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Emerging sickle cell agents target new pathways
CONCORD, N.C. – There are a number of new drugs in the sickle cell disease pipeline, and researchers are investigating gene therapy using patients...
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Dedicated sickle cell center offers roadmap for care
CONCORD, N.C. – The Georgia Comprehensive Sickle Cell Center includes a dedicated emergency room.
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Study examines intestinal microbiota role post liver transplant
Colonization by multidrug-resistant organisms has a large effect on infections, microbiome diversity, and transplant outcomes.
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Nivolumab may extend survival in HCC patients
WASHINGTON – About 20% of patients achieved an objective remission that included complete responses in all subgroups of patients.
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Emerging oral agent reduces ALT in NAFLD
In phase 2 dose-finding study, hepatic fraction decreased in treated patients.
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Novel metabolite may be key in NAFLD
The gut microbiome–derived metabolite may be a useful biomarker.
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Hispanics bear brunt of NAFLD disease burden
Relative risk of NAFLD is higher in Hispanics, but the risk of death from NAFLD is highest in whites.
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Why VADS is gaining ground in pediatrics
Miniaturization is leading to a new era of pediatric VADs use.
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Challenges of validating cerebral protection for TAVI
Cerebral protection during TAVI is appealing, but challenging.
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Vascular risks heightened in fibrotic NAFLD
WASHINGTON – In large international study, cirrhotic patients had more liver-related adverse outcomes.
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New biomarkers improve DILI predictability
WASHINGTON – Particular biomarkers and combinations can assess inflammation and mode of hepatocyte death.
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Can arterial switch operation impact cognitive deficits?
Cognitive effects common among adults who had transposition of the great arteries.
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Study finds bivalirudin efficacy for PCI no better than heparin
Swedish study questions bivalirudin efficacy over heparin in PCI.
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C-section raises hysterectomy complication risk later
Study offers further reasons to decrease cesarean delivery when not medically indicated.
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Malperfusion key in aortic dissection repair outcomes
Malperfusion at presentation was a strong risk factor for death.