical dilemma of dog-ear formation during wound closure, often necessitating excision of additional tissue to correct the standing cone, which could pose the risk for an undesirable tension vector as well as encroachment upon additional cosmetic units or sensitive anatomic structures such as a free margin. A classic Z-plasty is a transposition flap (by definition, translocation of tissue laterally about a pivot point) that corrects a dog-ear deformity without skin excision by recruiting tissue from the axis of the standing cone and redistributing it along another.

The Technique

A classic Z-plasty is designed with 3 equal limb lengths (<1 cm each) at 60° angles, abutting the pedicle of the rotation or advancement flap. The limbs can extend away from the pedicle of the flap to minimize vascular compromise. In our patient, the theoretical standing cone was located at the lateral aspect of an O to L advancement flap (Figure 1). The 2 identical triangular flaps were elevated (Figure 2A), transposed around the pivot point (Figure 2B), and inset (Figure 3). The standing cone was corrected by redistribution of tissue without excision of additional tissue, resulting in a softer and thinner scar 2 weeks (Figure 4A) and 4 months (Figure 4B) postoperatively.

Figure 1. A Z-plasty abuts the lateral edge of an O to L advancement flap at the location of the future standing cone (star). It is designed as 3 limbs at 60o angles, extending away from the pedicle of the flap.

Figure 2. A and B, The flaps of the Z-plasty are elevated and transposed around the pivot point.

Figure 3. Flaps are inset without dog-ear formation.

Figure 4. A, A soft thin scar was observed 2 weeks postoperatively. B, Excellent cosmesis was achieved 4 months postoperatively

Practice Implications

This technique can be used to correct cones following primary wound repairs or flaps. The primary advantage of this technique for dog-ear correction is tissue sparing. Disadvantages include more complex surgical planning and longer scar length compared to excisional corrective techniques. Additionally, Z-plasty requires more time to execute compared to simpler techniques.1,2

References
  1. Frodel JL, Pawar SS, Wang TD. Z-Plasty. In: Baker SR, ed. Local Flaps in Facial Reconstruction. 3rd ed. Elsevier; 2014:317-338.
  2. Hundeshagen G, Zapata-Sirvent R, Goverman J, et al. Tissue rearrangements: the power of the Z-plasty. Clin Plast Surg. 2017;44:805-812.
References
  1. Frodel JL, Pawar SS, Wang TD. Z-Plasty. In: Baker SR, ed. Local Flaps in Facial Reconstruction. 3rd ed. Elsevier; 2014:317-338.
  2. Hundeshagen G, Zapata-Sirvent R, Goverman J, et al. Tissue rearrangements: the power of the Z-plasty. Clin Plast Surg. 2017;44:805-812.
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Tip Sheet: Teledermatology 101

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